Guidelines for Preventing Health-Care-Associated Pneumonia, 2003 Recommendations of the CDC and the Healthcare Infection Control Practices Advisory Committee

[1]  B. Make,et al.  Contaminated condensate in mechanical ventilator circuits. A risk factor for nosocomial pneumonia? , 1984, The American review of respiratory disease.

[2]  V. Deroin,et al.  Selective decontamination of the digestive tract in neurosurgical intensive care unit patients: A double‐blind, randomized, placebo‐controlled study , 1993, Critical care medicine.

[3]  Elder Ha,et al.  Nosocomial infection surveillance. , 1979 .

[4]  P. Savelkoul,et al.  Outbreak of Bacillus cereus Infections in a Neonatal Intensive Care Unit Traced to Balloons Used in Manual Ventilation , 2000, Journal of Clinical Microbiology.

[5]  D. Powner,et al.  Bedside Resuscitation Bags: A Source of Bacterial Contamination , 1985, Infection Control.

[6]  S. Chevret,et al.  Influence of long‐term oro‐ or nasotracheal intubation on nosocomial maxillary sinusitis and pneumonia: Results of a prospective, randomized, clinical trial , 1993, Critical care medicine.

[7]  L. Saiman,et al.  Surveillance of pharyngeal colonization: detection and control of serious bacterial illness in low birth weight infants , 1994, The Pediatric infectious disease journal.

[8]  R. Kacmarek,et al.  Weekly Ventilator Circuit Changes: A Strategy to Reduce Costs without Affecting Pneumonia Rates , 1995, Anesthesiology.

[9]  A. Streifel,et al.  Bubbling Humidifiers Produce Microaerosols Which Can Carry Bacteria , 1986, Infection Control.

[10]  K. Hyams,et al.  Multidose Medication Vial Sterility: An In-Use Study and a Review of the Literature , 1984, Infection Control.

[11]  B. Schleder,et al.  The Effect of a Comprehensive Oral Care Protocol on Patients at Risk for Ventilator-Associated Pneumonia. , 2002 .

[12]  A. Glatt,et al.  Acinetobacter calcoaceticus anitratus outbreak in the intensive care unit traced to a peak flow meter. , 1994, American journal of infection control.

[13]  A. Torres,et al.  Effect of Nasogastric Tube Size on Gastroesophageal Reflux and Microaspiration in Intubated Patients , 1999, Annals of Internal Medicine.

[14]  J Tapper,et al.  Prevention of respiratory complications after abdominal surgery: a randomised clinical trial , 1996, BMJ.

[15]  D. Nicotra,et al.  Process improvement plan for the reduction of nosocomial pneumonia in patients on ventilators. , 1996, Journal of nursing care quality.

[16]  M. Kollef,et al.  Mechanical ventilation with or without daily changes of in-line suction catheters. , 1997, American journal of respiratory and critical care medicine.

[17]  R. Rodríguez-Roisín,et al.  Pulmonary Aspiration of Gastric Contents in Patients Receiving Mechanical Ventilation: The Effect of Body Position , 1992, Annals of Internal Medicine.

[18]  J. Brooks-Brunn.  Predictors of postoperative pulmonary complications following abdominal surgery. , 1997, Chest.

[19]  R. Rodríguez-Roisín,et al.  Nosocomial pneumonia. A multivariate analysis of risk and prognosis. , 1988, Chest.

[20]  C. Truwit,et al.  Incidence of colonization, nosocomial pneumonia, and mortality in critically ill patients using a Trach Care™ closed‐suction system versus an open‐suction system: Prospective, randomized study , 1990, Critical care medicine.

[21]  E. Wong,et al.  Guideline for Prevention of Nosocomial Pneumonia , 1982, Infection Control.

[22]  M. García,et al.  Effectiveness and cost of selective decontamination of the digestive tract in critically ill intubated patients. A randomized, double-blind, placebo-controlled, multicenter trial. , 1998 .

[23]  R. Weinstein,et al.  Pilot trial of selective decontamination for prevention of bacterial infection in an intensive care unit. , 1990, The Journal of infectious diseases.

