Alternate-day fasting reverses the age-associated hypertrophy phenotype in rat heart by influencing the ERK and PI3K signaling pathways

[1]  Douglas P. Zipes,et al.  Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 2-Volume Set, 10th Edition , 2011 .

[2]  S. Rohrbach,et al.  Caloric restriction delays cardiac ageing in rats: role of mitochondria. , 2010, Cardiovascular research.

[3]  V. Dolinsky,et al.  Calorie Restriction Prevents Hypertension and Cardiac Hypertrophy in the Spontaneously Hypertensive Rat , 2010, Hypertension.

[4]  J. Hawley,et al.  Aerobic training reverses high-fat diet-induced pro-inflammatory signalling in rat skeletal muscle , 2010, European Journal of Applied Physiology.

[5]  M. Mattson,et al.  “Control” laboratory rodents are metabolically morbid: Why it matters , 2010, Proceedings of the National Academy of Sciences.

[6]  K. E. Jones,et al.  Nutrient Stress Activates Inflammation and Reduces Glucose Metabolism by Suppressing AMP-Activated Protein Kinase in the Heart , 2009, Diabetes.

[7]  Sterling C. Johnson,et al.  Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys , 2009, Science.

[8]  K. Okumura,et al.  Mechanism of Diastolic Stiffening of the Failing Myocardium and Its Prevention by Angiotensin Receptor and Calcium Channel Blockers , 2009, Journal of cardiovascular pharmacology.

[9]  S. Clément,et al.  Modulation of actin isoform expression before the transition from experimental compensated pressure-overload cardiac hypertrophy to decompensation. , 2009, American journal of physiology. Heart and circulatory physiology.

[10]  Richard Weindruch,et al.  Caloric Restriction and Aging: Studies in Mice and Monkeys , 2009, Toxicologic pathology.

[11]  A. D. de Bold,et al.  Cardiac Natriuretic Peptides Gene Expression and Secretion in Inflammation , 2009, Journal of Investigative Medicine.

[12]  H. Drexler,et al.  The myocardial JAK/STAT pathway: from protection to failure. , 2008, Pharmacology & therapeutics.

[13]  D. Hilfiker-Kleiner,et al.  Role of gp130‐mediated signalling pathways in the heart and its impact on potential therapeutic aspects , 2008, British journal of pharmacology.

[14]  E. Frohlich,et al.  The aging hypertensive heart: a brief update , 2008, Nature Clinical Practice Cardiovascular Medicine.

[15]  J. Holloszy,et al.  Caloric restriction in humans , 2007, Experimental Gerontology.

[16]  D. Kass,et al.  Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface , 2007, Nature Reviews Drug Discovery.

[17]  G. Dorn The Fuzzy Logic of Physiological Cardiac Hypertrophy , 2007, Hypertension.

[18]  G. Norton,et al.  Rat strain-related differences in myocardial adrenergic tone and the impact on cardiac fibrosis, adrenergic responsiveness and myocardial structure and function. , 2007, Pharmacological research.

[19]  P. Kopelman Health risks associated with overweight and obesity , 2007, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[20]  Corby K. Martin,et al.  Effect of calorie restriction with or without exercise on body composition and fat distribution. , 2007, The Journal of clinical endocrinology and metabolism.

[21]  J. Molkentin,et al.  Regulation of cardiac hypertrophy by intracellular signalling pathways , 2006, Nature Reviews Molecular Cell Biology.

[22]  R. Kennedy,et al.  Using U0126 to dissect the role of the extracellular signal-regulated kinase 1/2 (ERK1/2) cascade in the regulation of gene expression by endothelin-1 in cardiac myocytes. , 2006, Journal of molecular and cellular cardiology.

[23]  F. Ohsuzu,et al.  Left ventricular hypertrophy in mice with a cardiac-specific overexpression of interleukin-1. , 2006, American journal of physiology. Heart and circulatory physiology.

[24]  S. Clément,et al.  Correlation of α‐skeletal actin expression, ventricular fibrosis and heart function with the degree of pressure overload cardiac hypertrophy in rats , 2006 .

[25]  J. Dhahbi,et al.  Gene expression and physiologic responses of the heart to the initiation and withdrawal of caloric restriction. , 2006, The journals of gerontology. Series A, Biological sciences and medical sciences.

[26]  A. Gradman,et al.  From left ventricular hypertrophy to congestive heart failure: management of hypertensive heart disease. , 2006, Progress in cardiovascular diseases.

