A preliminary study for the establishment of a reference interval for vitamin B12 in China after performance verification of a second‐generation ECLIA kit

The second‐generation electrochemiluminescence immunoassay (ECLIA) kit of vitamin B12 is widely used in clinical laboratories, and the establishment of a reference interval (RI) is essential to provide the basis for clinical monitoring. The purpose of this study was to establish a laboratory RI for vitamin B12 in China and at the same time verify the method performance of the second‐generation kit.

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