Effect of certain drugs on the incidence of seasickness

Several drugs were tested, some of them for the first time, against seasickness in military personnel on transport ships on the North Atlantic ocean. All of the drugs were given three fimes a day. Of the new ones tested phenglutarmide, 2.5 mg., and cinnarazine, 7.5 mg., were significantly effective on a single trip. Somewhat less effective were atropine and orphenadrine.

[1]  W. R. Trotter,et al.  PREVENTION OF SEASICKNESS BY DRUGS , 1944 .

[2]  P. K. Smith The effectiveness of some motion sickness remedies in preventing air sickness in Air Force Navigation students. , 1946, The Journal of aviation medicine.

[3]  P. K. Smith,et al.  Evaluation of some drugs in seasickness. , 1953, The Journal of pharmacology and experimental therapeutics.

[4]  P. K. Smith,et al.  Drugs preventing motion sickness at sea. , 1954, The Journal of pharmacology and experimental therapeutics.

[5]  B. Brodie,et al.  INTERACTION OF MONOAMINE OXIDASE INHIBITORS WITH PHYSIOLOGICAL AND BIOCHEMICAL MECHANISMS IN BRAIN , 1959, Annals of the New York Academy of Sciences.