Shear properties of human brain tissue.

The objective of this study was to determine a relationship between shear stress and strain for human brain tissue by performing transient, single-pulse, high-rate, shear displacement tests. A constant velocity, parallel plate shear test device was designed and fabricated. This equipment generated constant rate shear strains in cylindrical tissue samples mounted between the shear plates. The transverse reaction force at the upper end of the sample was measured during the event with a sensitive quartz piezoelectric force transducer, thus obtaining the force associated with the displacement versus time ramp. Shear tests were performed on 125 tissue samples taken from twelve fresh cadaver brain specimens. The average true shear stress and finite strain were calculated. A nonlinear, viscoelastic, standard solid model was fit to the constant rate test data and the material constants were determined.

[1]  Claude Tarriere,et al.  Development of a F.E.M. of the human head according to a specific test protocol , 1992 .

[2]  Irving H. Shames.  Elastic and inelastic stress analysis , 1991 .

[3]  T A Gennarelli,et al.  Physical model simulations of brain injury in the primate. , 1990, Journal of biomechanics.

[4]  J. W. Melvin,et al.  Toward a biomechanical criterion for functional brain injury , 1989 .

[5]  Y. Fung,et al.  Biomechanics: Mechanical Properties of Living Tissues , 1981 .

[6]  James H. McElhaney,et al.  Handbook of human tolerance , 1976 .

[7]  C Ljung,et al.  A model for brain deformation due to rotation of the skull. , 1975, Journal of biomechanics.

[8]  G N Bycroft.  Mathematical model of a head subjected to an angular acceleration. , 1973, Journal of biomechanics.

[9]  L. Shuck,et al.  Rheological Response of Human Brain Tissue in Shear , 1972 .

[10]  H C Wang,et al.  A mathematical model for the determination of viscoelastic behavior of brain in vivo. I. Oscillatory response. , 1972, Journal of biomechanics.

[11]  F. J. Lockett,et al.  Nonlinear viscoelastic solids , 1972 .

[12]  A K Ommaya,et al.  A comparison of the elasticity of live, dead, and fixed brain tissue. , 1970, Journal of biomechanics.

[13]  Joseph L. Fleiss,et al.  Estimating the magnitude of experimental effects. , 1969 .

[14]  J. Melvin,et al.  Dynamic mechanical properties of human brain tissue. , 1969, Journal of biomechanics.

[15]  Y. Fung.  Foundations of solid mechanics , 1965 .