Human intestinal fluid factors affecting intestinal drug permeation in vitro
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[1] Clive G. Wilson,et al. Statistical investigation of simulated fed intestinal media composition on the equilibrium solubility of oral drugs , 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[2] P. Baatsen,et al. An In-Depth View into Human Intestinal Fluid Colloids: Intersubject Variability in Relation to Composition. , 2016, Molecular pharmaceutics.
[3] J. Tack,et al. In vitro and in vivo investigation of the gastrointestinal behavior of simvastatin. , 2016, International journal of pharmaceutics.
[4] G. Duchateau,et al. Pharmaceutics, Drug Delivery and Pharmaceutical Technology Characterization of Human Duodenal Fluids in Fasted and Fed State Conditions , 2016 .
[5] A. Müllertz,et al. Structural features of colloidal species in the human fasted upper small intestine , 2015, The Journal of pharmacy and pharmacology.
[6] J. Tack,et al. Evaluation of fasted and fed state simulated and human intestinal fluids as solvent system in the Ussing chambers model to explore food effects on intestinal permeability. , 2015, International journal of pharmaceutics.
[7] J. Tack,et al. Evaluation of fasted state human intestinal fluid as apical solvent system in the Caco-2 absorption model and comparison with FaSSIF. , 2015, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[8] Clive G. Wilson,et al. Statistical investigation of simulated intestinal fluid composition on the equilibrium solubility of biopharmaceutics classification system class II drugs. , 2015, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[9] J. Dressman,et al. Composition and physicochemical properties of fasted-state human duodenal and jejunal fluid: a critical evaluation of the available data. , 2014, Journal of pharmaceutical sciences.
[10] J. Tack,et al. Human and simulated intestinal fluids as solvent systems to explore food effects on intestinal solubility and permeability. , 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[11] Mark McAllister,et al. Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs. , 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[12] Bart Hens,et al. A review of drug solubility in human intestinal fluids: implications for the prediction of oral absorption. , 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[13] C. Reppas,et al. Biorelevant media for transport experiments in the Caco-2 model to evaluate drug absorption in the fasted and the fed state and their usefulness. , 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[14] A. Müllertz,et al. Unravelling the ultrastructure of ascending colon fluids from patients with ulcerative colitis by cryogenic transmission electron microscopy , 2013, The Journal of pharmacy and pharmacology.
[15] J. Tack,et al. Exploring food effects on indinavir absorption with human intestinal fluids in the mouse intestine. , 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[16] P. Tso,et al. Intestinal bile secretion promotes drug absorption from lipid colloidal phases via induction of supersaturation. , 2013, Molecular pharmaceutics.
[17] C. Reppas,et al. Luminal lipid phases after administration of a triglyceride solution of danazol in the fed state and their contribution to the flux of danazol across Caco-2 cell monolayers. , 2012, Molecular pharmaceutics.
[18] Anette Müllertz,et al. Insights into intermediate phases of human intestinal fluids visualized by atomic force microscopy and cryo-transmission electron microscopy ex vivo. , 2012, Molecular pharmaceutics.
[19] G. Amidon,et al. The solubility-permeability interplay: mechanistic modeling and predictive application of the impact of micellar solubilization on intestinal permeation. , 2011, Molecular pharmaceutics.
[20] G. Duchateau,et al. Postprandial Changes in Solubilizing Capacity of Human Intestinal Fluids for BCS Class II Drugs , 2009, Pharmaceutical Research.
[21] P Augustijns,et al. Postprandial evolution in composition and characteristics of human duodenal fluids in different nutritional states. , 2009, Journal of pharmaceutical sciences.
[22] Patrick Augustijns,et al. Characterization of fasted‐state human intestinal fluids collected from duodenum and jejunum , 2006, The Journal of pharmacy and pharmacology.
[23] P. Augustijns,et al. Apricot extract inhibits the P-gp-mediated efflux of talinolol. , 2002, Journal of pharmaceutical sciences.