Comparison of antibacterial activities of cadmium oxide nanoparticles against Pseudomonas Aeruginosa and Staphylococcus Aureus bacteria

Background: Inorganic antibacterial factors have bacterial resistance and high thermal stability. Inorganic nanomaterials which have new structures with biological, chemical and physical properties have been made since their applications due to their nano size. In this study, the antibacterial effect of cadmium oxide nanoparticles on Staphylococcus aureus and Pseudomonas aeruginosa bacteria was investigated. Materials and Methods: The different concentrations (10 μg/ml, 15 μg/ml and 20 μg/ml) of cadmium oxide nanoparticles were prepared and their effects were studied against considered bacteria in both solid and liquid media. Results: The results showed that there is a direct relationship between inhibitory effect and amount of consumer dose of nanoparticles. Furthermore, it was observed that antibacterial properties of cadmium oxide nanoparticles on activity and growth of Staphylococcus aureus was more effective than Pseudomonas aeruginosa. Conclusion: This study showed that antibacterial effects of cadmium oxide nanoparticles on positive gram bacteria are stronger than negative gram bacteria and antibacterial effects of cdo nanoparticles against both bacteria, but Staphylococcus aureus bacteria were more sensitive to nanoparticles as compared to Pseudomonas aeruginosa.

[1]  M. Shahedi,et al.  Effect of nanocomposite packaging containing Ag and ZnO on inactivation of Lactobacillus plantarum in orange juice , 2011 .

[2]  Ali Moballegh,et al.  ZnO nanoparticles enhanced antibacterial activity of ciprofloxacin against Staphylococcus aureus and Escherichia coli. , 2010, Journal of biomedical materials research. Part B, Applied biomaterials.

[3]  Juan Francisco Hernández-Sierra,et al.  The antimicrobial sensitivity of Streptococcus mutans to nanoparticles of silver, zinc oxide, and gold. , 2008, Nanomedicine : nanotechnology, biology, and medicine.

[4]  Siddhartha P Duttagupta,et al.  Strain specificity in antimicrobial activity of silver and copper nanoparticles. , 2008, Acta biomaterialia.

[5]  M. Yacamán,et al.  The bactericidal effect of silver nanoparticles , 2005, Nanotechnology.

[6]  K. Klabunde,et al.  Metal Oxide Nanoparticles as Bactericidal Agents , 2002 .

[7]  Neva Ciftcioglu,et al.  Nanobacteria: An alternative mechanism for pathogenic intra- and extracellular calcification and stone formation , 1998 .

[8]  Alexander T. Florence,et al.  Enhanced Oral Uptake of Tomato Lectin-Conjugated Nanoparticles in the Rat , 1997, Pharmaceutical Research.

[9]  O. Kafri,et al.  Mycobacteria possess a surprisingly small number of ribosomal RNA genes in relation to the size of their genome. , 1986, Biochemical and biophysical research communications.

[10]  M. Rai,et al.  Silver nanoparticles as a new generation of antimicrobials. , 2009, Biotechnology advances.