[27]  A. Clerk,et al.  Peptide growth factors signal differentially through protein kinase C to extracellular signal-regulated kinases in neonatal cardiomyocytes. , 2006, Cellular signalling.

[28]  A. Sapino,et al.  Calorie restriction protects against age‐related rat aorta sclerosis , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[29]  J. Lecron,et al.  Role of interleukin‐6 in cardiomyocyte/cardiac fibroblast interactions during myocyte hypertrophy and fibroblast proliferation , 2005, Journal of cellular physiology.

[30]  E. Abel,et al.  Akt1 in the cardiovascular system: friend or foe? , 2005, The Journal of clinical investigation.

[31]  Bruce Jones,et al.  The diet restriction paradigm: a brief review of the effects of every-other-day feeding , 2005, AGE.

[32]  S. Kong,et al.  Genetic expression profiles during physiological and pathological cardiac hypertrophy and heart failure in rats. , 2005, Physiological genomics.

[33]  Hyun-seung Kim,et al.  Cardiovascular disease in the elderly , 2005 .

[34]  S. Akira,et al.  Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning. , 2004, Cardiovascular research.

[35]  L. Silengo,et al.  PI3Kγ Modulates the Cardiac Response to Chronic Pressure Overload by Distinct Kinase-Dependent and -Independent Effects , 2004, Cell.

[36]  J. Johnston Are SOCS suppressors, regulators, and degraders? , 2004, Journal of leukocyte biology.

[37]  E. Olson,et al.  Hypertrophy of the heart: a new therapeutic target? , 2004, Circulation.

[38]  D. Hilton,et al.  Inhibitors of Cytokine Signal Transduction* , 2004, Journal of Biological Chemistry.

[39]  D. Berrigan,et al.  Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans. , 2003, Annual review of medicine.

[40]  S. S. Zhang,et al.  Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[41]  P. Kang,et al.  Phosphoinositide 3-kinase(p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[42]  E. Ravussin,et al.  Calorie restriction and aging: review of the literature and implications for studies in humans. , 2003, The American journal of clinical nutrition.

[43]  M. Mattson,et al.  Intermittent food deprivation improves cardiovascular and neuroendocrine responses to stress in rats. , 2003, The Journal of nutrition.

[44]  H. Hsieh,et al.  Shear Flow Attenuates Serum-induced STAT3 Activation in Endothelial Cells* , 2003, Journal of Biological Chemistry.

[45]  A. Angelini,et al.  α‐Actin isoform distribution in normal and failing human heart: a morphological, morphometric, and biochemical study , 2003, The Journal of pathology.

[46]  A. Lichtenberg,et al.  Alterations in Janus Kinase (JAK)-Signal Transducers and Activators of Transcription (STAT) Signaling in Patients With End-Stage Dilated Cardiomyopathy , 2003, Circulation.

[47]  D. Kass,et al.  Combined Ventricular Systolic and Arterial Stiffening in Patients With Heart Failure and Preserved Ejection Fraction: Implications for Systolic and Diastolic Reserve Limitations , 2003, Circulation.

[48]  Edward G Lakatta,et al.  Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part III: Cellular and Molecular Clues to Heart and Arterial Aging , 2003, Circulation.

[49]  Daniel Levy,et al.  Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease. , 2003, Circulation.

[50]  Daniel Levy,et al.  Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease. , 2003, Circulation.

[51]  D. Aronson Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes , 2003, Journal of hypertension.

[52]  G. Booz,et al.  Interplay between the cardiac renin angiotensin system and JAK-STAT signaling: role in cardiac hypertrophy, ischemia/reperfusion dysfunction, and heart failure. , 2002, Journal of molecular and cellular cardiology.

[53]  Taber MacCallum,et al.  Calorie restriction in biosphere 2: alterations in physiologic, hematologic, hormonal, and biochemical parameters in humans restricted for a 2-year period. , 2002, The journals of gerontology. Series A, Biological sciences and medical sciences.

[54]  M. Matsuda,et al.  Physiological and pathological cardiac hypertrophy induce different molecular phenotypes in the rat. , 2001, American journal of physiology. Regulatory, integrative and comparative physiology.

[55]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[56]  J. Ross,et al.  Suppressor of cytokine signaling-3 is a biomechanical stress-inducible gene that suppresses gp130-mediated cardiac myocyte hypertrophy and survival pathways. , 2001, The Journal of clinical investigation.

[57]  N. Maulik,et al.  Role of STAT3 in ischemic preconditioning. , 2001, Journal of molecular and cellular cardiology.

