p38 MAP-kinases pathway regulation, function and role in human diseases.

[1]  A. Moon,et al.  TGF-β-induced transcriptional activation of MMP-2 is mediated by activating transcription factor (ATF)2 in human breast epithelial cells , 2007 .

[2]  J. Kyriakis.  Faculty Opinions recommendation of Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation. , 2007 .

[3]  E. Wagner,et al.  Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38α in abrogating myoblast proliferation , 2007, The EMBO journal.

[4]  J. Inazawa,et al.  A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity , 2007, Oncogene.

[5]  Gabriella De Vita,et al.  p38α MAP Kinase as a Sensor of Reactive Oxygen Species in Tumorigenesis , 2007 .

[6]  Mei Zhang,et al.  Involvement of integrins, MAPK, and NF-kappaB in regulation of the shear stress-induced MMP-9 expression in endothelial cells. , 2007, Biochemical and biophysical research communications.

[7]  A. Cuadrado,et al.  p38alpha MAP kinase as a sensor of reactive oxygen species in tumorigenesis. , 2007, Cancer cell.

[8]  Eun-sook Kim,et al.  TGF-beta-induced transcriptional activation of MMP-2 is mediated by activating transcription factor (ATF)2 in human breast epithelial cells. , 2007, Cancer letters.

[9]  P. Cohen,et al.  CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPK-MAPKAP-K2-HSP27 pathway. , 2006, Cellular signalling.

[10]  J. Richardson,et al.  MAPK-activated Protein Kinase 2 Deficiency in Microglia Inhibits Pro-inflammatory Mediator Release and Resultant Neurotoxicity , 2006, Journal of Biological Chemistry.

[11]  A. Shah,et al.  ctivation of p 38 Mitogen-Activated rotein Kinase Contributes to the Early ardiodepressant Action of Tumor Necrosis Factor , 2006 .

[12]  S. Alkan,et al.  p38gamma mitogen-activated protein kinase integrates signaling crosstalk between Ras and estrogen receptor to increase breast cancer invasion. , 2006, Cancer research.

[13]  J. Gogusev,et al.  Protein tyrosine kinase and p38 MAP kinase pathways are involved in stimulation of matrix metalloproteinase-9 by TNF-α in human monocytes , 2006 .

[14]  G. Schreiner,et al.  Selective inhibition of p38alpha MAPK improves cardiac function and reduces myocardial apoptosis in rat model of myocardial injury. , 2006, American journal of physiology. Heart and circulatory physiology.

[15]  J. Huot,et al.  Dysregulation of the endothelial cellular response to oxidative stress in cancer , 2006, Molecular carcinogenesis.

[16]  R. Bergan,et al.  MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer , 2006, Oncogene.

[17]  K. Umezawa,et al.  Conophylline: a novel differentiation inducer for pancreatic beta cells. , 2006, The international journal of biochemistry & cell biology.

[18]  Jianfei Yang,et al.  Selective Requirement of p38α MAPK in Cytokine-Dependent, but Not Antigen Receptor-Dependent, Th1 Responses1 , 2006, The Journal of Immunology.

[19]  D. Bulavin,et al.  Cell Cycling through Cdc25A: Transducer of Cytokine Proliferative Signals , 2006, Cell cycle.

[20]  M. Crompton,et al.  Bax translocates to mitochondria of heart cells during simulated ischaemia: involvement of AMP-activated and p38 mitogen-activated protein kinases. , 2006, The Biochemical journal.

[21]  C. Mueller,et al.  Control of mitochondrial biogenesis during myogenesis. , 2006, American journal of physiology. Cell physiology.

[22]  Keisuke Ito,et al.  Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells , 2006, Nature Medicine.

[23]  E. Levin,et al.  Estrogen Prevents Cardiomyocyte Apoptosis through Inhibition of Reactive Oxygen Species and Differential Regulation of p38 Kinase Isoforms* , 2006, Journal of Biological Chemistry.

[24]  Jiahuai Han,et al.  TAB-1 Modulates Intracellular Localization of p38 MAP Kinase and Downstream Signaling* , 2006, Journal of Biological Chemistry.

[25]  S. Schreiber,et al.  Oral p38 mitogen-activated protein kinase inhibition with BIRB 796 for active Crohn's disease: a randomized, double-blind, placebo-controlled trial. , 2006, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[26]  H. J. Kim,et al.  Osteoclast differentiation requires TAK1 and MKK6 for NFATc1 induction and NF-κB transactivation by RANKL , 2006, Cell Death and Differentiation.

[27]  M. Nishita,et al.  MAPKAPK‐2‐mediated LIM‐kinase activation is critical for VEGF‐induced actin remodeling and cell migration , 2006, The EMBO journal.

[28]  Y. Le Marchand-Brustel,et al.  Inhibition of p38MAPK increases adipogenesis from embryonic to adult stages. , 2006, Diabetes.

[29]  J. Gogusev,et al.  Protein tyrosine kinase and p38 MAP kinase pathways are involved in stimulation of matrix metalloproteinase-9 by TNF-alpha in human monocytes. , 2006, Immunology letters.

[30]  P. Muñoz-Cánoves,et al.  Regulation of skeletal muscle gene expression by p38 MAP kinases. , 2006, Trends in cell biology.

[31]  Paola Briata,et al.  p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts. , 2005, Molecular cell.

[32]  G. Kollias,et al.  Generation and Characterization of p38β (MAPK11) Gene-Targeted Mice , 2005, Molecular and Cellular Biology.

