Potenciais evocados auditivos de tronco encefálico em frentistas

Ototoxicity of organic solvents can affect the hearing system up to the cochlea level and the central structures of hearing. OBJECTIVE: To evaluate the neurophysiological integrity of the hearing system in subjects exposed to fuels using ABR. METHOD: Prospective study. We evaluated attendants from three gas stations in Santa Maria/RS. The sample had 21 subjects, who were evaluated by auditory brainstem response. RESULTS: We found an alteration in the absolute latencies of Waves I and III and in all the interpeak latencies, in the right ear. In the left ear there was a change in the absolute latencies of all Waves, and in all the interpeak intervals. A change in the interaural difference of Wave V was found in 19% of the individuals. In the group exposed for more than five years, there were subjects with a statistically significant changes: in the I-V interpeak of the right ear; in the absolute latency of Wave I and in the III-V interpeak of the left year. CONCLUSION: Exposure to fuels can cause alterations in the central hearing system.

[1]  R. Keith,et al.  Peripheral and Central Auditory Dysfunction Induced by Occupational Exposure to Organic Solvents , 2009, Journal of occupational and environmental medicine.

[2]  K. Gopal Audiological findings in individuals exposed to organic solvents: case studies. , 2008, Noise & health.

[3]  Rickie R. Davis,et al.  Susceptibility to the ototoxic properties of toluene is species specific , 2002, Hearing Research.

[4]  S. P. Lund,et al.  Rats exposed to Toluene and Noise may develop Loss of Auditory Sensitivity due to Synergistic Interaction. , 2000, Noise & health.

[5]  R. Balster Neural basis of inhalant abuse. , 1998, Drug and alcohol dependence.

[6]  P. Campo,et al.  Combined effects of a simultaneous exposure to noise and toluene on hearing function. , 1997, Neurotoxicology and teratology.

[7]  P. Campo,et al.  Toluene-induced hearing loss: a mid-frequency location of the cochlear lesions. , 1997, Neurotoxicology and teratology.

[8]  A. Poblano,et al.  Potenciales provocados auditivos en adictos a la inhalación de solventes orgánicos , 1996 .

[9]  V. Božikov,et al.  Brainstem auditory evoked potentials in individuals exposed to long-term low concentrations of toluene. , 1996, American journal of industrial medicine.

[10]  N. Yamanouchi,et al.  White matter changes caused by chronic solvent abuse. , 1995, AJNR. American journal of neuroradiology.

[11]  T. Morata,et al.  Epidemiologic considerations in the evaluation of occupational hearing loss. , 1995, Occupational medicine.

[12]  B. Canlon,et al.  Progressive hair cell loss induced by toluene exposure , 1994, Hearing Research.

[13]  G K Lemasters,et al.  Effects of occupational exposure to organic solvents and noise on hearing. , 1993, Scandinavian journal of work, environment & health.

[14]  A. Fuente Auditory damage associated with solvent exposure: evidence from a cross-sectional study , 2008 .

[15]  K. Ameno,et al.  Regional brain distribution of toluene in rats and in a human autopsy , 2006, Archives of Toxicology.

[16]  T. Ledin,et al.  Audiological disturbances caused by long-term exposure to industrial solvents. Relation to the diagnosis of toxic encephalopathy. , 1998, Scandinavian audiology.

[17]  H. Hein,et al.  Mixed solvent exposure and hearing impairment: an epidemiological study of 3284 men. The Copenhagen male study. , 1993, Occupational medicine.

[18]  C. Abbate,et al.  Neurotoxicity induced by exposure to toluene , 1993, International archives of occupational and environmental health.