[58]  J. Stern,et al.  Calorie restriction in obesity: prevention of kidney disease in rodents. , 2001, Journal of NutriLife.

[59]  T. Aoyagi,et al.  Hemodynamic Overload–Induced Activation of Myocardial Mitogen-Activated Protein Kinases In Vivo: Augmented Responses in Young Spontaneously Hypertensive Rats and Diminished Responses in Aged Fischer 344 Rats , 2001, Hypertension.

[60]  R. Kitsis,et al.  The MEK1–ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice , 2000, The EMBO journal.

[61]  K. Weber Fibrosis and hypertensive heart disease , 2000, Current opinion in cardiology.

[62]  J. Gardin,et al.  Predictors of congestive heart failure in the elderly: the Cardiovascular Health Study. , 2000, Journal of the American College of Cardiology.

[63]  M. Okabe,et al.  Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[64]  M. Weckström,et al.  Catecholamines in pericardial fluid of normotensive, spontaneously hypertensive and reserpine-treated rats. , 1999, Acta physiologica Scandinavica.

[65]  Xinmin Cao,et al.  Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK) , 1998, Oncogene.

[66]  P. Abete,et al.  Alterations in β-adrenoceptor mechanisms in the aging heart. Relationship with heart failure , 1997, Aging.

[67]  R. Weindruch,et al.  Caloric Intake and Aging , 1997 .

[68]  A. Patzak,et al.  Does low frequency power of arterial blood pressure reflect sympathetic tone? , 1995, Journal of the autonomic nervous system.

[69]  T. Lee,et al.  Transforming growth factor-beta response elements of the skeletal alpha-actin gene. Combinatorial action of serum response factor, YY1, and the SV40 enhancer-binding protein, TEF-1. , 1994, The Journal of biological chemistry.

[70]  E. Lakatta,et al.  Expression of the sarcomeric actin isogenes in the rat heart with development and senescence. , 1992, Circulation research.

[71]  T. Parker,et al.  Peptide growth factors can provoke "fetal" contractile protein gene expression in rat cardiac myocytes. , 1990, The Journal of clinical investigation.

[72]  M. Buckingham,et al.  α‐Skeletal Muscle Actin mRNA's Accumulate in Hypertrophied Adult Rat Hearts , 1986, Circulation research.

[73]  M. M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[74]  D. Zipes,et al.  Cardiovascular Disease in the Elderly , 2023, Contemporary Cardiology.

[75]  G. Poli,et al.  Alternate-day fasting protects the rat heart against age-induced inflammation and fibrosis by inhibiting oxidative damage and NF-kB activation. , 2010, Free radical biology & medicine.

[76]  犬塚 康孝 Suppression of phosphoinositide 3-kinase prevents cardiac aging in mice , 2009 .

[77]  C. Padovani,et al.  Misclassification probability as obese or lean in hypercaloric and normocaloric diet. , 2008, Biological research.

[78]  W. Elliott Regression of Electrocardiographic Left Ventricular Hypertrophy Is Associated with Less Hospitalization for Heart Failure in Hypertensive Patients , 2008 .

[79]  J. Nyman,et al.  Calorie Restriction Prevents Age-Related Trabecular Bone Loss via SIRT , 2008 .

[80]  S. McKiernan,et al.  Age-related changes in cardiac structure and function in Fischer 344 x Brown Norway hybrid rats. , 2006, American journal of physiology. Heart and circulatory physiology.

[81]  S. Clément,et al.  Correlation of alpha-skeletal actin expression, ventricular fibrosis and heart function with the degree of pressure overload cardiac hypertrophy in rats. , 2006, Experimental physiology.

[82]  David A. Kass,et al.  Age-related Changes in Venticular–Arterial Coupling: Pathophysiologic Implications , 2004, Heart Failure Reviews.

[83]  D. Roith Insulin-like Growth Factors , 2024 .

[84]  T. Ishimitsu,et al.  Effect of a hypocaloric diet on adrenomedullin and natriuretic peptides in obese patients with essential hypertension. , 2000, Journal of cardiovascular pharmacology.

[85]  Shokei Kim,et al.  Cardiac mitogen-activated protein kinase activities are chronically increased in stroke-prone hypertensive rats. , 1998, Hypertension.

[86]  R. Weindruch,et al.  Seminars in medicine of the Beth Israel Deaconess Medical Center. Caloric intake and aging. , 1997, The New England journal of medicine.

[87]  G. L. Peterson Determination of total protein. , 1983, Methods in enzymology.

[88]  G. L. Peterson [12] Determination of total protein , 1983 .