Evidence from the use of vibration during procaine nerve block that the spindle group II fibres contribute excitation to the tonic stretch reflex of the decerebrate cat

1. Experiments have been performed to test the hypothesis that the group II fibres from the secondary endings of the muscle spindle provide an excitatory contribution to the tonic stretch reflex of the decerebrate cat. They have consisted of studying the effect of fusimotor paralysis by procaine, applied to the muscle nerve, on the reflex response to the combined stimuli of stretch (5–9 mm at 5 mm/sec) and of high‐frequency vibration (100–150 Hz, 150 μm).

[1]  P. Matthews,et al.  Mammalian muscle receptors and their central actions , 1974 .

[2]  P. Matthews,et al.  The use of repetitively applied sharply rising mechanical pulses to excite spindle primary endings and thus minimize the 'double driving' occasionally produced by high frequency sinusoidal stretching. , 1973, The Journal of physiology.

[3]  P. Matthews,et al.  The relative sensitivity of muscle nerve fibres to procaine , 1957, The Journal of physiology.

[4]  D. Westbury,et al.  A study of stretch and vibration reflexes of the cat by intracellular recording from motoneurones , 1972, The Journal of physiology.

[5]  O. Pompeiano,et al.  An apparatus for producing small-amplitude high-frequency sinusoidal stretching of the muscle. , 1970, Archives italiennes de biologie.

[6]  P. Matthews,et al.  The regularity of primary and secondary muscle spindle afferent discharges , 1969, The Journal of physiology.

[7]  P. Matthews,et al.  The effects of fusimotor activity on the static responsiveness of primary and secondary endings of muscle spindles in the decerebrate cat. , 1962, Acta physiologica Scandinavica.

[8]  O. Pompeiano,et al.  Evidence that presynaptic inhibition may decrease the autogenetic excitation caused by vibration of extensor muscles. , 1972, Archives italiennes de biologie.

[9]  R. Miledi,et al.  Failure of neuromuscular propagation in rats , 1958, The Journal of physiology.

[10]  S Grillner,et al.  Is the tonic stretch reflex dependent upon group II excitation? , 1970, Acta physiologica Scandinavica.

[11]  P. Matthews,et al.  The reflex excitation of the soleus muscle of the decerebrate cat caused by vibration applied to its tendon , 1966, The Journal of physiology.

[12]  P. Matthews,et al.  The tonic vibration reflex seen in the acute spinal cat after treatment with DOPA. , 1973, Brain research.

[13]  P. Matthews.  Evidence that the secondary as well as the primary endings of the muscle spindles may be responsible for the tonic stretch reflex of the decerebrate cat , 1969, The Journal of physiology.

[14]  A. Cangiano,et al.  The action of selectively activated group II muscle afferent fibers on extensor motoneurons. , 1972, Brain research.

[15]  P. Matthews.  The effect of the local application of procaine on the stretch reflex of the soleus muscle of the cat decerebrated by anaemia , 1958, The Journal of physiology.

[16]  P. Matthews,et al.  The discharge from muscle spindles as an indicator of γ‐efferent paralysis by procaine , 1958, The Journal of Physiology.

[17]  C. D. MARSDEN,et al.  Servo Action in Human Voluntary Movement , 1972, Nature.

[18]  P. Matthews,et al.  The selective effect of procaine on the stretch reflex and tendon jerk of soleus muscle when applied to its nerve , 1957, The Journal of physiology.

[19]  A. Paintal,et al.  Block of conduction in mammalian myelinated nerve fibres by low temperatures. , 1965, The Journal of physiology.

[20]  W A Cook,et al.  Contribution of group I afferents to the tonic stretch reflex of the decerebrate cat. , 1971, Brain research.

[21]  P. Matthews,et al.  Support for an autogenetic excitatory reflex action of the spindle secondaries from the effect of gamma blockade by procaine. , 1970, Journal of Physiology.

[22]  G. C. Joyce,et al.  The mechanical properties of cat soleus muscle during controlled lengthening and shortening movements , 1969, The Journal of physiology.

[23]  S. Grillner.  The role of muscle stiffness in meeting the changing postural and locomotor requirements for force development by the ankle extensors. , 1972, Acta physiologica Scandinavica.

[24]  P. Matthews,et al.  The relative sensitivity to vibration of muscle receptors of the cat , 1967, The Journal of physiology.

[25]  Y. Laporte,et al.  Absence de réflexe myotatique après blocage de la conduction dans les fibres du groupe. , 1972 .

[26]  R. Miledi,et al.  Presynaptic failure of neuromuscular propagation in rats , 1959, The Journal of physiology.

[27]  S. Skoglund.  On the Postnatal Development of Postural Mechanisms as Revealed by Electromyography and Myography in Decerebrate Kittens , 1960 .

[28]  P. Matthews,et al.  A reply to criticism of the hypothesis that the group II afferents contribute excitation to the stretch reflex. , 1970, Acta physiologica Scandinavica.