Treatment of anogenital warts in an 18-month-old girl with 5% imiquimod cream.

Possible modes of transmission of the human papilloma virus (HPV) in children include perinatal transmission, sexual transmission, or extragenital contact. Conventional treatment options with chemical and physical destruction methods can be difficult and painful and often require general anesthesia. Imiquimod is a topically active immunomodulatory agent that has been shown to successfully treat pediatric anogenital warts. We report on a case of extensive anogenital warts in a 18-month-old girl who was successfully treated with topical 5% imiquimod cream.

[1]  A. Black,et al.  Imiquimod 5% cream treatment for rapidly progressive genital condyloma in a 3-year-old girl. , 2012, Journal of pediatric and adolescent gynecology.

[2]  J. English,et al.  Evidence-based treatment and prevention of external genital warts in female pediatric and adolescent patients. , 2012, Journal of pediatric and adolescent gynecology.

[3]  C. Trimble,et al.  Human papillomavirus in infants: transmission, prevalence, and persistence. , 2012, Journal of pediatric and adolescent gynecology.

[4]  T. Fuchigami,et al.  Effectiveness of imiquimod 5% cream for treatment of perianal warts in a 28‐month‐old child , 2011, Pediatrics international : official journal of the Japan Pediatric Society.

[5]  C. Woods,et al.  Venereal warts in children. , 2011, Pediatrics in review.

[6]  Paulo Ricardo Criado,et al.  Tratamento do papiloma vírus humano na infância com creme de imiquimode a 5 , 2010 .

[7]  P. Criado,et al.  Treatment of human papillomavirus in childhood with imiquimod 5% cream. , 2010, Anais brasileiros de dermatologia.

[8]  D. Morrell,et al.  The management of condyloma acuminata in the pediatric population. , 2009, Pediatric annals.

[9]  T. Aoki,et al.  Effectiveness of imiquimod 5% cream for treatment of extensive anogenital warts in a seven-year-old child. , 2007, The Pediatric infectious disease journal.

[10]  C. Woods Sexually transmitted diseases in prepubertal children: mechanisms of transmission, evaluation of sexually abused children, and exclusion of chronic perinatal viral infections. , 2005, Seminars in pediatric infectious diseases.

[11]  C. Woods,et al.  Anogenital and Respiratory Tract Human Papillomavirus Infections Among Children: Age, Gender, and Potential Transmission Through Sexual Abuse , 2005, Pediatrics.

[12]  T. Pniewski,et al.  Imiquimod is Highly Effective for Extensive, Hyperproliferative Condyloma in Children , 2003, Pediatric dermatology.

[13]  M. Mercurio,et al.  Treatment of Human Papilloma Virus in a 6‐Month‐Old Infant with Imiquimod 5% Cream , 2001, Pediatric dermatology.

[14]  P. Wilkinson Successful treatment of perianal warts in a child with 5% imiquimod cream , 2001, The Journal of dermatological treatment.

[15]  L. Frasier Human papillomavirus infections in children. , 1994, Pediatric annals.