The endothelin axis: emerging role in cancer
暂无分享,去创建一个
[1] S. Shibata,et al. A selective endothelin ETA antagonist, BQ-123, inhibits125I-endothelin-1 (125I-ET-1) binding to human meningiomas and antagonizes ET-1-induced proliferation of meningioma cells , 1994, Cellular and Molecular Neurobiology.
[2] J. Nelson,et al. Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: a randomized, phase II, placebo-controlled trial. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[3] F. Balkwill,et al. Endothelin-2 is a hypoxia-induced autocrine survival factor for breast tumor cells. , 2002, Molecular cancer therapeutics.
[4] N. Perico,et al. New therapeutics that antagonize endothelin: promises and frustrations , 2002, Nature Reviews Drug Discovery.
[5] P. Natali,et al. Growth inhibition of cervix carcinoma cells in vivo by endothelin A receptor blockade. , 2002, Cancer research.
[6] F. Spinella,et al. ABT-627, a potent endothelin receptor A antagonist, inhibits ovarian carcinoma growth in vitro. , 2002, Clinical science.
[7] F. Spinella,et al. Endothelin-1 promotes proteolytic activity of ovarian carcinoma. , 2002, Clinical science.
[8] F. Spinella,et al. Endothelin-1 Induces Vascular Endothelial Growth Factor by Increasing Hypoxia-inducible Factor-1α in Ovarian Carcinoma Cells* , 2002, The Journal of Biological Chemistry.
[9] G. Mundy. Metastasis: Metastasis to bone: causes, consequences and therapeutic opportunities , 2002, Nature Reviews Cancer.
[10] J. Nelson,et al. Atrasentan, an endothelin-receptor antagonist for refractory adenocarcinomas: safety and pharmacokinetics. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[11] Jeroen van derBoon. New drug slows prostate-cancer progression. , 2002 .
[12] F. Spinella,et al. Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation. , 2002, Molecular pharmacology.
[13] J. van der Boon. New drug slows prostate-cancer progression. , 2002, The Lancet. Oncology.
[14] F. Spinella,et al. Endothelin-1 induces tumor proteinase activation and invasiveness of ovarian carcinoma cells. , 2001, Cancer research.
[15] G. Burnstock,et al. Increased endothelin-1 in colorectal cancer and reduction of tumour growth by ET A receptor antagonism , 2001, British Journal of Cancer.
[16] G. Filippatos,et al. Regulation of apoptosis by vasoactive peptides. , 2001, American journal of physiology. Lung cellular and molecular physiology.
[17] S. Kitazawa,et al. Expression of endothelin receptor a associated with prostate cancer progression. , 2001, The Journal of urology.
[18] A. Albini,et al. Endothelin receptor blockade inhibits proliferation of Kaposi's sarcoma cells. , 2001, The American journal of pathology.
[19] F. Pinet,et al. Modulation of human colon tumor-stromal interactions by the endothelin system. , 2000, The American journal of pathology.
[20] T. Lüscher,et al. Endothelins and Endothelin Receptor Antagonists: Therapeutic Considerations for a Novel Class of Cardiovascular Drugs , 2000, Circulation.
[21] P. Natali,et al. Role of endothelin-1 in neovascularization of ovarian carcinoma. , 2000, The American journal of pathology.
[22] F. Pinet,et al. Endothelin receptor blockade potentiates FasL-induced apoptosis in colon carcinoma cells via the protein kinase C-pathway. , 2000, Journal of cardiovascular pharmacology.
[23] G. Taraboletti,et al. Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo. , 2000, The American journal of pathology.
[24] A. Venuti,et al. Expression of endothelin 1 and endothelin A receptor in HPV‐associated cervical carcinoma: new potential targets for anticancer therapy , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[25] K. Catt,et al. Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells. , 2000, Cancer research.
[26] Y. M. Yang,et al. Endothelin-1 from prostate cancer cells is enhanced by bone contact which blocks osteoclastic bone resorption , 2000, British Journal of Cancer.
[27] J. Nelson,et al. Endothelium‐derived factors as paracrine mediators of prostate cancer progression , 2000, The Prostate.
[28] T. Guise. Molecular mechanisms of osteolytic bone metastases , 2000, Cancer.
[29] J. R. Wu-wong,et al. Extracellular signal-regulated kinases are involved in the antiapoptotic effect of endothelin-1. , 2000, The Journal of pharmacology and experimental therapeutics.
[30] L. Juillerat-Jeanneret,et al. Endothelin receptor blockade potentiates FasL‐induced apoptosis in rat colon carcinoma cells , 2000, International journal of cancer.
[31] P. Woll,et al. Studies on the expression of endothelin, its receptor subtypes, and converting enzymes in lung cancer and in human bronchial epithelium. , 2000, American journal of respiratory cell and molecular biology.
[32] Chakrabarti,et al. Augmented expression of endothelin‐1, endothelin‐3 and the endothelin‐B receptor in breast carcinoma , 2000, Histopathology.
[33] M. Clozel. Endothelin receptor antagonists: current status and perspectives. , 2000, Journal of cardiovascular pharmacology.
[34] M. Mcmillen,et al. Endothelins are angiogenic. , 2000, Journal of cardiovascular pharmacology.