[33]  J. Molkentin,et al.  Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion. , 2005, American journal of physiology. Heart and circulatory physiology.

[34]  H. Otani,et al.  Role of F-actin organization in p38 MAP kinase-mediated apoptosis and necrosis in neonatal rat cardiomyocytes subjected to simulated ischemia and reoxygenation. , 2005, American journal of physiology. Heart and circulatory physiology.

[35]  Matthew R. Lee,et al.  MAP Kinase p38Inhibitors: Clinical Results and an Intimate Look at Their Interactions with p38α Protein , 2005 .

[36]  J. Ninomiya-Tsuji,et al.  AMP-Activated Protein Kinase Activates p38 Mitogen-Activated Protein Kinase by Increasing Recruitment of p38 MAPK to TAB1 in the Ischemic Heart , 2005, Circulation research.

[37]  M. Pickering,et al.  Actions of TNF‐α on glutamatergic synaptic transmission in the central nervous system , 2005 .

[38]  R. Polosa,et al.  TNF-α as a promising therapeutic target in chronic asthma: a lesson from rheumatoid arthritis , 2005 .

[39]  Rodolfo Marquez,et al.  The Mnks are novel components in the control of TNF alpha biosynthesis and phosphorylate and regulate hnRNP A1. , 2005, Immunity.

[40]  A. Fanning.  Faculty Opinions recommendation of p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP. , 2005 .

[41]  P. Cohen,et al.  The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ. , 2005, The Biochemical journal.

[42]  John J. Andreucci,et al.  Regulation of vertebrate myotome development by the p38 MAP kinase-MEF2 signaling pathway. , 2005, Developmental biology.

[43]  D. Jeoung,et al.  Tetraspanin CD9 induces MMP-2 expression by activating p38 MAPK, JNK and c-Jun pathways in human melanoma cells , 2005, Experimental & Molecular Medicine.

[44]  S. Takai,et al.  alphaB-crystallin is phosphorylated during myocardial infarction: involvement of platelet-derived growth factor-BB. , 2005, Archives of biochemistry and biophysics.

[45]  A. Fornace,et al.  Cytokine-driven cell cycling is mediated through Cdc25A , 2005, The Journal of cell biology.

[46]  Xu Feng.  RANKing Intracellular Signaling in Osteoclasts , 2005, IUBMB life.

[47]  J. Garcia,et al.  The role of caldesmon in the regulation of endothelial cytoskeleton and migration , 2005, Journal of cellular physiology.

[48]  H. Otani,et al.  Temporary blockade of contractility during reperfusion elicits a cardioprotective effect of the p38 MAP kinase inhibitor SB-203580. , 2005, American journal of physiology. Heart and circulatory physiology.

[49]  Jenny Bain,et al.  BIRB796 Inhibits All p38 MAPK Isoforms in Vitro and in Vivo* , 2005, Journal of Biological Chemistry.

[50]  Yibin Wang,et al.  p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes. , 2005, Genes & development.

[51]  Xiaoke Huang,et al.  Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells. , 2005, Cancer research.

[52]  A. Moon,et al.  H-Ras-specific Activation of Rac-MKK3/6-p38 Pathway , 2005, Journal of Biological Chemistry.

[53]  N. Jones,et al.  The p38α/β MAPK functions as a molecular switch to activate the quiescent satellite cell , 2005, The Journal of cell biology.

[54]  R. Flavell,et al.  p38 MAPK Autophosphorylation Drives Macrophage IL-12 Production during Intracellular Infection1 , 2005, The Journal of Immunology.

[55]  E. Appella,et al.  Alternative p38 activation pathway mediated by T cell receptor–proximal tyrosine kinases , 2005, Nature Immunology.

[56]  Roger J. Davis,et al.  Role of the JIP4 Scaffold Protein in the Regulation of Mitogen-Activated Protein Kinase Signaling Pathways , 2005, Molecular and Cellular Biology.

[57]  M. Goedert,et al.  p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP , 2005, The EMBO journal.

[58]  H. Nishimatsu,et al.  Blockade of Endogenous Cytokines Mitigates Neointimal Formation in Obese Zucker Rats , 2005, Circulation.

[59]  E. Ballestar,et al.  E47 phosphorylation by p38 MAPK promotes MyoD/E47 association and muscle‐specific gene transcription , 2005, The EMBO journal.

[60]  Jennifer L. Doyle,et al.  MAPK signaling regulates endothelial cell assembly into networks and expression of MT1-MMP and MMP-2. , 2005, American journal of physiology. Cell physiology.

[61]  A. Fornace,et al.  The autoimmune suppressor Gadd45α inhibits the T cell alternative p38 activation pathway , 2005, Nature Immunology.

[62]  Bernhard Hirt,et al.  The p38 SAPK pathway is required for Ha-ras induced in vitro invasion of NIH3T3 cells. , 2005, Experimental cell research.

[63]  S. Sankey,et al.  Inhibition of p38 mitogen-activated protein kinase protects the heart against cardiac remodeling in mice with heart failure resulting from myocardial infarction. , 2005, Journal of cardiac failure.

[64]  Alan W. Stitt,et al.  Inhibition of tumor necrosis factor-alpha improves physiological angiogenesis and reduces pathological neovascularization in ischemic retinopathy. , 2005, The American journal of pathology.

