Two Amino Acid Substitutions within the First External Loop of CCR5 Induce Human Immunodeficiency Virus-Blocking Antibodies in Mice and Chickens
暂无分享,去创建一个
L. Lopalco | G. Colombo | R. Longhi | R. Consonni | C. Pastori | Giacomo M. S. De Mori | L. Diomede | A. Clivio
[1] G. Fields,et al. Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids. , 2009, International journal of peptide and protein research.
[2] John P. Moore,et al. Antiretroviral drug-based microbicides to prevent HIV-1 sexual transmission. , 2008, Annual review of medicine.
[3] R. Stevens,et al. High-Resolution Crystal Structure of an Engineered Human β2-Adrenergic G Protein–Coupled Receptor , 2007, Science.
[4] R. Stevens,et al. GPCR Engineering Yields High-Resolution Structural Insights into β2-Adrenergic Receptor Function , 2007, Science.
[5] M. Burghammer,et al. Crystal structure of the human β2 adrenergic G-protein-coupled receptor , 2007, Nature.
[6] J. Irving,et al. Peptide mimotopes selected with HIV‐1‐blocking monoclonal antibodies against CCR5 represent motifs specific for HIV‐1 entry , 2007, Immunology and cell biology.
[7] Peter D. Kwong,et al. Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4 , 2007, Science.
[8] M. Colvin,et al. The epidemiology of HIV in South African workplaces , 2007, AIDS.
[9] L. Lopalco,et al. Natural mucosal antibodies reactive with first extracellular loop of CCR5 inhibit HIV-1 transport across human epithelial cells , 2007, AIDS.
[10] L. Lopalco,et al. Long-lasting CCR5 internalization by antibodies in a subset of long-term nonprogressors: a possible protective effect against disease progression. , 2006, Blood.
[11] Gerrit Groenhof,et al. GROMACS: Fast, flexible, and free , 2005, J. Comput. Chem..
[12] Shrikant Deshpande,et al. Production of human monoclonal antibody in eggs of chimeric chickens , 2005, Nature Biotechnology.
[13] L. Lopalco,et al. Induction of Murine Mucosal CCR5-Reactive Antibodies as an Anti-Human Immunodeficiency Virus Strategy , 2005, Journal of Virology.
[14] L. Lopalco,et al. Predictive value of anti-cell and anti-human immunodeficiency virus (HIV) humoral responses in HIV-1-exposed seronegative cohorts of European and Asian origin. , 2005, The Journal of general virology.
[15] Xiaohong Wang,et al. Selection of active ScFv to G-protein-coupled receptor CCR5 using surface antigen-mimicking peptides. , 2004, Biochemistry.
[16] L. Lopalco,et al. CCR5-specific mucosal IgA in saliva and genital fluids of HIV-exposed seronegative subjects. , 2004, Blood.
[17] L. Lopalco. Humoral immunity in HIV-1 exposure: cause or effect of HIV resistance? , 2004, Current HIV research.
[18] Alfonso Valencia,et al. Identification of amino acid residues crucial for chemokine receptor dimerization , 2004, Nature Immunology.
[19] J. Binley,et al. Redox-Triggered Infection by Disulfide-Shackled Human Immunodeficiency Virus Type 1 Pseudovirions , 2003, Journal of Virology.
[20] M. Paterlini,et al. Structure modeling of the chemokine receptor CCR5: implications for ligand binding and selectivity. , 2002, Biophysical journal.
[21] L. Lopalco,et al. Serum IgA of HIV-exposed uninfected individuals inhibit HIV through recognition of a region within the α-helix of gp41 , 2002, AIDS.
[22] Q. Sattentau,et al. Occupancy and mechanism in antibody-mediated neutralization of animal viruses. , 2002, The Journal of general virology.
[23] M. Alizon,et al. Determinants of the trans-Dominant Negative Effect of Truncated Forms of the CCR5 Chemokine Receptor* , 2001, The Journal of Biological Chemistry.