[35] T. Masaki. The endothelin family: an overview. , 2000, Journal of cardiovascular pharmacology.
[36] E. Fearon,et al. Cancer progression , 1999, Current Biology.
[37] P. Patterson,et al. An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivo. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[38] J. Smyth,et al. Paracrine regulation of ovarian cancer by endothelin. , 1999, European journal of cancer.
[39] T. Yoneda,et al. Factors regulating the growth of metastatic cancer in bone. , 1999, Endocrine-related cancer.
[40] J. Eberle,et al. Downregulation of endothelin B receptor in human melanoma cell lines parallel to differentiation genes. , 1999, The Journal of investigative dermatology.
[41] J. Nelson,et al. The Role of the Endothelin Axis in Prostate Cancer , 1999 .
[42] J. Nelson,et al. New bone formation in an osteoblastic tumor model is increased by endothelin-1 overexpression and decreased by endothelin A receptor blockade. , 1999, Urology.
[43] J. Nelson,et al. ENDOTHELIN AXIS EXPRESSION IN RENAL CELL CARCINOMA , 1999 .
[44] R. Goldie. ENDOTHELINS IN HEALTH AND DISEASE: AN OVERVIEW , 1999, Clinical and experimental pharmacology & physiology.
[45] P. Natali,et al. Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth. , 1999, Cancer research.
[46] K. Catt,et al. Endothelins as Autocrine Regulators of Tumor Cell Growth , 1998, Trends in Endocrinology & Metabolism.
[47] J. Pickard,et al. Expression of endothelin(A) receptors in human gliomas and meningiomas, with high affinity for the selective antagonist PD156707. , 1998, Neurosurgery.
[48] H. Krum,et al. The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. Bosentan Hypertension Investigators. , 1998, The New England journal of medicine.
[49] H. Lepor,et al. Endothelin‐1 production and agonist activities in cultured prostate‐derived cells: Implications for regulation of endothelin bioactivity and bioavailability in prostatic hyperplasia , 1998, The Prostate.
[50] Catherine Magill,et al. Neutral endopeptidase 24.11 loss in metastatic human prostate cancer contributes to androgen-independent progression , 1998, Nature Medicine.
[51] J. R. Wu-wong,et al. Endothelin attenuates apoptosis in human smooth muscle cells. , 1997, The Biochemical journal.
[52] M. Shichiri,et al. Endothelin-1 as an autocrine/paracrine apoptosis survival factor for endothelial cells. , 1997, Hypertension.
[53] S. Langdon,et al. Endothelin expression and responsiveness in human ovarian carcinoma cell lines. , 1997, European journal of cancer.
[54] J. Brooks,et al. Methylation of the 5' CpG island of the endothelin B receptor gene is common in human prostate cancer. , 1997, Cancer research.
[55] M. Mihm,et al. Decreased ET(B) receptor expression in human metastatic melanoma cells. , 1996, Biochemical and biophysical research communications.
[56] S. Magnuson,et al. Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer. , 1996, Cancer research.
[57] A. Ullrich,et al. Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors , 1996, Nature.
[58] M. Mattei,et al. Organization of the Gene Encoding the Human Endothelin-converting Enzyme (ECE-1) (*) , 1995, The Journal of Biological Chemistry.
[59] A. Weindl,et al. Expression and localization of endothelin-1 and endothelin receptors in human meningiomas. Evidence for a role in tumoral growth. , 1995, The Journal of clinical investigation.
[60] K. Catt,et al. Autocrine actions of endothelin-1 as a growth factor in human ovarian carcinoma cells. , 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.
[61] J. Nelson,et al. Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostate , 1995, Nature Medicine.
[62] H. Wu,et al. Identification and characterization of endothelin receptors on rat osteoblastic osteosarcoma cells: down-regulation by 1,25-dihydroxy-vitamin D3. , 1995, Molecular pharmacology.
[63] E. Levin. Mechanisms of disease : endothelins , 1995 .
[64] T. Opgenorth. Endothelin receptor antagonism. , 1995, Advances in pharmacology.
[65] J. Polak,et al. Localization and Characterization of Endothelin‐1 Receptor Binding in the Blood Vessels of Human Pulmonary Tumors , 1995, Journal of cardiovascular pharmacology.
[66] A. Weindl,et al. Cellular Localization of Endothelin Receptor mRNAs (ETA and ETB) in Brain Tumors and Normal Human Brain , 1995, Journal of cardiovascular pharmacology.
[67] M. Zamora,et al. Human melanoma cells express functional endothelin-1 receptors. , 1994, Biochemical and biophysical research communications.
[68] N. Brière,et al. Growth regulatory properties of endothelins , 1993, Peptides.
[69] M. Ogawa,et al. A large amount of endothelin-1 is present in human breast cancer tissues. , 1991, Research communications in chemical pathology and pharmacology.
[70] G. Rubanyi,et al. Endothelins , 1991, The Lancet.
[71] B. Corrin,et al. Detection of endothelin immunoreactivity and mRNA in pulmonary tumours , 1990, The Journal of pathology.
[72] R. Eddy,et al. Structural organization and chromosomal assignment of the gene encoding endothelin. , 1989, The Journal of biological chemistry.