In Vitro Synthesis of Modified RNA for Cardiac Gene Therapy.

[1]  K. Kaur,et al.  mRNA-Based Protein Replacement Therapy for the Heart , 2018, Molecular therapy : the journal of the American Society of Gene Therapy.

[2]  Neha Singh,et al.  Ablation of a Single N-Glycosylation Site in Human FSTL 1 Induces Cardiomyocyte Proliferation and Cardiac Regeneration , 2018, Molecular therapy. Nucleic acids.

[3]  R. Hajjar,et al.  Optimizing Cardiac Delivery of Modified mRNA. , 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

[4]  N. Sultana,et al.  Synthesis of Modified mRNA for Myocardial Delivery. , 2017, Methods in molecular biology.

[5]  Özlem Türeci,et al.  mRNA-based therapeutics — developing a new class of drugs , 2014, Nature Reviews Drug Discovery.

[6]  B. Neyns,et al.  A phase IB study on intravenous synthetic mRNA electroporated dendritic cell immunotherapy in pretreated advanced melanoma patients. , 2013, Annals of oncology : official journal of the European Society for Medical Oncology.

[7]  Ronald A. Li,et al.  Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction , 2013, Nature Biotechnology.

[8]  M. Idzko,et al.  Modified Foxp3 mRNA protects against asthma through an IL-10-dependent mechanism. , 2013, The Journal of clinical investigation.

[9]  Yuhua Wang,et al.  Systemic delivery of modified mRNA encoding herpes simplex virus 1 thymidine kinase for targeted cancer gene therapy. , 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

[10]  W. Rottbauer,et al.  Successful Use of mRNA-Nucleofection for Overexpression of Interleukin-10 in Murine Monocytes/Macrophages for Anti-inflammatory Therapy in a Murine Model of Autoimmune Myocarditis , 2012, Journal of the American Heart Association.

[11]  D. Weissman,et al.  Increased Erythropoiesis in Mice Injected With Submicrogram Quantities of Pseudouridine-containing mRNA Encoding Erythropoietin , 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

[12]  R. McIvor.  Therapeutic delivery of mRNA: the medium is the message. , 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

[13]  H. Rammensee,et al.  Intradermal vaccinations with RNA coding for TAA generate CD8+ and CD4+ immune responses and induce clinical benefit in vaccinated patients. , 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

[14]  J. Rosenecker,et al.  Expression of therapeutic proteins after delivery of chemically modified mRNA in mice , 2011, Nature Biotechnology.

[15]  R. Scott McIvor.  Therapeutic Delivery of mRNA: The Medium Is the Message. , 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

[16]  C. Fathman,et al.  A short pulse of IL-4 delivered by DCs electroporated with modified mRNA can both prevent and treat autoimmune diabetes in NOD mice. , 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

[17]  H. Rammensee,et al.  Direct Injection of Protamine-protected mRNA: Results of a Phase 1/2 Vaccination Trial in Metastatic Melanoma Patients , 2009, Journal of immunotherapy.

[18]  Hiroki Kato,et al.  Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability. , 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

[19]  T. Tagawa,et al.  Bax mRNA therapy using cationic liposomes for human malignant melanoma , 2008, Journal of Gene Medicine.

[20]  J. Sampson,et al.  Selective modification of antigen-specific T cells by RNA electroporation. , 2008, Human gene therapy.

[21]  Donna Niedzwiecki,et al.  Telomerase mRNA-Transfected Dendritic Cells Stimulate Antigen-Specific CD8+ and CD4+ T Cell Responses in Patients with Metastatic Prostate Cancer 1 , 2005, The Journal of Immunology.

[22]  E. Gilboa,et al.  Immunotherapy with Autologous, Human Dendritic Cells Transfected with Carcinoembryonic Antigen mRNA , 2003, Cancer investigation.

[23]  E. Gilboa,et al.  The feasibility and safety of immunotherapy with dendritic cells loaded with CEA mRNA following neoadjuvant chemoradiotherapy and resection of pancreatic cancer , 2002, International journal of gastrointestinal cancer.

[24]  E. Gilboa,et al.  Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors. , 2002, The Journal of clinical investigation.