The global burden of measles in the year 2000--a model that uses country-specific indicators.

The estimation of the global burden of measles is challenging in the absence of reliable and comparable surveillance systems worldwide. A static model is described that enables estimation of measles morbidity, mortality, and disability for the year 2000 on the basis of country-specific information (i.e., demographic profile, vaccine coverage, and estimates of case-fatality ratios). This approach estimated a global incidence of 39.9 million measles cases, 777,000 deaths, and 28 million disability-adjusted life years. The World Health Organization regions of Africa and Southeast Asia had 70% of incident cases and 84% of measles-related deaths; 11 countries alone (Afghanistan, Burkina Faso, Democratic Republic of the Congo, Ethiopia, India, Indonesia, Niger, Nigeria, Pakistan, Somalia, Uganda) account for 66% of deaths. This approach quantifies the measles burden by considering country-specific indicators, which can be updated, permitting an assessment of country, regional, and global changes in the burden associated with measles infection.

[1]  L. Pelletier,et al.  Modelling the incidence of measles in Canada: an assessment of the options for vaccination policy. , 1998, Vaccine.

[2]  M. Miller.  Introducing a novel model to estimate national and global measles disease burden. , 2000, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

[3]  Gro Harlem Brundtland,et al.  Mental Health: New Understanding, New Hope , 2001 .

[4]  R. Henderson,et al.  Expanded programme on immunization. , 1988, World health statistics quarterly. Rapport trimestriel de statistiques sanitaires mondiales.

[5]  P. Strebel,et al.  Reporting efficiency during a measles outbreak in New York City, 1991. , 1993, American journal of public health.

[6]  A. Hinman,et al.  Appropriate age for measles vaccination in the United States. , 1986, Developments in biological standardization.

[7]  S. Siziya,et al.  Measles complications: the importance of their management in reducing mortality attributed to measles. , 1997, Central African Journal of Medicine.

[8]  M. Kretzschmar,et al.  The pre-vaccination epidemiology of measles, mumps and rubella in Europe: implications for modelling studies , 2000, Epidemiology and Infection.

[9]  Paul Bebbington,et al.  The World Health Report 2001 , 2001, Social Psychiatry and Psychiatric Epidemiology.

[10]  Alan D. Lopez,et al.  Global health statistics: a compendium of incidence prevalence and mortality estimates for over 200 conditions. , 1996 .

[11]  C. Paquet,et al.  Measles vaccine effectiveness in standard and early immunization strategies, Niger, 1995. , 1998, The Pediatric infectious disease journal.

[12]  P. Rota,et al.  Measles outbreaks in Micronesia, 1991 to 1994. , 1998, The Pediatric infectious disease journal.

[13]  P. Fine,et al.  The efficiency of measles and pertussis notification in England and Wales. , 1985, International journal of epidemiology.

[14]  Joshua A. Salomon,et al.  The Epidemiologic Transition Revisited: Compositional Models for Causes of Death by Age and Sex , 2002 .

[15]  Alan D. Lopez,et al.  The global burden of disease: a comprehensive assessment of mortality and disability from diseases injuries and risk factors in 1990 and projected to 2020. , 1996 .

[16]  R M May,et al.  Age-related changes in the rate of disease transmission: implications for the design of vaccination programmes , 1985, Journal of Hygiene.

[17]  Joshua A. Salomon,et al.  World mortality in 2000: life tables for 191 countries. , 2002 .

[18]  R. Eggers,et al.  First 5 years of measles elimination in southern Africa: 1996–2000 , 2002, The Lancet.

[19]  H. Whittle,et al.  Decline in measles case fatality ratio after the introduction of measles immunization in rural Senegal. , 1997, American journal of epidemiology.