[65]  M. Goedert,et al.  Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38δ at Thr50 promotes microtubule assembly , 2005, Journal of Cell Science.

[66]  M. Janakiraman,et al.  Stress kinase signaling in cancer: fact or fiction? , 2005, Cancer letters.

[67]  Michael B Yaffe,et al.  MAPKAP kinase-2 is a cell cycle checkpoint kinase that regulates the G2/M transition and S phase progression in response to UV irradiation. , 2005, Molecular cell.

[68]  R. Bolli,et al.  Overexpression of Mitogen-activated Protein Kinase Kinase 6 in the Heart Improves Functional Recovery from Ischemia in Vitro and Protects against Myocardial Infarction in Vivo* , 2005, Journal of Biological Chemistry.

[69]  R. Wersto,et al.  Intracellular acidosis‐activated p38 MAPK signaling and its essential role in cardiomyocyte hypoxic injury , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[70]  A. Mikhailov,et al.  The p38-Mediated Stress-Activated Checkpoint: A Rapid Response System for Delaying Progression through Antephase and Entry into Mitosis , 2005, Cell cycle.

[71]  N. Maulik,et al.  MK2-/- gene knockout mouse hearts carry anti-apoptotic signal and are resistant to ischemia reperfusion injury. , 2005, Journal of molecular and cellular cardiology.

[72]  R. Polosa,et al.  TNF-alpha as a promising therapeutic target in chronic asthma: a lesson from rheumatoid arthritis. , 2005, Clinical science.

[73]  Jiahuai Han,et al.  Essential role of p38gamma in K-Ras transformation independent of phosphorylation. , 2005, The Journal of biological chemistry.

[74]  M. Pickering,et al.  Actions of TNF-alpha on glutamatergic synaptic transmission in the central nervous system. , 2005, Experimental physiology.

[75]  Matthew R. Lee,et al.  MAP kinase p38 inhibitors: clinical results and an intimate look at their interactions with p38alpha protein. , 2005, Current medicinal chemistry.

[76]  F. Oesch,et al.  p38alpha MAPK is required for contact inhibition. , 2005, Oncogene.

[77]  F. Bost,et al.  The role of MAPKs in adipocyte differentiation and obesity. , 2005, Biochimie.

[78]  L. Platanias,et al.  Genistein Inhibits p 38 Map Kinase Activation , Matrix Metalloproteinase Type 2 , and Cell Invasion in Human Prostate Epithelial Cells , 2005 .

[79]  P. Moynagh,et al.  Dissection of tumor-necrosis factor-α inhibition of long-term potentiation (LTP) reveals a p38 mitogen-activated protein kinase-dependent mechanism which maps to early—but not late—phase LTP , 2004, Neuroscience.

[80]  J. Miyazaki,et al.  Mitogen-Activated Protein Kinase Plays a Critical Role in Cardiomyocyte Survival but Not in Cardiac Hypertrophic Growth in Response to Pressure Overload , 2004 .

[81]  P. Russell,et al.  The DNA damage response: sensing and signaling. , 2004, Current opinion in cell biology.

[82]  Jae-Hong Kim,et al.  Lipopolysaccharide Induces Matrix Metalloproteinase-9 Expression via a Mitochondrial Reactive Oxygen Species-p38 Kinase-Activator Protein-1 Pathway in Raw 264.7 Cells1 , 2004, The Journal of Immunology.

[83]  C. Peschel,et al.  Constitutive activation of the MAPkinase p38 is critical for MMP-9 production and survival of B-CLL cells on bone marrow stromal cells , 2004, Leukemia.

[84]  H. Krum,et al.  p38 mitogen-activated protein kinase inhibition improves cardiac function and attenuates left ventricular remodeling following myocardial infarction in the rat. , 2004, Journal of the American College of Cardiology.

[85]  A. Lindqvist,et al.  Characterisation of Cdc25B localisation and nuclear export during the cell cycle and in response to stress , 2004, Journal of Cell Science.

[86]  M. Jadot,et al.  Cholesterol depletion upregulates involucrin expression in epidermal keratinocytes through activation of p38. , 2004, The Journal of investigative dermatology.

[87]  A. Mikhailov,et al.  Topoisomerase II and histone deacetylase inhibitors delay the G2/M transition by triggering the p38 MAPK checkpoint pathway , 2004, The Journal of cell biology.

[88]  J. Pines,et al.  Chfr acts with the p38 stress kinases to block entry to mitosis in mammalian cells , 2004, The Journal of cell biology.

[89]  C. Simone,et al.  p38 pathway targets SWI-SNF chromatin-remodeling complex to muscle-specific loci , 2004, Nature Genetics.

[90]  J. Blenis,et al.  ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse Biological Functions , 2004, Microbiology and Molecular Biology Reviews.

[91]  M. Goedert,et al.  Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2. , 2004, The Biochemical journal.

[92]  S. Cook,et al.  ERK1/2 and p38 cooperate to induce a p21CIP1-dependent G1 cell cycle arrest , 2004, Oncogene.

[93]  D. Campbell,et al.  Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta. , 2004, The Biochemical journal.

[94]  J. Shabanowitz,et al.  MAPKAP Kinase 2 Phosphorylates Tristetraprolin on in Vivo Sites Including Ser178, a Site Required for 14-3-3 Binding* , 2004, Journal of Biological Chemistry.

[95]  L. Donehower,et al.  Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK–mediated activation of the p16Ink4a-p19Arf pathway , 2004, Nature Genetics.