[24]  B. Nyström,et al.  Low level of bacterial contamination of mist tents used in home treatment of cystic fibrosis patients. , 2000, The Journal of hospital infection.

[25]  R. Kaul,et al.  Investigation of a multiyear multiple critical care unit outbreak due to relatively drug-sensitive Acinetobacter baumannii: risk factors and attributable mortality. , 1996, The Journal of infectious diseases.

[26]  D. Heyland,et al.  Optimizing the benefits and minimizing the risks of enteral nutrition in the critically ill: role of small bowel feeding. , 2002, JPEN. Journal of parenteral and enteral nutrition.

[27]  J. Roustan,et al.  Comparison of hydrophobic heat and moisture exchangers with heated humidifier during prolonged mechanical ventilation , 2005, Intensive Care Medicine.

[28]  B. Make,et al.  Risk factors for pneumonia and fatality in patients receiving continuous mechanical ventilation. , 1986, The American review of respiratory disease.

[29]  S. Keenan,et al.  Noninvasive positive pressure ventilation in acute respiratory failure. , 2000, JAMA.

[30]  M. Fox,et al.  Selective decontamination of the digestive tract in cardiac surgical patients , 1991, Critical care medicine.

[31]  P. Mcclelland,et al.  Reducing sepsis in severe combined acute renal and respiratory failure by selective decontamination of the digestive tract. , 1990, Critical care medicine.

[32]  M. Favero,et al.  Pseudomonas aeruginosa: Growth in Distilled Water from Hospitals , 1971, Science.

[33]  J. Rello,et al.  Continuous Aspiration of Subglottic Secretions in Preventing Ventilator-Associated Pneumonia , 1995, Annals of Internal Medicine.

[34]  Yasumasa Akagawa,et al.  Oral Care Reduces Pneumonia in Older Patients in Nursing Homes , 2002, Journal of the American Geriatrics Society.

[35]  L. Doornbos,et al.  Selective decontamination of the digestive tract with norfloxacin in the prevention of ICU-acquired infections: a prospective randomized study , 2004, Intensive Care Medicine.

[36]  Eric J. Houston,et al.  An Outbreak of Burkholderia (Formerly Pseudomonas) cepacia Respiratory Tract Colonization and Infection Associated with Nebulized Albuterol Therapy , 1995, Annals of Internal Medicine.

[37]  R. Rodríguez-Roisín,et al.  Re-intubation increases the risk of nosocomial pneumonia in patients needing mechanical ventilation. , 1995, American journal of respiratory and critical care medicine.

[38]  L. Thijs,et al.  Randomised trial of glutamine-enriched enteral nutrition on infectious morbidity in patients with multiple trauma , 1998, The Lancet.

[39]  R. Masterton,et al.  Cross infection in an intensive care unit by Klebsiella pneumoniae from ventilator condensate. , 1993, The Journal of hospital infection.

[40]  E. Shapiro,et al.  A controlled evaluation of the protective efficacy of pneumococcal vaccine for patients at high risk of serious pneumococcal infections. , 1984, Annals of internal medicine.

[41]  T. Stull,et al.  An outbreak of Burkholderia cepacia lower respiratory tract infection associated with contaminated albuterol nebulization solution. , 1996 .

[42]  D. Gruson,et al.  Rotation and restricted use of antibiotics in a medical intensive care unit. Impact on the incidence of ventilator-associated pneumonia caused by antibiotic-resistant gram-negative bacteria. , 2000, American journal of respiratory and critical care medicine.

[43]  L. Scharer,et al.  A hospital outbreak of Klebsiella pneumonia from inhalation therapy with contaminated aerosol solutions. , 1967, The American review of respiratory disease.

[44]  E. DeMaria,et al.  Role of gastric colonization in the development of pneumonia in critically ill trauma patients: results of a prospective randomized trial. , 1990, The Journal of trauma.

[45]  R. Haley,et al.  The efficacy of infection surveillance and control programs in preventing nosocomial infections in US hospitals. , 1985, American journal of epidemiology.

[46]  M. Stevens,et al.  Granulocyte colony-stimulating factor in established febrile neutropenia: a randomized study of pediatric patients. , 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[47]  Andrew M. Jones,et al.  Topical antibiotics on tracheostoma prevents exogenous colonization and infection of lower airways in children. , 2000, Chest.

