Autophagy Reduces Neuronal Damage and Promotes Locomotor Recovery via Inhibition of Apoptosis After Spinal Cord Injury in Rats

[1]  A. Davey,et al.  Inhibition of autophagy by 3-methyladenine protects 1321N1 astrocytoma cells against pyocyanin- and 1-hydroxyphenazine-induced toxicity , 2012, Archives of Toxicology.

[2]  R. Giffard,et al.  Astrocyte Proliferation Following Stroke in the Mouse Depends on Distance from the Infarct , 2011, PloS one.

[3]  M. J. Korn,et al.  Astrocyte-Secreted Factors Modulate a Gradient of Primary Dendritic Arbors in Nucleus Laminaris of the Avian Auditory Brainstem , 2011, PloS one.

[4]  S. Anderson,et al.  Clonal Production and Organization of Inhibitory Interneurons in the Neocortex , 2011, Science.

[5]  P. Kochanek,et al.  Autophagy in acute brain injury: Feast, famine, or folly? , 2011, Neurobiology of Disease.

[6]  S. Sasaki Autophagy in Spinal Cord Motor Neurons in Sporadic Amyotrophic Lateral Sclerosis , 2011, Journal of neuropathology and experimental neurology.

[7]  G. Brewer,et al.  Autophagy in aging and Alzheimer's disease: pathologic or protective? , 2011, Journal of Alzheimer's disease : JAD.

[8]  B. Zhivotovsky,et al.  Cell cycle and cell death in disease: past, present and future , 2010, Journal of internal medicine.

[9]  S. Rangaraju,et al.  Rapamycin Activates Autophagy and Improves Myelination in Explant Cultures from Neuropathic Mice , 2010, The Journal of Neuroscience.

[10]  C. Chu A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease. , 2010, Human molecular genetics.

[11]  M. Russo,et al.  The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy , 2010, Cell Death and Differentiation.

[12]  T. Ogihara,et al.  Alzheimer Disease–Associated Peptide, Amyloid &bgr;40, Inhibits Vascular Regeneration With Induction of Endothelial Autophagy , 2009, Arteriosclerosis, thrombosis, and vascular biology.

[13]  J. Puyal,et al.  Postischemic treatment of neonatal cerebral ischemia should target autophagy , 2009, Annals of neurology.

[14]  Gyan Bhanot,et al.  Autophagy Suppresses Tumorigenesis through Elimination of p62 , 2009, Cell.

[15]  Z. Chi,et al.  Autophagy is upregulated in rats with status epilepticus and partly inhibited by Vitamin E. , 2009, Biochemical and biophysical research communications.

[16]  G. Buonocore,et al.  Protective role of autophagy in neonatal hypoxia–ischemia induced brain injury , 2008, Neurobiology of Disease.

[17]  K. Wada,et al.  Aberrant Interaction between Parkinson Disease-associated Mutant UCH-L1 and the Lysosomal Receptor for Chaperone-mediated Autophagy* , 2008, Journal of Biological Chemistry.

[18]  Brian Spencer,et al.  The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. , 2008, The Journal of clinical investigation.

[19]  John L Cleveland,et al.  Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes , 2008, Autophagy.

[20]  S. Steiger,et al.  Focal cerebral ischemia induces upregulation of Beclin 1 and autophagy-like cell death , 2008, Neurobiology of Disease.

[21]  Guido Kroemer,et al.  Autophagy in the Pathogenesis of Disease , 2008, Cell.

[22]  Ralph A. Nixon,et al.  Autophagy, amyloidogenesis and Alzheimer disease , 2007, Journal of Cell Science.

[23]  G. Bjørkøy,et al.  p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy* , 2007, Journal of Biological Chemistry.

[24]  D. Klionsky,et al.  Autophagy and Human Disease , 2007, Cell cycle.

[25]  K. Takenaga,et al.  3-Methyladenine suppresses cell migration and invasion of HT1080 fibrosarcoma cells through inhibiting phosphoinositide 3-kinases independently of autophagy inhibition. , 2007, International journal of oncology.

[26]  E. Shohami,et al.  Rapamycin is a neuroprotective treatment for traumatic brain injury , 2007, Neurobiology of Disease.

[27]  E. Shohami,et al.  Neurodegeneration Induces Upregulation of Beclin 1 , 2006, Autophagy.

[28]  J. Rothman,et al.  triggered by the insulin-signaling pathway , 2006 .

[29]  Terje Johansen,et al.  p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death , 2005, The Journal of cell biology.

[30]  C. Ross,et al.  What is the role of protein aggregation in neurodegeneration? , 2005, Nature Reviews Molecular Cell Biology.

[31]  Liat Mizrachy,et al.  Closed head injury induces upregulation of Beclin 1 at the cortical site of injury. , 2005, Journal of neurotrauma.

[32]  S. Gupta,et al.  HSP60, Bax, Apoptosis and the Heart , 2005, Journal of cellular and molecular medicine.

[33]  N. Mizushima Methods for monitoring autophagy. , 2004, The international journal of biochemistry & cell biology.

[34]  K. Matsuoka,et al.  3-methyladenine inhibits autophagy in tobacco culture cells under sucrose starvation conditions. , 2004, Plant & cell physiology.

[35]  M. Matsui,et al.  In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. , 2003, Molecular biology of the cell.

[36]  P. Mathews,et al.  The Endosomal-Lysosomal System of Neurons in Alzheimer's Disease Pathogenesis: A Review , 2000, Neurochemical Research.

[37]  S. Korsmeyer,et al.  Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death , 2001, Science.

[38]  J C Reed,et al.  Bax directly induces release of cytochrome c from isolated mitochondria. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[39]  Dean P. Jones,et al.  Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked , 1997, Science.

[40]  Michael S. Beattie,et al.  Graded Histological and Locomotor Outcomes after Spinal Cord Contusion Using the NYU Weight-Drop Device versus Transection , 1996, Experimental Neurology.

[41]  T R Holford,et al.  MASCIS evaluation of open field locomotor scores: effects of experience and teamwork on reliability. Multicenter Animal Spinal Cord Injury Study. , 1996, Journal of neurotrauma.

[42]  E. Wolvetang,et al.  3-Methyladenine, an inhibitor of autophagy, has multiple effects on metabolism. , 1988, European journal of biochemistry.

[43]  S. Sehgal,et al.  Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization.:II. FERMENTATION, ISOLATION AND CHARACTERIZATION , 1975 .