[96]  K. Jacobson,et al.  Phosphorylation of paxillin by p38MAPK is involved in the neurite extension of PC-12 cells , 2004, The Journal of cell biology.

[97]  P. Muñoz-Cánoves,et al.  Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes , 2004, The EMBO journal.

[98]  M. Cotten,et al.  An efficient proteomics method to identify the cellular targets of protein kinase inhibitors , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[99]  D. Morrison,et al.  Regulation of MAP kinase signaling modules by scaffold proteins in mammals. , 2003, Annual review of cell and developmental biology.

[100]  M. Dell'Acqua,et al.  Rac–MEKK3–MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock , 2003, Nature Cell Biology.

[101]  A. Nebreda,et al.  Xp38γ/SAPK3 promotes meiotic G2/M transition in Xenopus oocytes and activates Cdc25C , 2003 .

[102]  P. Cohen,et al.  Feedback control of the protein kinase TAK1 by SAPK2a/p38α , 2003, The EMBO journal.

[103]  T. Yoshimura,et al.  Activation of Discoidin Domain Receptor 1 Facilitates the Maturation of Human Monocyte-Derived Dendritic Cells Through the TNF Receptor Associated Factor 6/TGF-β-Activated Protein Kinase 1 Binding Protein 1β/p38α Mitogen-Activated Protein Kinase Signaling Cascade , 2003, The Journal of Immunology.

[104]  R. Eckert,et al.  A Regulatory Role for p38δ MAPK in Keratinocyte Differentiation , 2003, Journal of Biological Chemistry.

[105]  Eun-Jung Lee,et al.  p38 kinase is a key signaling molecule for H-Ras-induced cell motility and invasive phenotype in human breast epithelial cells. , 2003, Cancer research.

[106]  Nobuyuki Tanaka,et al.  Mechanism of p38 MAP kinase activation in vivo. , 2003, Genes & development.

[107]  R. Flavell,et al.  Diverse Mechanisms of Myocardial p38 Mitogen-Activated Protein Kinase Activation: Evidence for MKK-Independent Activation by a TAB1-Associated Mechanism Contributing to Injury During Myocardial Ischemia , 2003, Circulation research.

[108]  J. Kremer,et al.  Potential of tumor necrosis factor neutralization strategies in rheumatologic disorders other than rheumatoid arthritis. , 2003, Seminars in arthritis and rheumatism.

[109]  T. Underhill,et al.  Inhibition of p38 MAPK signaling promotes late stages of myogenesis , 2003, Journal of Cell Science.

[110]  P. Pilch,et al.  ERK6 is expressed in a developmentally regulated manner in rodent skeletal muscle. , 2003, Biochemical and biophysical research communications.

[111]  Timothy E Hewett,et al.  Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling. , 2003, The Journal of clinical investigation.

[112]  Ricardo M Biondi,et al.  Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions. , 2003, The Biochemical journal.

[113]  R. Eckert,et al.  p38 Mitogen-Activated Protein Kinases on the Body Surface – A Function for p38δ , 2003 .

[114]  E. Nishida,et al.  Molecular recognitions in the MAP kinase cascades. , 2003, Cellular signalling.

[115]  S. Kostka,et al.  Affinity purification of ARE-binding proteins identifies polyA-binding protein 1 as a potential substrate in MK2-induced mRNA stabilization. , 2003, Biochemical and biophysical research communications.

[116]  M. Goedert,et al.  Repeat motifs of tau bind to the insides of microtubules in the absence of taxol , 2003, The EMBO journal.

[117]  R. Eckert,et al.  p38 Mitogen-activated protein kinases on the body surface--a function for p38 delta. , 2003, The Journal of investigative dermatology.

[118]  R. Eckert,et al.  A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation. , 2003, The Journal of biological chemistry.

[119]  M. Frödin,et al.  Xp38gamma/SAPK3 promotes meiotic G(2)/M transition in Xenopus oocytes and activates Cdc25C. , 2003, The EMBO journal.

[120]  C. Clevenger.  Signal transduction. , 2003, Breast disease.

[121]  M. Goldfarb,et al.  Fibroblast Growth Factor Homologous Factors and the Islet Brain-2 Scaffold Protein Regulate Activation of a Stress-activated Protein Kinase* , 2002, The Journal of Biological Chemistry.

[122]  Mary E. Choi,et al.  Requirement of Mitogen-activated Protein Kinase Kinase 3 (MKK3) for Activation of p38α and p38δ MAPK Isoforms by TGF-β1 in Murine Mesangial Cells* , 2002, The Journal of Biological Chemistry.

[123]  P. Cohen,et al.  Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP‐K2 and its interaction with cytokine mRNAs , 2002, The EMBO journal.

[124]  Jiahuai Han,et al.  Differentiation state-selective roles of p38 isoforms in human intestinal epithelial cell anoikis. , 2002, Gastroenterology.

[125]  Katharina Hanna,et al.  MCP-1 induces activation of MAP-kinases ERK, JNK and p38 MAPK in human endothelial cells , 2002 .

[126]  P. Cohen,et al.  Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways. , 2002, The Biochemical journal.

[127]  B. Heit,et al.  An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients , 2002, The Journal of cell biology.

[128]  T. Kuroki,et al.  Novel Protein Kinase C Isoforms Regulate Human Keratinocyte Differentiation by Activating a p38δ Mitogen-activated Protein Kinase Cascade That Targets CCAAT/Enhancer-binding Protein α* , 2002, The Journal of Biological Chemistry.