[48]  Jackie Thomas,et al.  Are incentive spirometry, intermittent positive pressure breathing, and deep breathing exercises effective in the prevention of postoperative pulmonary complications after upper abdominal surgery? A systematic overview and meta-analysis. , 1994, Physical therapy.

[49]  A J DeRiso,et al.  Chlorhexidine Gluconate 0.12% Oral Rinse Reduces the Incidence of Total Nosocomial Respiratory Infection and Nonprophylactic Systemic Antibiotic Use in Patients Undergoing Heart Surgery , 1996, Chest.

[50]  W. P. Stone,et al.  Investigation of an outbreak of infection with Acinetobacter calcoaceticus in a special care baby unit. , 1986, The Journal of hospital infection.

[51]  Victoria J. Fraser,et al.  Effect of an education program aimed at reducing the occurrence of ventilator-associated pneumonia* , 2002, Critical care medicine.

[52]  J. Arends,et al.  Glutamine and the preservation of gut integrity , 1993, The Lancet.

[53]  F. K. Gould,et al.  An outbreak of Acinetobacter respiratory tract infection resulting from incomplete disinfection of ventilatory equipment. , 1990, The Journal of hospital infection.

[54]  R. Gamelli,et al.  Effect of prophylactic administration of recombinant human granulocyte colony-stimulating factor (filgrastim) on the frequency of nosocomial infections in patients with acute traumatic brain injury or cerebral hemorrhage. The Filgrastim Study Group. , 1998, Critical care medicine.

[55]  B. Rowlands,et al.  Selective decontamination of the digestive tract: a stratified, randomized, prospective study in a mixed intensive care unit. , 1991, Surgery.

[56]  C. Alex,et al.  Extending ventilator circuit change interval beyond 2 days reduces the likelihood of ventilator-associated pneumonia. , 1998, Chest.

[57]  C. Perret,et al.  Safety of combined heat and moisture exchanger filters in long-term mechanical ventilation. , 1997, Chest.

[58]  D. Craig,et al.  Disinfection of anaesthesia equipment by a mechanized pasteurization method , 1975, Canadian Anaesthetists' Society journal.

[59]  G. Ramsay,et al.  TRIPLE REGIMEN OF SELECTIVE DECONTAMINATION OF THE DIGESTIVE TRACT, SYSTEMIC CEFOTAXIME, AND MICROBIOLOGICAL SURVEILLANCE FOR PREVENTION OF ACQUIRED INFECTION IN INTENSIVE CARE , 1988, The Lancet.

[60]  P. Spirn,et al.  Inadvertent transbronchial insertion of narrow-bore feeding tubes into the pleural space. , 1984, JAMA.

[61]  M. Prato,et al.  Noninvasive Mechanical Ventilation in the Weaning of Patients with Respiratory Failure Due to Chronic Obstructive Pulmonary Disease , 1998, Annals of Internal Medicine.

[62]  A. García-de-Lorenzo,et al.  Multicenter, prospective, randomized, single-blind study comparing the efficacy and gastrointestinal complications of early jejunal feeding with early gastric feeding in critically ill patients , 2002, Critical care medicine.

[63]  O. Kirton,et al.  A prospective, randomized comparison of an in-line heat moisture exchange filter and heated wire humidifiers: rates of ventilator-associated early-onset (community-acquired) or late-onset (hospital-acquired) pneumonia and incidence of endotracheal tube occlusion. , 1997, Chest.

[64]  K. Peter,et al.  Influence of combined intravenous and topical antibiotic prophylaxis on the incidence of infections, organ dysfunctions, and mortality in critically ill surgical patients: a prospective, stratified, randomized, double-blind, placebo-controlled clinical trial. , 2002, American journal of respiratory and critical care medicine.

[65]  G. Guyatt,et al.  A comparison of sucralfate and ranitidine for the prevention of upper gastrointestinal bleeding in patients requiring mechanical ventilation. Canadian Critical Care Trials Group. , 1998, The New England journal of medicine.

