Recent primary transnasal surgical outcomes associated with intraoperative growth hormone measurement in acromegaly

Since 1983, we have measured GH intraoperatively to improve the surgical outcome for acromegalic patients with GH secreting pituitary adenomas. Here, we present the recent results of primary surgery in patients with acromegaly to examine the effect of improved surgical techniques and experience.

[1]  D. Lüdecke,et al.  Recent results of secondary transnasal surgery for residual or recurring acromegaly. , 1998, Neurosurgery.

[2]  M. Losa,et al.  Surgical therapy of pituitary adenomas. , 1996, Metabolism: clinical and experimental.

[3]  A. Beckers,et al.  Presurgical Octreotide: treatment in acromegaly. , 1993, Metabolism: Clinical and Experimental.

[4]  M. Losa,et al.  Assessment of growth hormone (GH) plasma clearance rate, half-life, and volume of distribution in acromegalic patients: the combined GH-octreotide infusion. , 1995, The Journal of clinical endocrinology and metabolism.

[5]  D. Lüdecke,et al.  Pituitary surgery in elderly patients with acromegaly. , 1995, Neurosurgery.

[6]  J. Veldhuis,et al.  Growth hormone secretion in recently operated acromegalic patients. , 1994, The Journal of clinical endocrinology and metabolism.

[7]  K. Schärer,et al.  Alterations in growth hormone secretion and clearance in peripubertal boys with chronic renal failure and after renal transplantation. Cooperative Study Group of Pubertal development in Chronic Renal Failure. , 1994, The Journal of clinical endocrinology and metabolism.

[8]  B. Scheithauer,et al.  Results of surgical treatment for growth hormone-secreting pituitary adenomas. , 1993, Journal of neurosurgery.

[9]  R. Clayton,et al.  An audit of outcome of treatment in acromegaly. , 1993, The Quarterly journal of medicine.

[10]  N. Watts,et al.  Transsphenoidal adenomectomy for growth hormone-secreting pituitary adenomas in acromegaly: outcome analysis and determinants of failure. , 1993, Journal of neurosurgery.

[11]  J. Honegger,et al.  Surgical management of acromegaly. , 1992, Endocrinology and metabolism clinics of North America.

[12]  M. Vance,et al.  Temporal structure of in vivo growth hormone secretory events in humans. , 1991, The American journal of physiology.

[13]  M. Losa,et al.  Evaluation of selective transsphenoidal adenomectomy by endocrinological testing and somatomedin-C measurement in acromegaly. , 1989, Journal of neurosurgery.

[14]  D. Ross,et al.  Results of transsphenoidal microsurgery for growth hormone-secreting pituitary adenoma in a series of 214 patients. , 1988, Journal of neurosurgery.

[15]  F. Roelfsema,et al.  PLASMA GROWTH HORMONE HALF‐LIFE AFTER SELECTIVE REMOVAL OF ADENOMA IN ACROMEGALICS DETERMINES THE OUTCOME OF SURGERY , 1988, Clinical endocrinology.

[16]  A. Landolt,et al.  Surgical Treatment of Acromegaly , 1988 .

[17]  H. Herrmann,et al.  Improved intraoperative GH-RIA in acromegaly , 1987 .

[18]  Y. Shishiba,et al.  Decrease in human growth hormone (HGH) levels during transsphenoidal surgery for acromegaly as a guide for prognosis. , 1985, Endocrinologia japonica.

[19]  J. Hassoun,et al.  Transsphenoidal surgery for acromegaly--long-term results in 100 patients. , 1985, Surgical neurology.

[20]  P. Gorden,et al.  Plasma clearance of intravenously administered pituitary human growth hormone: gel filtration studies of heterogeneous components. , 1985, The Journal of clinical endocrinology and metabolism.

[21]  R. Fahlbusch,et al.  INFLUENCE OF PREOPERATIVE BROMOCRIPTINE THERAPY ON SUCCESS OF SURGERY FOR MICROPROLACTINOMA , 1984, The Lancet.

[22]  R. Katakura,et al.  Rapid radioimmunoassay of plasma GH and its application to the judgement of surgical results in patients with acromegaly. , 1984, The Tohoku journal of experimental medicine.

[23]  H. Quabbe.  TREATMENT OF ACROMEGALY BY TRANS‐SPHENOIDAL OPERATION, 90‐YTTRIUM IMPLANTATION AND BROMOCRIPTINE: RESULTS IN 230 PATIENTS , 1982 .

[24]  Quabbe Hj.  TREATMENT OF ACROMEGALY BY TRANS‐SPHENOIDAL OPERATION, 90‐YTTRIUM IMPLANTATION AND BROMOCRIPTINE: RESULTS IN 230 PATIENTS , 1982 .

[25]  W. Vanderlaan,et al.  The biological half-life of human growth hormone and a biologically active 20,000-dalton variant in mouse blood. , 1982, Endocrine research communications.

[26]  C. Wilson,et al.  Transsphenoidal microsurgical removal of 250 pituitary adenomas. , 1978, Journal of neurosurgery.

[27]  P. Steins,et al.  PERIOPERATIVE GROWTH HORMONE STUDIES DURING SELECTIVE ADENOMECTOMY IN ACROMEGALY , 1975 .

[28]  D. Cook,et al.  Serial plasma growth hormone concentration during selective removal of pituitary tumors in acromegaly. , 1974, Journal of neurosurgery.