[129]  J. Landry,et al.  Activation of the p38 Signaling Pathway by Heat Shock Involves the Dissociation of Glutathione S-Transferase Mu from Ask1* , 2002, The Journal of Biological Chemistry.

[130]  Chen Dong,et al.  Differential involvement of p38 mitogen‐activated protein kinase kinases MKK3 and MKK6 in T‐cell apoptosis , 2002, EMBO reports.

[131]  Eulàlia de Nadal,et al.  Dealing with osmostress through MAP kinase activation , 2002, EMBO reports.

[132]  Reynold A Panettieri,et al.  PI3K is required for proliferation and migration of human pulmonary vascular smooth muscle cells. , 2002, American journal of physiology. Lung cellular and molecular physiology.

[133]  M. Gaestel,et al.  Distinct Cellular Functions of MK2 , 2002, Molecular and Cellular Biology.

[134]  D. Lambright,et al.  MAP Kinase Signaling Specificity , 2002, Science.

[135]  R. Buchsbaum,et al.  Interaction of Rac Exchange Factors Tiam1 and Ras-GRF1 with a Scaffold for the p38 Mitogen-Activated Protein Kinase Cascade , 2002, Molecular and Cellular Biology.

[136]  A. Verma,et al.  Cutting Edge: Activation of the p38 Mitogen-Activated Protein Kinase Signaling Pathway Mediates Cytokine-Induced Hemopoietic Suppression in Aplastic Anemia1 , 2002, The Journal of Immunology.

[137]  Radha Akella,et al.  Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b. , 2002, Molecular cell.

[138]  Albert J. Fornace,et al.  Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity , 2002, Nature Genetics.

[139]  L. Tong,et al.  Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site , 2002, Nature Structural Biology.

[140]  M. Goedert,et al.  Phosphorylation of microtubule‐associated protein tau by stress‐activated protein kinases in intact cells , 2002, FEBS letters.

[141]  Jiahuai Han,et al.  MAPKK-Independent Activation of p38α Mediated by TAB1-Dependent Autophosphorylation of p38α , 2002, Science.

[142]  G. Kollias,et al.  MK2 Targets AU-rich Elements and Regulates Biosynthesis of Tumor Necrosis Factor and Interleukin-6 Independently at Different Post-transcriptional Levels* , 2002, The Journal of Biological Chemistry.

[143]  J. Gutkind,et al.  Potent transforming activity of the small GTP‐binding protein Rit in NIH 3T3 cells: evidence for a role of a p38γ‐dependent signaling pathway , 2002, FEBS letters.

[144]  R. Eckert,et al.  Green Tea Polyphenol Stimulates a Ras, MEKK1, MEK3, and p38 Cascade to Increase Activator Protein 1 Factor-dependent Involucrin Gene Expression in Normal Human Keratinocytes* , 2002, The Journal of Biological Chemistry.

[145]  E. Kandel,et al.  Novel Mechanism for Gonadotropin-Releasing Hormone Neuronal Migration Involving Gas6/Ark Signaling to p38 Mitogen-Activated Protein Kinase , 2002, Molecular and Cellular Biology.

[146]  Jiahuai Han,et al.  MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha. , 2002, Science.

[147]  P. Plinkert,et al.  The p38 SAPK pathway regulates the expression of the MMP-9 collagenase via AP-1-dependent promoter activation. , 2001, Experimental cell research.

[148]  B. Ghetti,et al.  Activation of the JNK/p38 Pathway Occurs in Diseases Characterized by Tau Protein Pathology and Is Related to Tau Phosphorylation But Not to Apoptosis , 2001, Journal of neuropathology and experimental neurology.

[149]  A. Nebreda.  Faculty Opinions recommendation of A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta. , 2001 .

[150]  D. Kass,et al.  The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[151]  S Shimohama,et al.  Activation of MKK6, an upstream activator of p38, in Alzheimer's disease , 2001, Journal of neurochemistry.

[152]  R. Davis,et al.  Regulation of MAP kinases by docking domains , 2001, Biology of the cell.

[153]  C. Ambrosino,et al.  Cell cycle regulation by p38 MAP kinases , 2001, Biology of the cell.

[154]  T. Ishizuka,et al.  Sensitized Mast Cells Migrate Toward the Agen: A Response Regulated by p38 Mitogen-Activated Protein Kinase and Rho-Associated Coiled-Coil-Forming Protein Kinase1 , 2001, The Journal of Immunology.

[155]  Philip R. Cohen,et al.  A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38δ , 2001, The EMBO journal.

[156]  G. Sandusky,et al.  Decreased p38 MAPK activity in end-stage failing human myocardium: p38 MAPK alpha is the predominant isoform expressed in human heart. , 2001, Journal of molecular and cellular cardiology.

[157]  R. Eckert,et al.  MEK6 Regulates Human Involucrin Gene Expression via a p38α- and p38δ-dependent Mechanism , 2001, The Journal of Biological Chemistry.

[158]  M. Houde,et al.  Intestinal Epithelial Cell Differentiation Involves Activation of p38 Mitogen-activated Protein Kinase That Regulates the Homeobox Transcription Factor CDX2* , 2001, The Journal of Biological Chemistry.

[159]  M. Goedert.  The significance of tau and α-synuclein inclusions in neurodegenerative diseases , 2001 .

