Clearance of activated stellate cells for hepatic fibrosis regression: molecular basis and translational potential.

[1]  B. Gao,et al.  Interleukin‐22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice , 2012, Hepatology.

[2]  Christopher K. Glass,et al.  Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis , 2012, Proceedings of the National Academy of Sciences.

[3]  Feng Zhang,et al.  Peroxisome proliferator-activated receptor-γ cross-regulation of signaling events implicated in liver fibrogenesis. , 2012, Cellular signalling.

[4]  A. Leite-Moreira,et al.  Increased hepatic expression of TLR2 and TLR4 in the hepatic inflammation-fibrosis-carcinoma sequence , 2012, Innate immunity.

[5]  G. Packham,et al.  MicroRNAs: critical regulators of epithelial to mesenchymal (EMT) and mesenchymal to epithelial transition (MET) in cancer progression , 2012, Biology of the cell.

[6]  J. Proost,et al.  PEGylation improves pharmacokinetic profile, liver uptake and efficacy of Interferon gamma in liver fibrosis. , 2011, Journal of controlled release : official journal of the Controlled Release Society.

[7]  C. Isacke,et al.  The 'alternative' EMT switch , 2011, Breast Cancer Research.

[8]  Ching-Lung Lai,et al.  A New Model Using Routinely Available Clinical Parameters to Predict Significant Liver Fibrosis in Chronic Hepatitis B , 2011, PloS one.

[9]  M. Bronner,et al.  Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation. , 2011, Cancer research.

[10]  C. Tseng,et al.  A Chinese Herbal Decoction, Modified Yi Guan Jian, Induces Apoptosis in Hepatic Stellate Cells through an ROS-Mediated Mitochondrial/Caspase Pathway , 2010, Evidence-based complementary and alternative medicine : eCAM.

[11]  D. Brigstock,et al.  Integrin expression and function in the response of primary culture hepatic stellate cells to connective tissue growth factor (CCN2) , 2010, Journal of cellular and molecular medicine.

[12]  H. Senoo,et al.  Hepatic stellate cell (vitamin A‐storing cell) and its relative – past, present and future , 2010, Cell biology international.

[13]  C. Liu,et al.  Kupffer cells are associated with apoptosis, inflammation and fibrotic effects in hepatic fibrosis in rats , 2010, Laboratory Investigation.

[14]  L. Lau,et al.  Cellular senescence controls fibrosis in wound healing , 2010, Aging.

[15]  F. Tacke,et al.  Chemokines in Liver Inflammation and Fibrosis , 2010, Seminars in liver disease.

[16]  Yuesheng Li,et al.  Hepatic stellate cells and parasite-induced liver fibrosis , 2010, Parasites & Vectors.

[17]  R. Bataller,et al.  Reduction of advanced liver fibrosis by short‐term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats , 2010, Hepatology.

[18]  R. Domitrović,et al.  Liver fibrosis in mice induced by carbon tetrachloride and its reversion by luteolin. , 2009, Toxicology and applied pharmacology.

[19]  F. Oberti,et al.  Treatment of liver fibrosis: clinical aspects. , 2009, Gastroenterologie clinique et biologique.

[20]  W. Jeong,et al.  Diverse roles of invariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride , 2009, Hepatology.

[21]  Jun Li,et al.  Accelerative effect of leflunomide on recovery from hepatic fibrosis involves TRAIL-mediated hepatic stellate cell apoptosis. , 2009, Life sciences.

[22]  R. Liu,et al.  Inverse association between hepatic stellate cell apoptosis and fibrosis in chronic hepatitis C virus infection , 2009, Journal of viral hepatitis.

[23]  N. Kawada,et al.  Induction of tropomyosin during hepatic stellate cell activation and the progression of liver fibrosis , 2009, Hepatology international.

[24]  D. Krishnadas,et al.  In vitro activation and differentiation of naïve CD4+ and CD8+ T cells into HCV core- and NS3-specific armed effector cells: a new role for CD4+ T cells. , 2009, Cellular immunology.

[25]  D. Brenner,et al.  NK and NKT cells in liver injury and fibrosis. , 2009, Clinical immunology.

[26]  J. Fung,et al.  Hepatic Stellate Cells Preferentially Expand Allogeneic CD4+CD25+FoxP3+ Regulatory T Cells in an IL-2-Dependent Manner , 2008, Transplantation.

[27]  S. Lowe,et al.  Senescence of Activated Stellate Cells Limits Liver Fibrosis , 2008, Cell.

[28]  G. Alpini,et al.  Fate‐Mapping Evidence That Hepatic Stellate Cells Are Epithelial Progenitors in Adult Mouse Livers , 2008, Stem cells.

[29]  L. Martínez-Pérez,et al.  Partial Hepatectomy–Induced Regeneration Accelerates Reversion of Liver Fibrosis Involving Participation of Hepatic Stellate Cells , 2008, Experimental biology and medicine.

[30]  D. Peeper,et al.  Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network , 2008, Cell.

[31]  S. Friedman,et al.  Mechanisms of hepatic fibrogenesis. , 2008, Gastroenterology.

[32]  N. Barker,et al.  The upstream components of the Wnt signalling pathway in the dynamic EMT and MET associated with colorectal cancer progression , 2008, Clinical & Experimental Metastasis.