[66]  C. Marsault,et al.  Risk factors and clinical relevance of nosocomial maxillary sinusitis in the critically ill. , 1994, American journal of respiratory and critical care medicine.

[67]  J. Garner,et al.  Guideline for isolation precautions in hospitals. The Hospital Infection Control Practices Advisory Committee. , 1996, Infection control and hospital epidemiology.

[68]  M. Gourdeau,et al.  Anesthesia breathing circuits protected by the DAR Barrierbac S® breathing filter have a low bacterial contamination rate , 2001, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[69]  R. Chang,et al.  Continuous enteral feeding: a major cause of pneumonia among ventilated intensive care unit patients. , 1990, JPEN. Journal of parenteral and enteral nutrition.

[70]  G. Bollin,et al.  Utilizing Quality Assurance as a Tool for Reducing the Risk of Nosocomial Ventilator-Associated Pneumonia , 1996, American journal of medical quality : the official journal of the American College of Medical Quality.

[71]  S. Chevret,et al.  A controlled trial in intensive care units of selective decontamination of the digestive tract with nonabsorbable antibiotics. The French Study Group on Selective Decontamination of the Digestive Tract. , 1992, The New England journal of medicine.

[72]  S. I. Kelleghan,et al.  An effective continuous quality improvement approach to the prevention of ventilator-associated pneumonia. , 1993, American journal of infection control.

[73]  D. Dreyfuss,et al.  Prospective study of nosocomial pneumonia and of patient and circuit colonization during mechanical ventilation with circuit changes every 48 hours versus no change. , 1991, The American review of respiratory disease.

[74]  R. C. Dennis,et al.  Nutritional outcome and pneumonia in critical care patients randomized to gastric versus jejunal tube feedings , 1992, Critical care medicine.

[75]  A. Berry,et al.  An Alternative Strategy for Infection Control of Anesthesia Breathing Circuits: A Laboratory Assessment of the Pall HME Filter , 1991, Anesthesia and analgesia.

[76]  W. Fegeler,et al.  Effect of selective flora suppression on colonization, infection, and mortality in critically ill patients: A one‐year, prospective consecutive study , 1991, Critical care medicine.

[77]  R. Rodríguez-Roisín,et al.  Semirecumbent position protects from pulmonary aspiration but not completely from gastroesophageal reflux in mechanically ventilated patients. , 1995, American journal of respiratory and critical care medicine.

[78]  F Lemaire,et al.  Intestinal decontamination for control of nosocomial multiresistant gram-negative bacilli. Study of an outbreak in an intensive care unit. , 1989, Annals of internal medicine.

[79]  C. Kirsch,et al.  The incidence of ventilator-associated pneumonia and success in nutrient delivery with gastric versus small intestinal feeding: A randomized clinical trial , 2000, Critical care medicine.

[80]  J. Marshall,et al.  Selective decontamination of the digestive tract in surgical patients: a systematic review of the evidence. , 1999, Archives of surgery.

[81]  H. Bruining,et al.  Selective decontamination to reduce gram-negative colonisation and infections after oesophageal resection , 1990, The Lancet.

[82]  W. Summer,et al.  Effect of air-supported, continuous, postural oscillation on the risk of early ICU pneumonia in nontraumatic critical illness. , 1993, Chest.

[83]  S. Allen,et al.  Effect of a rotating bed on the incidence of pulmonary complications in critically ill patients. , 1988, Critical care medicine.

[84]  M. Tryba.  Risk of acute stress bleeding and nosocomial pneumonia in ventilated intensive care unit patients: sucralfate versus antacids. , 1987, The American journal of medicine.

[85]  Didier Pittet,et al.  Guideline for Hand Hygiene in Health-Care Settings. Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HIPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. , 2002, American journal of infection control.

[86]  W. Rutala,et al.  Manual ventilation bags as a source for bacterial colonization of intubated patients. , 1990, The American review of respiratory disease.

[87]  M. Farnell,et al.  Prevention of Infection in Critically Ill Patients by Selective Decontamination of the Digestive Tract , 1992, Annals of Internal Medicine.

[88]  D. Singer,et al.  Understanding physician adherence with a pneumonia practice guideline: effects of patient, system, and physician factors. , 2000, Archives of internal medicine.

