An Automatic System for Real-Time Identifying Atrial Fibrillation by Using a Lightweight Convolutional Neural Network

A lightweight convolutional neural network (CNN) is presented in this study to automatically indentify atrial fibrillation (AF) from single-lead ECG recording. In contrast to existing methods employing a deeper architecture or complex feature-engineered inputs, this work presents an attempt to employ a lightweight CNN to confront current drawbacks such as higher computational requirement and inadequate training dataset, by using representative rhythms features of AF rather than raw ECG signal or hand-crafted features without any electrophysiological considerations. The experimental results suggested that this method presents the following significant advantages: (1) higher performances for indentifying AF in terms of accuracy, sensitivity, and specificity that are 97.5%, 97.8%, and 97.2%, respectively; (2) It is capable of automatically extracting the shared features of AF episodes of different patients and would be much robust and reliable; (3) with the cardiac rhythm features as input dataset, rather than complex transforming and classifying the raw data, thus requiring a lower computational resource. In conclusion, this automated method could analyze large amounts of data in a short time while assuring a relative high accuracy, and thus would potentially serve to provide a comfortable single-lead monitoring for patients and a clinical useful tool for doctors.

[1]  D. Finlay,et al.  Automated detection of atrial fibrillation using R-R intervals and multivariate-based classification. , 2016, Journal of Electrocardiology.

[2]  Masoumeh Haghpanahi,et al.  Cardiologist-level arrhythmia detection and classification in ambulatory electrocardiograms using a deep neural network , 2019, Nature Medicine.

[3]  Jie Lian,et al.  A simple method to detect atrial fibrillation using RR intervals. , 2011, The American journal of cardiology.

[4]  I. Romero,et al.  Comparative study of algorithms for Atrial Fibrillation detection , 2011, 2011 Computing in Cardiology.

[5]  Albert Hofman,et al.  Projections on the number of individuals with atrial fibrillation in the European Union, from 2000 to 2060. , 2013, European heart journal.

[6]  Shoushui Wei,et al.  Atrial Fibrillation Beat Identification Using the Combination of Modified Frequency Slice Wavelet Transform and Convolutional Neural Networks , 2018, Journal of healthcare engineering.

[7]  Junichiro Hayano,et al.  Exponential Distribution of Long Heart Beat Intervals During Atrial Fibrillation and Their Relevance for White Noise Behaviour in Power Spectrum , 2006, Journal of biological physics.

[8]  Ming Liu,et al.  Atrial Fibrillation Detection by the Combination of Recurrence Complex Network and Convolution Neural Network , 2019, Journal of Probability and Statistics.

[9]  Behnaz Ghoraani,et al.  Developing an atrial activity-based algorithm for detection of atrial fibrillation , 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[10]  Jichao Zhao,et al.  Robust ECG signal classification for detection of atrial fibrillation using a novel neural network , 2017, 2017 Computing in Cardiology (CinC).

[11]  Rishikesan Kamaleswaran,et al.  A robust deep convolutional neural network for the classification of abnormal cardiac rhythm using single lead electrocardiograms of variable length , 2018, Physiological measurement.

[12]  Adfal Afdala,et al.  RR-Interval variance of electrocardiogram for atrial fibrillation detection , 2016 .

[13]  U. Rajendra Acharya,et al.  Automated detection of arrhythmias using different intervals of tachycardia ECG segments with convolutional neural network , 2017, Inf. Sci..

[14]  Alireza Mehrnia,et al.  Automatic detection of atrial fibrillation using stationary wavelet transform and support vector machine , 2015, Comput. Biol. Medicine.

[15]  Roberto Sassi,et al.  An Extended Bayesian Framework for Atrial and Ventricular Activity Separation in Atrial Fibrillation , 2017, IEEE Journal of Biomedical and Health Informatics.

[16]  Guigang Zhang,et al.  Deep Learning , 2016, Int. J. Semantic Comput..