[160]  A. Lin,et al.  Activation of NF-κB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[161]  M. Goldfarb,et al.  Fibroblast growth factor homologous factors are intracellular signaling proteins , 2001, Current Biology.

[162]  E. Appella,et al.  Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase , 2001, Nature.

[163]  J. Avruch,et al.  Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. , 2001, Physiological reviews.

[164]  S. Santoro,et al.  α2 Integrin Subunit Cytoplasmic Domain-dependent Cellular Migration Requires p38 MAPK* , 2001, The Journal of Biological Chemistry.

[165]  G. Panayi,et al.  Cytokine pathways and joint inflammation in rheumatoid arthritis. , 2001, The New England journal of medicine.

[166]  J. Gutkind,et al.  Regulation of gene expression by the small GTPase Rho through the ERK6 (p38γ) MAP kinase pathway , 2001 .

[167]  A. Harken,et al.  Inhibition of caspase 1 reduces human myocardial ischemic dysfunction via inhibition of IL-18 and IL-1β , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[168]  S. Goldstone,et al.  Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR , 2001, Oncogene.

[169]  J. Trojanowski,et al.  Neurodegenerative tauopathies. , 2001, Annual review of neuroscience.

[170]  R. Eckert,et al.  MEK6 regulates human involucrin gene expression via a p38alpha - and p38delta -dependent mechanism. , 2001, The Journal of biological chemistry.

[171]  M. Goedert.  The significance of tau and alpha-synuclein inclusions in neurodegenerative diseases. , 2001, Current opinion in genetics & development.

[172]  J. Gutkind,et al.  Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway. , 2001, Genes & development.

[173]  I. Ferrer,et al.  Active, phosphorylation-dependent mitogen-activated protein kinase (MAPK/ERK), stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK), and p38 kinase expression in Parkinson's disease and Dementia with Lewy bodies , 2001, Journal of Neural Transmission.

[174]  C. Ambrosino,et al.  Differential Activation of p38 Mitogen-activated Protein Kinase Isoforms Depending on Signal Strength* , 2000, The Journal of Biological Chemistry.

[175]  Jiahuai Han,et al.  Myogenic differentiation requires signalling through both phosphatidylinositol 3-kinase and p38 MAP kinase. , 2000, Cellular signalling.

[176]  Masaaki Adachi,et al.  p53‐inducible Wip1 phosphatase mediates a negative feedback regulation of p38 MAPK‐p53 signaling in response to UV radiation , 2000, The EMBO journal.

[177]  J. Mudgett,et al.  Essential role for p38alpha mitogen-activated protein kinase in placental angiogenesis. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[178]  J. Pouysségur,et al.  Stress-activated Protein Kinases (JNK and p38/HOG) Are Essential for Vascular Endothelial Growth Factor mRNA Stability* , 2000, The Journal of Biological Chemistry.

[179]  H. Hoover,et al.  αB-crystallin Gene Induction and Phosphorylation by MKK6-activated p38 , 2000, The Journal of Biological Chemistry.

[180]  M. Karin,et al.  Requirement for p38α in Erythropoietin Expression A Role for Stress Kinases in Erythropoiesis , 2000, Cell.

[181]  R. Klein,et al.  Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development. , 2000, Molecular cell.

[182]  Zhenguo Wu,et al.  p38 and Extracellular Signal-Regulated Kinases Regulate the Myogenic Program at Multiple Steps , 2000, Molecular and Cellular Biology.

[183]  Y. Taya,et al.  A Role for the p38 Mitogen-activated Protein Kinase Pathway in the Transcriptional Activation of p53 on Genotoxic Stress by Chemotherapeutic Agents , 2000 .

[184]  Jacques Landry,et al.  Vascular Endothelial Growth Factor (VEGF)-driven Actin-based Motility Is Mediated by VEGFR2 and Requires Concerted Activation of Stress-activated Protein Kinase 2 (SAPK2/p38) and Geldanamycin-sensitive Phosphorylation of Focal Adhesion Kinase* , 2000, The Journal of Biological Chemistry.

[185]  S. Keyse,et al.  Protein phosphatases and the regulation of mitogen-activated protein kinase signalling. , 2000, Current opinion in cell biology.

[186]  H. Enslen,et al.  Molecular determinants that mediate selective activation of p38 MAP kinase isoforms , 2000, The EMBO journal.

[187]  Jiahuai Han,et al.  Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells. , 2000, Genes & development.

[188]  G. Johnson,et al.  Modulation of tau phosphorylation and intracellular localization by cellular stress. , 2000, The Biochemical journal.

[189]  D. Hanahan,et al.  The Hallmarks of Cancer , 2000, Cell.

[190]  H. Sheng,et al.  Posttranscriptional regulation of cyclooxygenase-2 in rat intestinal epithelial cells. , 2000, Neoplasia.

[191]  H. Hoover,et al.  alpha B-crystallin gene induction and phosphorylation by MKK6-activated p38. A potential role for alpha B-crystallin as a target of the p38 branch of the cardiac stress response. , 2000, The Journal of biological chemistry.

[192]  P. Cohen,et al.  Specificity and mechanism of action of some commonly used protein kinase inhibitors. , 2000, The Biochemical journal.

[193]  D. Bulavin,et al.  Deregulation of p53/p21Cip1/Waf1 pathway contributes to polyploidy and apoptosis of E1A+cHa-ras transformed cells after γ-irradiation , 1999, Oncogene.

