Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole.
暂无分享,去创建一个
Eric Oldfield | E. Oldfield | J. Concepción | J. Urbina | M. Levin | A. Schijman | J. Sanders | John M Sanders | Julio A Urbina | Y. García-Marchán | G. Benaim | Claudia Colina | Gustavo Benaim | Juan Luis Concepcion | Gilberto Payares | Cristina Sanoja | Yael Garcia-Marchán | Renee Lira | Aura R Caldera | Juan Miguel Burgos | Annette Leon-Rossell | Alejandro G Schijman | Mariano Levin | C. Colina | G. Payares | J. Burgos | C. Sanoja | R. Lira | A. Caldera | Annette Leon-Rossell
[1] J. C. Hinshaw,et al. Oxidosqualene cyclase inhibitors as antimicrobial agents. , 2003, Journal of medicinal chemistry.
[2] W. de Souza,et al. Ultrastructural alterations induced by ICI 195,739, a bis-triazole derivative with strong antiproliferative action against Trypanosoma (Schizotrypanum) cruzi , 1991, Antimicrobial Agents and Chemotherapy.
[3] G. Schulz,et al. Binding structures and potencies of oxidosqualene cyclase inhibitors with the homologous squalene-hopene cyclase. , 2003, Journal of medicinal chemistry.
[4] Suggested guidelines for work with live Trypanosoma cruzi. , 1983, Transactions of the Royal Society of Tropical Medicine and Hygiene.
[5] A. De Maio,et al. Trypanosoma (Schizotrypanum) cruzi: terminal oxidases in exponential and stationary growth phase emipastigotes cultured in vitro. , 1984, Acta cientifica venezolana.
[6] D. Loebenberg,et al. Activities of the Triazole Derivative SCH 56592 (Posaconazole) against Drug-Resistant Strains of the Protozoan ParasiteTrypanosoma (Schizotrypanum) cruzi in Immunocompetent and Immunosuppressed Murine Hosts , 2000, Antimicrobial Agents and Chemotherapy.
[7] R. Favaloro,et al. Early diagnosis of recurrence of Trypanosoma cruzi infection by polymerase chain reaction after heart transplantation of a chronic Chagas' heart disease patient. , 2000, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
[8] D S Goodsell,et al. Automated docking of flexible ligands: Applications of autodock , 1996, Journal of molecular recognition : JMR.
[9] A. Rassi,et al. Chagas' Heart Disease , 2000, Clinical cardiology.
[10] AMIODARONE , 1979, The Lancet.
[11] H. Hallander,et al. Synergism between aminoglycosides and cephalosporins with antipseudomonal activity: interaction index and killing curve method , 1982, Antimicrobial Agents and Chemotherapy.
[12] R. Dipolo,et al. Evaluation of the Presence of a Thapsigargin-Sensitive Calcium Store in Trypanosomatids Using Trypanosoma evansi as a Model , 2004, The Journal of parasitology.
[13] Sedide B. Ozturk,et al. Amiodarone induces a caffeine‐inhibited, MID1‐depedent rise in free cytoplasmic calcium in Saccharomyces cerevisiae , 2002, Molecular microbiology.
[14] R. Dipolo,et al. Ceramide increase cytoplasmic Ca2+ concentration in Jurkat T cells by liberation of calcium from intracellular stores and activation of a store-operated calcium channel. , 2005, Archives of biochemistry and biophysics.
[15] P. Wincker,et al. Cure of Short- and Long-Term Experimental Chagas' Disease Using D0870 , 1996, Science.
[16] J. Dias. Control of Chagas disease in Brazil. , 1987, Parasitology today.
[17] W. Courchesne. Characterization of a novel, broad-based fungicidal activity for the antiarrhythmic drug amiodarone. , 2002, The Journal of pharmacology and experimental therapeutics.
[18] M. Ward,et al. Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts , 2000, Trends in Neurosciences.
[19] W. de Souza,et al. Ultrastructural alterations induced by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi , 1990, Antimicrobial Agents and Chemotherapy.
[20] Y. Yamagata,et al. Control of Chagas disease. , 2006, Advances in parasitology.
[21] E. Oldfield,et al. Bisphosphonates Are Potent Inhibitors of Trypanosoma cruzi Farnesyl Pyrophosphate Synthase* , 2001, The Journal of Biological Chemistry.
[22] J. Urbina,et al. Specific chemotherapy of Chagas disease: controversies and advances. , 2003, Trends in parasitology.
[23] J. Concepción,et al. In Vitro and In Vivo Activities of E5700 and ER-119884, Two Novel Orally Active Squalene Synthase Inhibitors, against Trypanosoma cruzi , 2004, Antimicrobial Agents and Chemotherapy.
[24] Y. Paik,et al. Pharmacological Analysis of Sterol Δ8-Δ7 Isomerase Proteins with [3H]Ifenprodil , 1998 .
[25] P. Wincker,et al. Antiproliferative Effects and Mechanism of Action of SCH 56592 against Trypanosoma (Schizotrypanum)cruzi: In Vitro and In Vivo Studies , 1998, Antimicrobial Agents and Chemotherapy.
[26] E. Krajewska-Kułak,et al. Effects of the combination of ketoconazole and calcium channel antagonists against Candida albicans in vitro. , 1993, Arzneimittel-Forschung.
[27] R. Courtney,et al. Pharmacokinetics, Safety, and Tolerability of Oral Posaconazole Administered in Single and Multiple Doses in Healthy Adults , 2003, Antimicrobial Agents and Chemotherapy.
[28] J. Concepción,et al. Squalene synthase as a chemotherapeutic target in Trypanosoma cruzi and Leishmania mexicana. , 2002, Molecular and biochemical parasitology.
[29] P. Verweij,et al. Potent Synergistic In Vitro Interaction between Nonantimicrobial Membrane-Active Compounds and Itraconazole against Clinical Isolates of Aspergillus fumigatus Resistant to Itraconazole , 2004, Antimicrobial Agents and Chemotherapy.
[30] David S. Goodsell,et al. Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function , 1998, J. Comput. Chem..
[31] E. H. Fife. 4 – Trypanosoma (Schizotrypanum) cruzi , 1977 .
[32] T. Schulz-Gasch,et al. Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase , 2004, Nature.
[33] D. Loebenberg,et al. Posaconazole Is a Potent Inhibitor of Sterol 14α-Demethylation in Yeasts and Molds , 2004, Antimicrobial Agents and Chemotherapy.
[34] Veronica G. Beaudry,et al. Antifungal Activity of Amiodarone Is Mediated by Disruption of Calcium Homeostasis* , 2003, Journal of Biological Chemistry.