MUC4 (mucin 4, cell surface associated)

Review on MUC4 (mucin 4, cell surface associated), with data on DNA, on the protein encoded, and where the gene is implicated.

[1]  S. Batra,et al.  MUC4 (mucin 4, cell surface associated) , 2011 .

[2]  M. Copin,et al.  Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1alpha. , 2007, The Biochemical journal.

[3]  S. Batra,et al.  Emerging roles of MUC4 in cancer: a novel target for diagnosis and therapy. , 2007, Cancer research.

[4]  M. Copin,et al.  MUC4 expression is regulated by cystic fibrosis transmembrane conductance regulator in pancreatic adenocarcinoma cells via transcriptional and post-translational mechanisms , 2007, Oncogene.

[5]  Lynette M. Smith,et al.  Aberrant expression of MUC4 in ovarian carcinoma: diagnostic significance alone and in combination with MUC1 and MUC16 (CA125) , 2006, Modern Pathology.

[6]  S. Batra,et al.  MUC4-Expressing Pancreatic Adenocarcinomas Show Elevated Levels of Both TH1 and TH2 Cytokines: Potential Pathobiologic Implications , 2006, The American Journal of Gastroenterology.

[7]  C. A. Carraway,et al.  Membrane Mucin Muc4 Induces Density-dependent Changes in ERK Activation in Mammary Epithelial and Tumor Cells , 2006, Journal of Biological Chemistry.

[8]  Cary Lai,et al.  The Mucin Muc4 Potentiates Neuregulin Signaling by Increasing the Cell-surface Populations of ErbB2 and ErbB3* , 2006, Journal of Biological Chemistry.

[9]  A. Farooq,et al.  Muc4-ErbB2 complex formation and signaling in polarized CACO-2 epithelial cells indicate that Muc4 acts as an unorthodox ligand for ErbB2. , 2006, Molecular biology of the cell.

[10]  B. Xia,et al.  IL-9 Modulated MUC4 Gene and Glycoprotein Expression in Airway Epithelial Cells , 2006, Bioscience reports.

[11]  B. Xia,et al.  IL-4 induced MUC4 enhancement in respiratory epithelial cells in vitro is mediated through JAK-3 selective signaling , 2006, Respiratory research.

[12]  Sangeeta Bafna,et al.  Aberrant expression of transmembrane mucins, MUC1 and MUC4, in human prostate carcinomas , 2006, The Prostate.

[13]  J. Meza,et al.  Synergistic induction of the MUC4 mucin gene by interferon-γ and retinoic acid in human pancreatic tumour cells involves a reprogramming of signalling pathways , 2005, Oncogene.

[14]  P. Siersema,et al.  MUC4 is increased in high grade intraepithelial neoplasia in Barrett’s oesophagus and is associated with a proapoptotic Bax to Bcl-2 ratio , 2004, Journal of Clinical Pathology.

[15]  S. Batra,et al.  Multiple roles of mucins in pancreatic cancer, a lethal and challenging malignancy , 2004, British Journal of Cancer.

[16]  S. Batra,et al.  A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-β in pancreatic carcinogenesis , 2004, Oncogene.

[17]  S. Batra,et al.  MUC4 mucin expression in human pancreatic tumours is affected by organ environment: the possible role of TGFβ2 , 2004, British Journal of Cancer.

[18]  S. Batra,et al.  Generation and Characterization of Anti-MUC4 Monoclonal Antibodies Reactive with Normal and Cancer Cells in Humans , 2004, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[19]  S. Batra,et al.  Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway. , 2004, The Biochemical journal.

[20]  Michael A. Hollingsworth,et al.  Mucins in cancer: protection and control of the cell surface , 2004, Nature Reviews Cancer.

[21]  C. A. Carraway,et al.  Muc4/Sialomucin Complex, the Intramembrane ErbB2 Ligand, Translocates ErbB2 to the Apical Surface in Polarized Epithelial Cells* , 2003, Journal of Biological Chemistry.

[22]  S. Batra,et al.  Aberrant Expression of MUC3 and MUC4 Membrane-Associated Mucins and Sialyl Lex Antigen in Pancreatic Intraepithelial Neoplasia , 2003, Pancreas.

[23]  S. Batra,et al.  Genomic organization of MUC4 mucin gene. Towards the characterization of splice variants. , 2002, European journal of biochemistry.

[24]  J. Cameron,et al.  MUC4 expression increases progressively in pancreatic intraepithelial neoplasia. , 2002, American journal of clinical pathology.

[25]  C. A. Carraway,et al.  Muc4/sialomucin complex, the intramembrane ErbB2 ligand, in cancer and epithelia: to protect and to survive. , 2002, Progress in nucleic acid research and molecular biology.

[26]  H. Friess,et al.  Mucin (MUC) gene expression in human pancreatic adenocarcinoma and chronic pancreatitis: a potential role of MUC4 as a tumor marker of diagnostic significance. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[27]  A. Choudhury,et al.  Alternate splicing at the 3'-end of the human pancreatic tumor-associated mucin MUC4 cDNA. , 2001, Teratogenesis, carcinogenesis, and mutagenesis.

[28]  M. Copin,et al.  Developmental Mucin Gene Expression in the Gastroduodenal Tract and Accessory Digestive Glands. II. Duodenum and Liver, Gallbladder, and Pancreas , 2000, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[29]  M. Copin,et al.  Developmental Mucin Gene Expression in the Gastroduodenal Tract and Accessory Digestive Glands. I. Stomach: A Relationship to Gastric Carcinoma , 2000, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[30]  S. Batra,et al.  Retinoic Acid-dependent Transforming Growth Factor-β2-mediated Induction of MUC4 Mucin Expression in Human Pancreatic Tumor Cells Follows Retinoic Acid Receptor-α Signaling Pathway* , 2000, The Journal of Biological Chemistry.

[31]  F. Escande,et al.  Alternative splicing generates a family of putative secreted and membrane-associated MUC4 mucins. , 2000, European journal of biochemistry.

[32]  N. Moniaux,et al.  Complete sequence of the human mucin MUC4: a putative cell membrane-associated mucin. , 1999, The Biochemical journal.

[33]  M. Copin,et al.  Developmental mucin gene expression in the human respiratory tract. , 1999, American journal of respiratory cell and molecular biology.

[34]  I. Gipson,et al.  MUC4 and MUC5B transcripts are the prevalent mucin messenger ribonucleic acids of the human endocervix. , 1999, Biology of reproduction.

[35]  T. Savidge,et al.  Mucin gene expression in human embryonic and fetal intestine , 1998, Gut.

[36]  N. Moniaux,et al.  Human mucin gene MUC4: organization of its 5'-region and polymorphism of its central tandem repeat array. , 1998, The Biochemical journal.

[37]  M. Gross,et al.  Mucin 4 (MUC4) gene: regional assignment (3q29) and RFLP analysis. , 1992, Annales de genetique.