[194]  K. Wilson,et al.  The structure of phosphorylated p38gamma is monomeric and reveals a conserved activation-loop conformation. , 1999, Structure.

[195]  J. Hedges,et al.  A Role for p38MAPK/HSP27 Pathway in Smooth Muscle Cell Migration* , 1999, The Journal of Biological Chemistry.

[196]  S. Cook,et al.  Activation of c-Jun N-terminal kinases and p38-mitogen-activated protein kinases in human heart failure secondary to ischaemic heart disease. , 1999, Journal of molecular and cellular cardiology.

[197]  P. Cohen,et al.  Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages. , 1999, Cellular signalling.

[198]  Jeffrey L. Wrana,et al.  Post-translational control of the MEF2A transcriptional regulatory protein , 1999, Nucleic Acids Res..

[199]  R. Heuertz,et al.  C-reactive Protein Inhibits Chemotactic Peptide-induced p38 Mitogen-activated Protein Kinase Activity and Human Neutrophil Movement* , 1999, The Journal of Biological Chemistry.

[200]  J. Gutkind,et al.  A Network of Mitogen-Activated Protein Kinases Links G Protein-Coupled Receptors to the c-jun Promoter: a Role for c-Jun NH2-Terminal Kinase, p38s, and Extracellular Signal-Regulated Kinase 5 , 1999, Molecular and Cellular Biology.

[201]  M. Gaestel,et al.  MAPKAP kinase 2 is essential for LPS-induced TNF-α biosynthesis , 1999, Nature Cell Biology.

[202]  P. Cohen,et al.  Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition. , 1999, The Journal of biological chemistry.

[203]  I. Mellman,et al.  Defective IL‐12 production in mitogen‐activated protein (MAP) kinase kinase 3 (Mkk3)‐deficient mice , 1999, The EMBO journal.

[204]  R. Flavell,et al.  Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[205]  J. Ninomiya-Tsuji,et al.  The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway , 1999, Nature.

[206]  G. Kollias,et al.  Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies. , 1999, Immunity.

[207]  E. Bengal,et al.  p38 Mitogen-activated Protein Kinase Pathway Promotes Skeletal Muscle Differentiation , 1999, The Journal of Biological Chemistry.

[208]  P. Cohen,et al.  Stress-activated Protein Kinase-2/p38 and a Rapamycin-sensitive Pathway Are Required for C2C12 Myogenesis* , 1999, The Journal of Biological Chemistry.

[209]  Jiahuai Han,et al.  Regulation of the MEF2 Family of Transcription Factors by p38 , 1999, Molecular and Cellular Biology.

[210]  J. Hedges,et al.  A role for p38(MAPK)/HSP27 pathway in smooth muscle cell migration. , 1999, The Journal of biological chemistry.

[211]  M. Gaestel,et al.  MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis. , 1999, Nature cell biology.

[212]  M. Gaestel,et al.  Kotlyarov, A. et al. MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis. Nat. Cell Biol. 1, 94-97 , 1999 .

[213]  J. Dean,et al.  A p38 MAP kinase inhibitor regulates stability of interleukin‐1‐induced cyclooxygenase‐2 mRNA , 1998, FEBS letters.

[214]  E. Levin,et al.  Heat shock protein 27 kDa expression and phosphorylation regulates endothelial cell migration , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[215]  C. Marshall,et al.  Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2 , 1998, Current Biology.

[216]  J. Yasuda,et al.  A mammalian scaffold complex that selectively mediates MAP kinase activation. , 1998, Science.

[217]  T. Kohno,et al.  Identification of stathmin as a novel substrate for p38 delta. , 1998, Biochemical and biophysical research communications.

[218]  Mutsuhiro Takekawa,et al.  Protein phosphatase 2Cα inhibits the human stress‐responsive p38 and JNK MAPK pathways , 1998, The EMBO journal.

[219]  Elizabeth J. Goldsmith,et al.  Acquisition of Sensitivity of Stress-activated Protein Kinases to the p38 Inhibitor, SB 203580, by Alteration of One or More Amino Acids within the ATP Binding Pocket* , 1998, The Journal of Biological Chemistry.

[220]  P. Cohen,et al.  Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution. , 1998, Chemistry & biology.

[221]  D. Boyd,et al.  Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion. , 1998, Cancer research.

[222]  Jiahuai Han,et al.  Cardiac Hypertrophy Induced by Mitogen-activated Protein Kinase Kinase 7, a Specific Activator for c-Jun NH2-terminal Kinase in Ventricular Muscle Cells* , 1998, The Journal of Biological Chemistry.

[223]  Roger J. Davis,et al.  Selective Activation of p38 Mitogen-activated Protein (MAP) Kinase Isoforms by the MAP Kinase Kinases MKK3 and MKK6* , 1998, The Journal of Biological Chemistry.

[224]  B. Black,et al.  Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. , 1998, Annual review of cell and developmental biology.

[225]  J. Massagué.  TGF-beta signal transduction. , 1998, Annual review of biochemistry.

[226]  Jiahuai Han,et al.  Regulation of the MEF 2 Family of Transcription Factors by p 38 † , 1998 .

[227]  Yong Jiang,et al.  Characterization of the Structure and Function of the Fourth Member of p38 Group Mitogen-activated Protein Kinases, p38δ* , 1997, The Journal of Biological Chemistry.

[228]  D. Zechner,et al.  A Role for the p38 Mitogen-activated Protein Kinase Pathway in Myocardial Cell Growth, Sarcomeric Organization, and Cardiac-specific Gene Expression , 1997, The Journal of cell biology.

