Magnetic resonance imaging of pituitary adenomas

Today, MR is the only method needed for the morphological investigation of endocrine-active pituitary adenomas. In acromegaly and Cushing’s syndrome, the therapeutic attitude is directly dictated by MR data. We present the MR aspect of pituitary adenomas according to size, sex, age, endocrine activity and a few particular conditions such as hemorrhagic pituitary adenomas, pituitary adenomas during pregnancy, cavernous sinus invasion and postsurgical changes. When an intrasellar mass extending out of the sella turcica is detected, the goal of the MR examination is to indicate precisely the origin of the tumor, its extension in relation to the various surrounding structures, its structure and its enhancement in order to help in the differential diagnosis. Demonstration of very small pituitary adenomas remains a challenge. When SE T1- and Turbo SE T2-weighted sequences are non-diagnostic, enhanced imaging becomes mandatory; half-dose gadolinium injection, delayed sequence, dynamic imaging can be of some help.

[1]  J. Bishop,et al.  Detection of pituitary microadenomas: comparison of dynamic keyhole fast spin-echo, unenhanced, and conventional contrast-enhanced MR imaging. , 1994, AJR. American journal of roentgenology.

[2]  P. Hudgins,et al.  Pituitary adenoma: correlation of half-dose gadolinium-enhanced MR imaging with surgical findings in 26 patients. , 1991, Radiology.

[3]  P. Lundin,et al.  Long-term octreotide therapy in growth hormone-secreting pituitary adenomas: evaluation with serial MR. , 1997, AJNR. American journal of neuroradiology.

[4]  M. Teng,et al.  The pituitary mass after transsphenoidal hypophysectomy. , 1988, AJNR. American journal of neuroradiology.

[5]  J. Doppman,et al.  Gadolinium DTPA enhanced MR imaging of ACTH-secreting microadenomas of the pituitary gland. , 1988, Journal of computer assisted tomography.

[6]  N. Colombo,et al.  MR of corticotropin-secreting pituitary microadenomas. , 1994, AJNR. American journal of neuroradiology.

[7]  H. Imhof,et al.  Pituitary adenomas: findings of postoperative MR imaging. , 1992, Radiology.

[8]  C. Matula,et al.  Pituitary adenomas with parasellar invasion. , 1991, Acta neurochirurgica. Supplementum.

[9]  B. Brooks,et al.  MR imaging of the ectopic bright signal of posterior pituitary regeneration. , 1989, AJNR. American journal of neuroradiology.

[10]  K. Bergström,et al.  Macroprolactinomas: serial MR imaging in long-term bromocriptine therapy. , 1992, AJNR. American journal of neuroradiology.

[11]  P. Davis,et al.  MR imaging of pituitary adenoma: CT, clinical, and surgical correlation. , 1987, AJR. American journal of roentgenology.

[12]  W. Gorczyca,et al.  Pituitary microadenomas: early enhancement with dynamic CT--implications of arterial blood supply and potential importance. , 1993, Radiology.

[13]  T. H. Newton,et al.  MR imaging of cavernous sinus involvement by pituitary adenomas. , 1988, AJR. American journal of roentgenology.

[14]  K. Post,et al.  Symptoms of pituitary apoplexy rapidly reversed with bromocriptine. Case report. , 1996, Journal of neurosurgery.

[15]  T. H. Newton,et al.  Pituitary adenomas: high-resolution MR imaging at 1.5 T. , 1986, Radiology.

[16]  J. Malko,et al.  Gadolinium-DTPA and MR imaging of pituitary adenoma: a preliminary report. , 1987, AJNR. American journal of neuroradiology.

[17]  A. Elster,et al.  Modern imaging of the pituitary. , 1993, Radiology.

[18]  C. Zee,et al.  Cavernous sinus invasion by pituitary adenomas. , 1985, AJR. American journal of roentgenology.

[19]  A. J. Kumar,et al.  Pituitary adenomas: possible role of bromocriptine in intratumoral hemorrhage. , 1989, Radiology.

[20]  J. Dietemann,et al.  CT follow-up of microprolactinomas during bromocriptine-induced pregnancy , 2004, Neuroradiology.