[33]  H. Tsukamoto,et al.  Fat paradox of steatohepatitis , 2008, Journal of gastroenterology and hepatology.

[34]  H. Tsukamoto,et al.  Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis. , 2008, American journal of physiology. Gastrointestinal and liver physiology.

[35]  Y. Matsuzaki,et al.  Liver Fibrosis: Possible Involvement of EMT , 2007, Cells Tissues Organs.

[36]  E. Thompson,et al.  Mesenchymal to Epithelial Transition in Development and Disease , 2007, Cells Tissues Organs.

[37]  Ashok Kumar,et al.  Hyperthyroidism induces apoptosis in rat liver through activation of death receptor-mediated pathways. , 2007, Journal of hepatology.

[38]  T. Nakajima,et al.  Role of cell‐cycle turnover and oxidative stress in telomere shortening and cellular senescence in patients with chronic hepatitis C , 2007, Journal of gastroenterology and hepatology.

[39]  Raymundo Paraná,et al.  Apoptosis y progresión de fibrosis hepática en enfermedades del hígado , 2006 .

[40]  W. Jeong,et al.  STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity , 2006, Hepatology.

[41]  M. Ziol,et al.  Interferon gamma‐secreting HCV‐specific CD8+ T cells in the liver of patients with chronic C hepatitis: relation to liver fibrosis – ANRS HC EP07 study * , 2006, Journal of viral hepatitis.

[42]  S. Friedman,et al.  Anti-fibrotic activity of NK cells in experimental liver injury through killing of activated HSC. , 2006, Journal of Hepatology.

[43]  Y. Tokusashi,et al.  Activated hepatic stellate cells overexpress p75NTR after partial hepatectomy and undergo apoptosis on nerve growth factor stimulation , 2006, Liver international : official journal of the International Association for the Study of the Liver.

[44]  R. Sun,et al.  Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D-dependent and tumor necrosis factor-related apoptosis-inducing ligand-dependent manners. , 2006, Gastroenterology.

[45]  H. Tsukamoto.  Adipogenic phenotype of hepatic stellate cells. , 2005, Alcoholism, clinical and experimental research.

[46]  B. Jawan,et al.  Interleukin-10 gene therapy reverses thioacetamide-induced liver fibrosis in mice. , 2005, Biochemical and biophysical research communications.

[47]  R. Kalluri,et al.  Bone Morphogenic Protein-7 Induces Mesenchymal to Epithelial Transition in Adult Renal Fibroblasts and Facilitates Regeneration of Injured Kidney* , 2005, Journal of Biological Chemistry.

[48]  H. Tsukamoto,et al.  Adipogenic Transcriptional Regulation of Hepatic Stellate Cells* , 2005, Journal of Biological Chemistry.

[49]  I. Endo,et al.  Role of transforming growth factor-β1 (TGF-β1) in endotoxin-induced hepatic failure after extensive hepatectomy in rats , 2005 .

[50]  S. Friedman.  Mac the knife? Macrophages- the double-edged sword of hepatic fibrosis. , 2005, The Journal of clinical investigation.

[51]  S. Forbes,et al.  Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. , 2005, The Journal of clinical investigation.

[52]  C. J. Marek,et al.  Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis. , 2005, Gastroenterology.

[53]  Anping Chen,et al.  Activation of PPARgamma is required for curcumin to induce apoptosis and to inhibit the expression of extracellular matrix genes in hepatic stellate cells in vitro. , 2004, The Biochemical journal.

[54]  J. Fallowfield,et al.  Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking. , 2004, Gastroenterology.

[55]  M. Pinzani,et al.  Liver fibrosis: from the bench to clinical targets. , 2004, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[56]  Y. Inoue,et al.  Involvement of Rho/Rho kinase pathway in regulation of apoptosis in rat hepatic stellate cells. , 2003, American journal of physiology. Gastrointestinal and liver physiology.

[57]  J. Iredale,et al.  Basement membrane-like matrix inhibits proliferation and collagen synthesis by activated rat hepatic stellate cells: evidence for matrix-dependent deactivation of stellate cells. , 2003, Matrix biology : journal of the International Society for Matrix Biology.

[58]  R. Kalluri,et al.  Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors. , 2003, Gastroenterology.

[59]  D. Häussinger,et al.  Caspase 9-dependent killing of hepatic stellate cells by activated Kupffer cells. , 2002, Gastroenterology.

[60]  J. Iredale.  Hepatic Stellate Cell Behavior during Resolution of Liver Injury , 2001, Seminars in liver disease.

[61]  M. Ueki,et al.  The fibronectin-derived antiadhesive peptides suppress the myofibroblastic conversion of rat hepatic stellate cells. , 2001, Experimental cell research.

[62]  H. Sakai,et al.  Induction of apoptosis in rat hepatic stellate cells by disruption of integrin-mediated cell adhesion. , 1999, The Journal of laboratory and clinical medicine.

[63]  S. Friedman,et al.  Maintenance of differentiated phenotype of cultured rat hepatic lipocytes by basement membrane matrix. , 1989, The Journal of biological chemistry.

[64]  L. Hayflick,et al.  The serial cultivation of human diploid cell strains. , 1961, Experimental cell research.