Harnessing mutagenic homologous recombination for targeted mutagenesis in vivo by TaGTEAM
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[1] R. Rothstein,et al. Rad52 forms DNA repair and recombination centers during S phase , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[2] Leopold Parts,et al. Population genomics of domestic and wild yeasts , 2008 .
[3] S. Sarkar,et al. On fluctuation analysis: a new, simple and efficient method for computing the expected number of mutants , 2004, Genetica.
[4] D. Gordenin,et al. A single-strand specific lesion drives MMS-induced hyper-mutability at a double-strand break in yeast. , 2010, DNA repair.
[5] F. Arnold,et al. Directed enzyme evolution. , 2001, Current opinion in biotechnology.
[6] A. Malkova,et al. Defective Resection at DNA Double-Strand Breaks Leads to De Novo Telomere Formation and Enhances Gene Targeting , 2010, PLoS genetics.
[7] Seong-Il Lee,et al. Identification and Use of Zinc Finger Transcription Factors That Increase Production of Recombinant Proteins in Yeast and Mammalian Cells , 2008, Biotechnology progress.
[8] Gregory Stephanopoulos,et al. Combinatorial engineering of microbes for optimizing cellular phenotype. , 2008, Current opinion in chemical biology.
[9] M. Wabl,et al. Directed molecular evolution by somatic hypermutation. , 2004, Protein engineering, design & selection : PEDS.
[10] Manel Camps,et al. Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[11] B. Shafer,et al. The roles of REV3 and RAD57 in double-strand-break-repair-induced mutagenesis of Saccharomyces cerevisiae. , 2002, Genetics.
[12] F. M. Stewart. Fluctuation tests: how reliable are the estimates of mutation rates? , 1994, Genetics.
[13] G. Lucchini,et al. The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. , 2000, Genes & development.
[14] G. Stephanopoulos,et al. Engineering Yeast Transcription Machinery for Improved Ethanol Tolerance and Production , 2006, Science.
[15] R. Tsien,et al. Evolution of new nonantibody proteins via iterative somatic hypermutation. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[16] J. Collins,et al. Combinatorial promoter design for engineering noisy gene expression , 2007, Proceedings of the National Academy of Sciences.
[17] L. Rasmussen,et al. Generation of a strong mutator phenotype in yeast by imbalanced base excision repair. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[18] D. Gordenin,et al. Hypermutability of Damaged Single-Strand DNA Formed at Double-Strand Breaks and Uncapped Telomeres in Yeast Saccharomyces cerevisiae , 2008, PLoS genetics.
[19] P. Foster,et al. Methods for determining spontaneous mutation rates. , 2006, Methods in enzymology.
[20] K. Hammer,et al. The Sequence of Spacers between the Consensus Sequences Modulates the Strength of Prokaryotic Promoters , 1998, Applied and Environmental Microbiology.
[21] A. Das,et al. Viral Evolution as a Tool to Improve the Tetracycline-regulated Gene Expression System* , 2004, Journal of Biological Chemistry.
[22] D. Sherratt,et al. Spatial and temporal organization of replicating Escherichia coli chromosomes , 2003, Molecular microbiology.
[23] Robert P. Davey,et al. Population genomics of domestic and wild yeasts , 2008, Nature.
[24] R. D. Gietz,et al. Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method. , 2002, Methods in enzymology.
[25] J. Rine,et al. Overlapping roles of the spindle assembly and DNA damage checkpoints in the cell-cycle response to altered chromosomes in Saccharomyces cerevisiae. , 2002, Genetics.
[26] Brian F. Pfleger,et al. Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes , 2006, Nature Biotechnology.
[27] Andrew W. Murray,et al. Estimating the Per-Base-Pair Mutation Rate in the Yeast Saccharomyces cerevisiae , 2008, Genetics.
[28] Dana Carroll,et al. Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases. , 2002, Genetics.
[29] R. B. Caldwell,et al. Protein evolution by hypermutation and selection in the B cell line DT40 , 2007, Nucleic acids research.
[30] Susan Carpenter,et al. Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes , 2011, Nucleic acids research.
[31] J. Tainer,et al. Excision of cytosine and thymine from DNA by mutants of human uracil‐DNA glycosylase. , 1996, The EMBO journal.
[32] C. Lawrence,et al. Novel mutagenic properties of abasic sites in Saccharomyces cerevisiae. , 1995, Journal of molecular biology.
[33] J. Haber,et al. Sgs1 and Exo1 Redundantly Inhibit Break-Induced Replication and De Novo Telomere Addition at Broken Chromosome Ends , 2010, PLoS genetics.
[34] S. Boiteux,et al. Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae. , 2004, DNA repair.
[35] Gilles Charvin,et al. A Microfluidic Device for Temporally Controlled Gene Expression and Long-Term Fluorescent Imaging in Unperturbed Dividing Yeast Cells , 2008, PloS one.
[36] T. Ellenberger,et al. Dissecting the Broad Substrate Specificity of Human 3-Methyladenine-DNA Glycosylase* , 2004, Journal of Biological Chemistry.
[37] Mads Kærn,et al. Noise in eukaryotic gene expression , 2003, Nature.
[38] Srinivasan Chandrasegaran,et al. Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells , 2005, Nucleic acids research.
[39] Vasco M. Barreto,et al. Activation-induced deaminase: controversies and open questions. , 2005, Trends in immunology.
[40] A. Børresen-Dale,et al. Mutational Processes Molding the Genomes of 21 Breast Cancers , 2012, Cell.
[41] Keith E. J. Tyo,et al. Expanding the metabolic engineering toolbox: more options to engineer cells. , 2007, Trends in biotechnology.
[42] Farren J. Isaacs,et al. Programming cells by multiplex genome engineering and accelerated evolution , 2009, Nature.
[43] Steven A. Roberts,et al. Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions. , 2012, Molecular cell.
[44] G. Stephanopoulos,et al. Tuning genetic control through promoter engineering. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[45] M. Lomax,et al. Delayed repair of radiation induced clustered DNA damage: Friend or foe? , 2011, Mutation research.
[46] J. Strathern,et al. A role for REV3 in mutagenesis during double-strand break repair in Saccharomyces cerevisiae. , 1997, Genetics.
[47] David R. Liu,et al. A System for the Continuous Directed Evolution of Biomolecules , 2011, Nature.
[48] D. Schaffer,et al. Directed evolution of adeno-associated virus yields enhanced gene delivery vectors , 2006, Nature Biotechnology.
[49] L. Symington,et al. Double-strand break end resection and repair pathway choice. , 2011, Annual review of genetics.
[50] A. N. van den Pol,et al. Viral Mutagenesis as a Means for Generating Novel Proteins , 2009, Journal of Virology.
[51] Single-chain Tet transregulators. , 2003, Nucleic acids research.
[52] Dana Carroll,et al. Targeted mutagenesis using zinc-finger nucleases in Arabidopsis. , 2005, Proceedings of the National Academy of Sciences of the United States of America.