Online measurement and evaluation of the Er:YAG laser ablation process using an integrated OCT system

Laser surgery has gained clinical importance due to numerous advantages including contact-free processing, arbitrary cutting geometries, and high precision. However, online process control remains a challenge for widespread clinical use. Therefore, we established a combined setup of a pulsed Er:YAG laser ( = 2940 nm) and an optical coherence tomography (OCT) ( = 930 nm) for in situ monitoring of hard tissue ablation. The optical setup facilitates an interactive control of the laser ablation depth and remaining tissue strength through the depth resolution of OCT. The 3D OCT data-set, which is acquired after ablation, provides contours and layer thicknesses.

[1]  M W Berns,et al.  Mid‐infrared erbium:YAG laser ablation of bone: The effect of laser osteotomy on bone healing , 1989, Lasers in surgery and medicine.

[2]  B. H. Park,et al.  Signal Processing Overview of Optical Coherence Tomography Systems for Medical Imaging , 2010 .

[3]  Gaspare Palaia,et al.  Bone damage induced by different cutting instruments--an in vitro study. , 2009, Brazilian dental journal.

[4]  Tim Lüth,et al.  A New Approach for Creating Defined Geometries by Navigated Laser Ablation Based on Volumetric 3-D Data , 2008, IEEE Transactions on Biomedical Engineering.

[5]  T J Flotte,et al.  Er:YAG laser ablation of tissue: Effect of pulse duration and tissue type on thermal damage , 1989, Lasers in surgery and medicine.

[6]  S A Boppart,et al.  High-resolution optical coherence tomography-guided laser ablation of surgical tissue. , 1999, The Journal of surgical research.

[7]  Bodo Rosenhahn,et al.  Model Based 3D Segmentation and OCT Image Undistortion of Percutaneous Implants , 2011, MICCAI.

[8]  Demetri Terzopoulos,et al.  Snakes: Active contour models , 2004, International Journal of Computer Vision.

[9]  J. Fujimoto,et al.  Optical coherence tomography: technology and applications , 2002, IEEE/LEOS International Conference on Optical MEMs.

[10]  Jerry L. Prince,et al.  Generalized gradient vector flow external forces for active contours , 1998, Signal Process..

[11]  A. Ascenzi,et al.  Technique for Dissection and Measurement of Refractive Index of Osteones , 1959, The Journal of biophysical and biochemical cytology.

[12]  Delia Cabrera Fernandez,et al.  Delineating fluid-filled region boundaries in optical coherence tomography images of the retina , 2005, IEEE Transactions on Medical Imaging.

[13]  A. Vogel,et al.  Mechanisms of pulsed laser ablation of biological tissues. , 2003, Chemical reviews.

[14]  Jitendra Malik,et al.  Scale-Space and Edge Detection Using Anisotropic Diffusion , 1990, IEEE Trans. Pattern Anal. Mach. Intell..

[15]  M. Niemz Laser-Tissue Interactions , 1996 .

[16]  Masato Ohmi,et al.  Real-time OCT imaging of laser ablation of biological tissue , 2010, BiOS.