[24] C. Martínez-A,et al. HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[25] L. Lopalco,et al. CCR5-Reactive Antibodies in Seronegative Partners of HIV-Seropositive Individuals Down-Modulate Surface CCR5 In Vivo and Neutralize the Infectivity of R5 Strains of HIV-1 In Vitro1 , 2000, The Journal of Immunology.
[26] Paola Fusi,et al. A single-point mutation in the extreme heat- and pressure-resistant sso7d protein from sulfolobus solfataricus leads to a major rearrangement of the hydrophobic core. , 1999, Biochemistry.
[27] J. Lisziewicz,et al. Control of HIV despite the discontinuation of antiretroviral therapy. , 1999, The New England journal of medicine.
[28] X. Daura,et al. Peptide Folding: When Simulation Meets Experiment , 1999 .
[29] J. Sodroski,et al. A Tyrosine-Rich Region in the N Terminus of CCR5 Is Important for Human Immunodeficiency Virus Type 1 Entry and Mediates an Association between gp120 and CCR5 , 1998, Journal of Virology.
[30] H. Schuitemaker,et al. Infectious Cellular Load in Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Individuals and Susceptibility of Peripheral Blood Mononuclear Cells from Their Exposed Partners to Non-Syncytium-Inducing HIV-1 as Major Determinants for HIV-1 Transmission in Homosexual Couples , 1998, Journal of Virology.
[31] William C. Olson,et al. Amino-Terminal Substitutions in the CCR5 Coreceptor Impair gp120 Binding and Human Immunodeficiency Virus Type 1 Entry , 1998, Journal of Virology.
[32] Marc Parmentier,et al. The Second Extracellular Loop of CCR5 Is the Major Determinant of Ligand Specificity* , 1997, The Journal of Biological Chemistry.
[33] Q. Sattentau,et al. Relevance of the antibody response against human immunodeficiency virus type 1 envelope to vaccine design. , 1997, Immunology letters.
[34] J. Moore. Coreceptors--Implications for HIV Pathogenesis and Therapy , 1997, Science.
[35] J. Cohen. Exploiting the HIV-Chemokine Nexus , 1997, Science.
[36] P. Argos,et al. Knowledge‐based protein secondary structure assignment , 1995, Proteins.
[37] R. Connor,et al. Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes. , 1995, Virology.
[38] G. Wagner,et al. Recognition of DNA by GAL4 in solution: use of a monomeric protein-DNA complex for study by NMR. , 1994, Biochemistry.
[39] V. Saudek,et al. Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions , 1992, Journal of biomolecular NMR.
[40] P. Kollman,et al. Settle: An analytical version of the SHAKE and RATTLE algorithm for rigid water models , 1992 .
[41] F. Richards,et al. The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy. , 1992, Biochemistry.
[42] D. King,et al. A cleavage method which minimizes side reactions following Fmoc solid phase peptide synthesis. , 1990, International journal of peptide and protein research.
[43] K. Wüthrich. NMR of proteins and nucleic acids , 1988 .
[44] T. Straatsma,et al. THE MISSING TERM IN EFFECTIVE PAIR POTENTIALS , 1987 .
[45] S W Englander,et al. Main-chain-directed strategy for the assignment of 1H NMR spectra of proteins. , 1987, Biochemistry.
[46] H. Berendsen,et al. Molecular dynamics with coupling to an external bath , 1984 .
[47] K. Wüthrich,et al. Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins. , 1983, Biochemical and biophysical research communications.
[48] W. Delano. The PyMOL Molecular Graphics System , 2002 .
[49] C. Martínez-A,et al. Chemokine signaling and functional responses: the role of receptor dimerization and TK pathway activation. , 2001, Annual review of immunology.
[50] J. Farber,et al. Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. , 1999, Annual review of immunology.
[51] Alan E. Mark,et al. The GROMOS96 Manual and User Guide , 1996 .
[52] J. Sedlák,et al. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. , 1968, Analytical biochemistry.