[89]  Martin L. Lee,et al.  Prophylactic intravenous administration of standard immune globulin as compared with core-lipopolysaccharide immune globulin in patients at high risk of postsurgical infection. , 1992, The New England journal of medicine.

[90]  J. de Batlle,et al.  Protective effect of intravenously administered cefuroxime against nosocomial pneumonia in patients with structural coma. , 1997, American journal of respiratory and critical care medicine.

[91]  G. T. Post,et al.  Multidose vials versus single-dose vials: a study in sterility and cost-effectiveness , 1983, Journal of clinical microbiology.

[92]  J. Maugein,et al.  Electronic ventilator temperature sensors as a potential source of respiratory tract colonization with Stenotrophomonas maltophilia. , 2001, The Journal of hospital infection.

[93]  D. Zandstra,et al.  The effect of selective decontamination of the digestive tract on colonisation and infection rate in multiple trauma patients , 2004, Intensive Care Medicine.

[94]  R. Irwin,et al.  An outbreak of acinetobacter infection associated with the use of a ventilator spirometer. , 1980, Respiratory care.

[95]  M. Wysocki,et al.  Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease. , 1995, The New England journal of medicine.

[96]  D. Yıldızdaş,et al.  Occurrence of ventilator-associated pneumonia in mechanically ventilated pediatric intensive care patients during stress ulcer prophylaxis with sucralfate, ranitidine, and omeprazole. , 2002, Journal of critical care.

[97]  H. Norton,et al.  Nosocomial pneumonia in ventilated trauma patients during stress ulcer prophylaxis with sucralfate, antacid, and ranitidine. , 1996, The Journal of trauma.

[98]  P. Potgieter,et al.  Double-blind study of selective decontamination of the digestive tract in intensive care , 1992, The Lancet.

[99]  David A Spain,et al.  North American Summit on Aspiration in the Critically Ill Patient: consensus statement. , 2002, JPEN. Journal of parenteral and enteral nutrition.

[100]  J. Festen,et al.  Clinical Investigations in Critical CareAntibiotic Prophylaxis of Respiratory Tract Infection in Mechanically Ventilated Patients: A Prospective, Blinded, Randomized Trial of the Effect of a Novel Regimen , 1991 .

[101]  Caroline C. Johnson,et al.  Immunoprophylaxis against Klebsiella and Pseudomonas aeruginosa Infections , 1996 .

[102]  Prevention of nosocomial respiratory syncytial virus infections through compliance with glove and gown isolation precautions. , 1987 .

[103]  M. Astiz,et al.  Effect of continuous lateral rotational therapy on the prevalence of ventilator-associated pneumonia in patients requiring long-term ventilatory care* , 2002, Critical care medicine.

[104]  C. Martin,et al.  Selective digestive decontamination in multiple trauma patients: Cost and efficacy , 1995, Pharmacy World and Science.

[105]  B. Plikaytis,et al.  Nosocomial Legionnaires' disease and use of medication nebulizers. , 1991, The Journal of infectious diseases.

[106]  V Torri,et al.  Effectiveness of antibiotic prophylaxis in critically ill adult patients: systematic review of randomised controlled trials , 1998, BMJ.

[107]  R. Elston,et al.  Continuous mechanical turning of intensive care unit patients shortens length of stay in some diagnostic-related groups , 1989 .

[108]  R. Strong,et al.  Equal aspiration rates from postpylorus and intragastric-placed small-bore nasoenteric feeding tubes: a randomized, prospective study. , 1992, JPEN. Journal of parenteral and enteral nutrition.

[109]  H. L. Moffet,et al.  Survival and dissemination of bacteria in nebulizers and incubators. , 1967, American journal of diseases of children.

[110]  V. Ashline,et al.  Critical care bug team: a multidisciplinary team approach to reducing ventilator-associated pneumonia. , 2000, American journal of infection control.

[111]  C. Liu,et al.  Enteral nutrition in patients receiving mechanical ventilation. Multiple sources of tracheal colonization include the stomach. , 1986, The American journal of medicine.

[112]  H. Humphreys,et al.  A controlled trial of selective decontamination of the digestive tract in intensive care and its effect on nosocomial infection. , 1992, The Journal of antimicrobial chemotherapy.

