Level prediction of preterm birth using risk factor analysis and electrohysterogram signal classification

As per the reports published by World Health Organization (WHO) in November, 2012, every year more than 15 million babies are born preterm and this number is rising [1]. Preterm labor is the major cause of neonatal deaths. Every year, pre term birth (PTB) complications leads to the death of almost 1 million babies [2][3]. Predicting the preterm labor well in advance can reduce the neonatal death considerably. There are some commonly attributed risk factors associated with preterm birth [4][5]. 33% of the women who deliver their babies prematurely have one or more of these risk factors. We propose to predict PTB by analyzing the historical data of patients who had one or more of the above risk factors. In addition to this, historic data of the patients who did not have any of the above risk factors but had PTB is also analyzed. Electrohysterogram (EHG) is the most commonly used clinical procedure which can reveal few indicators of preterm labor [6]. We analyze the EHG signals to predict the pre term labor by applying Feature Extraction coupled with semi-supervised learning (SSL). Predicting the preterm labor helps the health care professionals to make decisions about the treatment [7]. Hence the expectant mother undergoes minimal or no complications of preterm labor. On the other hand it also helps to avoid unnecessary hospitalization and treatment for women who are having a false labor pain.

[1]  Jeffrey M. Hausdorff,et al.  Physionet: Components of a New Research Resource for Complex Physiologic Signals". Circu-lation Vol , 2000 .

[2]  S. Jawaid The Global Action Report on Preterm Birth , 2012 .

[3]  Abraham Frandsen Machine Learning for Disease Prediction , 2016 .

[4]  F. Mohd-Yasin,et al.  Techniques of EMG signal analysis: detection, processing, classification and applications , 2006, Biological Procedures Online.

[5]  Christina Catley,et al.  Predicting High-Risk Preterm Birth Using Artificial Neural Networks , 2006, IEEE Transactions on Information Technology in Biomedicine.

[6]  Kayvan Najarian,et al.  Big Data Analytics in Healthcare , 2015, BioMed research international.

[7]  Chelsea Dobbins,et al.  Advanced artificial neural network classification for detecting preterm births using EHG records , 2016, Neurocomputing.

[8]  G. D. Di Renzo,et al.  Guidelines for the management of spontaneous preterm labor , 2006, Journal of perinatal medicine.

[9]  ÜbeyliElif Derya,et al.  Wavelet transform feature extraction from human PPG, ECG, and EEG signal responses to ELF PEMF exposures , 2008 .

[10]  N. E. Beltagy,et al.  Risk Factors for Preterm Labor among Women Attending El Shatby Maternity University Hospital, Alexandria, Egypt , 2016 .

[11]  Dhiya Al-Jumeily,et al.  Applied Computing in Medicine and Health , 2015 .

[12]  Yijun Wang,et al.  Common Spatial Pattern Method for Channel Selelction in Motor Imagery Based Brain-computer Interface , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[13]  T. Diseth,et al.  Mental health in women experiencing preterm birth , 2014, BMC Pregnancy and Childbirth.

[14]  Mohamed A. A. Eldosoky,et al.  New technique based on uterine electromyography nonlinearity for preterm delivery detection , 2014 .

[15]  J. Martin,et al.  Born a bit too early: recent trends in late preterm births. , 2009, NCHS data brief.

[16]  Songmin Jia,et al.  Optimal combination of channels selection based on common spatial pattern algorithm , 2011, 2011 IEEE International Conference on Mechatronics and Automation.

[17]  J. Zeitlin,et al.  International comparisons of infant mortality and related factors: United States and Europe, 2010. , 2014, National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System.

[18]  Elif Derya Übeyli,et al.  Wavelet transform feature extraction from human PPG, ECG, and EEG signal responses to ELF PEMF exposures: A pilot study , 2008, Digit. Signal Process..

[19]  Massimo Mischi,et al.  Study protocol: PoPE-Prediction of Preterm delivery by Electrohysterography , 2014, BMC Pregnancy and Childbirth.