[17]  J. Steinberg,et al.  The signal-averaged P wave duration: a rapid and noninvasive marker of risk of atrial fibrillation. , 1993, Journal of the American College of Cardiology.

[18]  D. Levy,et al.  Impact of atrial fibrillation on the risk of death: the Framingham Heart Study. , 1998, Circulation.

[19]  Leif Sörnmo,et al.  Sequential characterization of atrial tachyarrhythmias based on ECG time-frequency analysis , 2004, IEEE Transactions on Biomedical Engineering.

[20]  Haitham M. Al-Angari,et al.  Atrial fibrillation and waveform characterization. A time domain perspective in the surface ECG. , 2006, IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society.

[21]  Hakan Oral,et al.  75 – Atrial Fibrillation: Paroxysmal, Persistent, and Permanent , 2013 .

[22]  C. Israel,et al.  Long-term risk of recurrent atrial fibrillation as documented by an implantable monitoring device: implications for optimal patient care. , 2004, Journal of the American College of Cardiology.

[23]  Sunil T. Mathew,et al.  Atrial fibrillation: mechanistic insights and treatment options. , 2009, European journal of internal medicine.

[24]  Sarabjeet Singh Mehta,et al.  Detection and delineation of P and T waves in 12-lead electrocardiograms , 2009, Expert Syst. J. Knowl. Eng..

[25]  D. Linker,et al.  Accurate, Automated Detection of Atrial Fibrillation in Ambulatory Recordings , 2016, Cardiovascular engineering and technology.

[26]  M. Chung,et al.  2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation , 2017, Heart rhythm.

[27]  D. Singer,et al.  Estimates of current and future incidence and prevalence of atrial fibrillation in the U.S. adult population. , 2013, The American journal of cardiology.

[28]  Yifei Zhang,et al.  Convolutional Neural Network Based Detection of Atrial Fibrillation Combing R-R intervals and F-wave Frequency Spectrum * , 2019, 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[29]  J. Mant,et al.  How can we best detect atrial fibrillation? , 2012, The journal of the Royal College of Physicians of Edinburgh.

[30]  Sheng Lu,et al.  Automatic Real Time Detection of Atrial Fibrillation , 2009, Annals of Biomedical Engineering.

[31]  Jeffrey M. Hausdorff,et al.  Physionet: Components of a New Research Resource for Complex Physiologic Signals". Circu-lation Vol , 2000 .

[32]  Boyoung Joung,et al.  Variations of Prevalence and Incidence of Atrial Fibrillation and Oral Anticoagulation Rate According to Different Analysis Approaches , 2018, Scientific Reports.

[33]  Haitham M. Al-Angari,et al.  Atrial fibrillation and waveform characterization , 2006, IEEE Engineering in Medicine and Biology Magazine.

[34]  Han Yuan,et al.  Automated Detection of High Frequency Oscillations in Intracranial EEG Using the Combination of Short-Time Energy and Convolutional Neural Networks , 2019, IEEE Access.

[35]  Henggui Zhang,et al.  Detecting atrial fibrillation by deep convolutional neural networks , 2018, Comput. Biol. Medicine.

[36]  Ki H. Chon,et al.  Atrial flutter and atrial tachycardia detection using Bayesian approach with high resolution time-frequency spectrum from ECG recordings , 2013, Biomed. Signal Process. Control..

[37]  Leon Glass,et al.  A method for detection of atrial fibrillation using RR intervals , 2000, Computers in Cardiology 2000. Vol.27 (Cat. 00CH37163).

[38]  J. Halperin,et al.  Atrial fibrillation and stroke : concepts and controversies. , 2001, Stroke.

[39]  Jonathan Rubin,et al.  Densely connected convolutional networks for detection of atrial fibrillation from short single-lead ECG recordings. , 2018, Journal of electrocardiology.

[40]  Ye Li,et al.  Multiscaled Fusion of Deep Convolutional Neural Networks for Screening Atrial Fibrillation From Single Lead Short ECG Recordings , 2018, IEEE Journal of Biomedical and Health Informatics.