[113]  K. Nichol,et al.  Immunizations in Long‐Term Care Facilities: Policies and Practice , 1996, Journal of the American Geriatrics Society.

[114]  H. Grieble,et al.  Fine-particle humidifiers. Source of Pseudomonas aeruginosa infections in a respiratory-disease unit. , 1970, The New England journal of medicine.

[115]  R. Garibaldi,et al.  Failure of bacterial filters to reduce the incidence of pneumonia after inhalation anesthesia. , 1981 .

[116]  G. Ford,et al.  Multipatient use of prefilled disposable oxygen humidifiers for up to 30 days: patient safety and cost analysis. , 1993, Respiratory care.

[117]  L. Brochard,et al.  Association of noninvasive ventilation with nosocomial infections and survival in critically ill patients. , 2000, JAMA.

[118]  J. Miles,et al.  Contaminated aerosol recovery from pulmonary function testing equipment. , 1999, American journal of respiratory and critical care medicine.

[119]  J. Fierer,et al.  Pseudomonas aeruginosa epidemic traced to delivery-room resuscitators. , 1967, The New England journal of medicine.

[120]  M. Fink,et al.  The efficacy of an oscillating bed in the prevention of lower respiratory tract infection in critically ill victims of blunt trauma. A prospective study. , 1990, Chest.

[121]  A. Corrado,et al.  Bleeding and pneumonia in intensive care patients given ranitidine and sucralfate for prevention of stress ulcer: meta-analysis of randomised controlled trials , 2000, BMJ : British Medical Journal.

[122]  K. Yuen,et al.  Evaluating the sterility of disposable wall oxygen humidifiers, during and between use on patients. , 1990 .

[123]  P Gastmeier,et al.  [Guidelines for preventing health-care-associated pneumonia]. , 2005, Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS.

[124]  A. Saubermann,et al.  The Anesthesia Machine and Circle System Are Not Likely to be Sources of Bacterial Contamination , 1977, Anesthesiology.

[125]  Y. Cohen,et al.  Mechanical ventilation with heated humidifiers or heat and moisture exchangers: effects on patient colonization and incidence of nosocomial pneumonia. , 1995, American journal of respiratory and critical care medicine.

[126]  Stress ulcer prophylaxis in critically ill patients. Resolving discordant meta-analyses. , 1996 .

[127]  M. Kollef,et al.  Scheduled change of antibiotic classes: a strategy to decrease the incidence of ventilator-associated pneumonia. , 1997, American journal of respiratory and critical care medicine.

[128]  P. Arnow,et al.  Nosocomial Legionnaires' disease caused by aerosolized tap water from respiratory devices. , 1982, The Journal of infectious diseases.

[129]  T. Sundt,et al.  A randomized clinical trial of continuous aspiration of subglottic secretions in cardiac surgery patients. , 1999, Chest.

[130]  D. Cook,et al.  Influence of airway management on ventilator-associated pneumonia: evidence from randomized trials. , 1998, JAMA.

[131]  C. Martin,et al.  Comparing two heat and moisture exchangers, one hydrophobic and one hygroscopic, on humidifying efficacy and the rate of nosocomial pneumonia. , 1998, Chest.

[132]  M. Zervos,et al.  Association of contaminated gloves with transmission of Acinetobacter calcoaceticus var. anitratus in an intensive care unit. , 1991, The American journal of medicine.

[133]  P. D. de Leeuw,et al.  Intermittent enteral feeding: the influence on respiratory and digestive tract colonization in mechanically ventilated intensive-care-unit patients. , 1996, American journal of respiratory and critical care medicine.

[134]  M. Wysocki,et al.  Noninvasive versus conventional mechanical ventilation. An epidemiologic survey. , 2001, American journal of respiratory and critical care medicine.

[135]  M. Keroack,et al.  Cost analysis and clinical impact of weekly ventilator circuit changes in patients in intensive care unit. , 1997, American journal of infection control.

[136]  R. Rodríguez-Roisín,et al.  Utility of Selective Digestive Decontamination in Mechanically Ventilated Patients , 1994, Annals of Internal Medicine.