[229]  Jacques Landry,et al.  p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells , 1997, Oncogene.

[230]  Elizabeth J. Goldsmith,et al.  Activation Mechanism of the MAP Kinase ERK2 by Dual Phosphorylation , 1997, Cell.

[231]  P. Cohen,et al.  The search for physiological substrates of MAP and SAP kinases in mammalian cells. , 1997, Trends in cell biology.

[232]  J. Downey,et al.  Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart. , 1997, Journal of molecular and cellular cardiology.

[233]  G. Yu,et al.  Expression of mitogen-inducible cyclooxygenase induced by lipopolysaccharide: mediation through both mitogen-activated protein kinase and NF-kappaB signaling pathways in macrophages. , 1997, Biochemical pharmacology.

[234]  J C Lee,et al.  Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles. , 1997, Biochemical and biophysical research communications.

[235]  Philip R. Cohen,et al.  Activation of the novel stress‐activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases , 1997, The EMBO journal.

[236]  Philip R. Cohen,et al.  Phosphorylation of microtubule‐associated protein tau by stress‐activated protein kinases , 1997, FEBS letters.

[237]  G. MacGowan,et al.  Circulating interleukin-6 in severe heart failure. , 1997, The American journal of cardiology.

[238]  Jiahuai Han,et al.  Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation , 1997, Nature.

[239]  J. Landry,et al.  Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells. , 1997, Circulation research.

[240]  J. Landry,et al.  Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27. , 1997, Journal of cell science.

[241]  Philip R. Cohen,et al.  Activation of stress‐activated protein kinase‐3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38) , 1997, The EMBO journal.

[242]  Minoru Takagi,et al.  Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways , 1997, Science.

[243]  D. Zechner,et al.  A Role for the p 38 Mitogen-activated Protein Kinase Pathway in Myocardial Cell Growth , Sarcomeric Organization , and Cardiac-specific Gene Expression , 1997 .

[244]  M. Karin,et al.  Three distinct signalling responses by murine fibroblasts to genotoxic stress , 1996, Nature.

[245]  L. Bardwell,et al.  A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs. , 1996, Trends in biochemical sciences.

[246]  P. Cohen,et al.  Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress‐ and cytokine‐stimulated monocytes and epithelial cells. , 1996, The EMBO journal.

[247]  A. Ashworth,et al.  Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion. , 1996, Circulation research.

[248]  A. Ullrich,et al.  ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[249]  W. Fiers,et al.  The p38/RK mitogen‐activated protein kinase pathway regulates interleukin‐6 synthesis response to tumor necrosis factor. , 1996, The EMBO journal.

[250]  M. Goedert,et al.  SAP kinase‐3, a new member of the family of mammalian stress‐activated protein kinases , 1996, FEBS letters.

[251]  R. Davis,et al.  MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway , 1996, Molecular and cellular biology.

[252]  K. Irie,et al.  Identification of a Member of the MAPKKK Family as a Potential Mediator of TGF-β Signal Transduction , 1995, Science.

[253]  L. Shapiro,et al.  Osmotic regulation of cytokine synthesis in vitro. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[254]  Jiahuai Han,et al.  Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1 (*) , 1995, The Journal of Biological Chemistry.

[255]  Philip R. Cohen,et al.  SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1 , 1995, FEBS letters.

[256]  Jiahuai Han,et al.  Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine (*) , 1995, The Journal of Biological Chemistry.

[257]  Jiahuai Han,et al.  Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms , 1995, Science.

[258]  J. Landry,et al.  Modulation of cellular thermoresistance and actin filament stability accompanies phosphorylation-induced changes in the oligomeric structure of heat shock protein 27 , 1995, Molecular and cellular biology.

[259]  Jerry L. Adams,et al.  A protein kinase involved in the regulation of inflammatory cytokine biosynthesis , 1994, Nature.

[260]  Michel Morange,et al.  A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins , 1994, Cell.

[261]  J. Hsuan,et al.  Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of hsp27 , 1994, Cell.

[262]  J. Behlke,et al.  Phosphorylation and supramolecular organization of murine small heat shock protein HSP25 abolish its actin polymerization-inhibiting activity. , 1994, The Journal of biological chemistry.

[263]  L Bibbs,et al.  A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. , 1994, Science.

[264]  A. Newby,et al.  Extracellular matrix degrading metalloproteinases in the pathogenesis of arteriosclerosis. , 1994, Basic research in cardiology.

[265]  Y. Ihara,et al.  τ in Paired Helical Filaments Is Functionally Distinct from Fetal τ: Assembly Incompetence of Paired Helical Filament‐τ , 1993 .

[266]  John Q. Trojanowski,et al.  Abnormal tau phosphorylation at Ser396 in alzheimer's disease recapitulates development and contributes to reduced microtubule binding , 1993, Neuron.

[267]  E. Winter,et al.  An osmosensing signal transduction pathway in yeast. , 1993, Science.

[268]  Y. Ihara,et al.  Tau in paired helical filaments is functionally distinct from fetal tau: assembly incompetence of paired helical filament-tau. , 1993, Journal of neurochemistry.

[269]  David Stokoe,et al.  Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins , 1992, FEBS letters.

[270]  B. Geiger,et al.  A 25-kD inhibitor of actin polymerization is a low molecular mass heat shock protein , 1991, The Journal of cell biology.