Epidemiology and molecular genetics of colorectal cancer.
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[1] J. Hecht. Metastasis in colorectal cancer: what makes the tumor aggressive? , 2003, The European journal of surgery. Supplement. : = Acta chirurgica. Supplement.
[2] J. Potter,et al. Colorectal cancer: molecules and populations. , 1999, Journal of the National Cancer Institute.
[3] John Calvin Reed,et al. Impairment of the proapoptotic activity of Bax by missense mutations found in gastrointestinal cancers. , 1999, Cancer research.
[4] C. la Vecchia,et al. Interaction between selected environmental factors and familial propensity for colon cancer. , 1999, European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation.
[5] Raymond L. White,et al. Regulation of β-Catenin Signaling by the B56 Subunit of Protein Phosphatase 2A , 1999 .
[6] Bandaru S. Reddy,et al. Role of dietary fiber in colon cancer: an overview. , 1999, The American journal of medicine.
[7] E. P. Kennedy,et al. Genetics of colorectal cancer. , 1998, Seminars in surgical oncology.
[8] T. Sugimura,et al. Genetic determinant and environmental carcinogens. , 1998, Mutation research.
[9] R. Bold,et al. Apoptosis, cancer and cancer therapy. , 1997, Surgical oncology.
[10] K. Kinzler,et al. Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC−/− Colon Carcinoma , 1997, Science.
[11] K. Kinzler,et al. Lessons from Hereditary Colorectal Cancer , 1996, Cell.
[12] K. Kinzler,et al. Apoptosis and APC in colorectal tumorigenesis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[13] C. Der,et al. Loss of oncogenic ras expression does not correlate with loss of tumorigenicity in human cells. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[14] M. Peifer. Regulating Cell Proliferation--As Easy as APC , 1996, Science.
[15] L. Ellis,et al. Molecular determinants in the biology of liver metastasis. , 1996, Surgical oncology clinics of North America.
[16] H. Lynch,et al. Overview of natural history, pathology, molecular genetics and management of HNPCC (Lynch syndrome) , 1996, International journal of cancer.
[17] John Calvin Reed. Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance. , 1995, Current opinion in oncology.
[18] E. Fearon. Molecular Genetics of Colorectal Cancer , 1995, Annals of the New York Academy of Sciences.
[19] T. Noda,et al. Subcellular localization of the APC protein: immunoelectron microscopic study of the association of the APC protein with catenin. , 1995, Oncogene.
[20] Y. Nakamura,et al. Genomic structure of human mismatch repair gene, hMLH1, and its mutation analysis in patients with hereditary non-polyposis colorectal cancer (HNPCC) , 1995, Human molecular genetics.
[21] V. Lazar,et al. Accumulation of multiple mutations in tumour suppressor genes during colorectal tumorigenesis in HNPCC patients. , 1994, Human molecular genetics.
[22] L. Ellis,et al. The implications of angiogenesis for the biology and therapy of cancer metastasis , 1994, Cell.
[23] L. Loeb. Microsatellite Instability: Marker of a Mutator Phenotype in Cancer , 1994 .
[24] K. Kinzler,et al. hMSH2 mutations in hereditary nonpolyposis colorectal cancer kindreds. , 1994, Cancer research.
[25] R. Fleischmann,et al. Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer , 1994, Nature.
[26] Z. F. Liu,et al. Allelic loss of chromosome 18q and prognosis in colorectal cancer. , 1994, The New England journal of medicine.
[27] D. Ward,et al. Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer , 1994, Nature.
[28] Robin J. Leach,et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer , 1993, Cell.
[29] N. Copeland,et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer , 1993, Cell.
[30] E. Kaplan,et al. K-ras mutations in putative preneoplastic lesions in human colon. , 1993, Journal of the National Cancer Institute.
[31] M. Hollstein,et al. Clinical implications of the p53 tumor-suppressor gene. , 1993, The New England journal of medicine.
[32] B. Zetter,et al. Adhesion molecules in tumor metastasis. , 1993, Seminars in cancer biology.
[33] G. Capellá,et al. Genetic heterogeneity of the c-K-ras locus in colorectal adenomas but not in adenocarcinomas. , 1993, Journal of the National Cancer Institute.
[34] L. Roncucci,et al. Identification of hereditary nonpolyposis colorectal cancer in the general population. The 6‐year experience of a population‐based registry , 1993, Cancer.
[35] K. Kinzler,et al. Clues to the pathogenesis of familial colorectal cancer. , 1993, Science.
[36] L. Feig. The many roads that lead to Ras. , 1993, Science.
[37] S. Shirasawa,et al. Altered growth of human colon cancer cell lines disrupted at activated Ki-ras. , 1993, Science.
[38] K. Kinzler,et al. The APC gene product in normal and tumor cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[39] Kathleen R. Cho,et al. Genetic alterations in the adenoma–carcinoma sequence , 1992, Cancer.
[40] J. Kere,et al. Evidence that the MCC-APC gene region in 5q21 is not the site for susceptibility to hereditary nonpolyposis colorectal carcinoma. , 1992, Cancer research.
[41] J. Fraumeni,et al. Follow-up study of twenty-four families with Li-Fraumeni syndrome. , 1991, Cancer research.
[42] Margaret Robertson,et al. Identification and characterization of the familial adenomatous polyposis coli gene , 1991, Cell.
[43] K. Kinzler,et al. Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. , 1991, Science.
[44] M. Oshimura,et al. Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 5 or 18 , 1991, Nature.
[45] B. Vogelstein,et al. p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. , 1990, Cancer research.
[46] B. Vogelstein,et al. Suppression of human colorectal carcinoma cell growth by wild-type p53. , 1990, Science.
[47] B. Vogelstein,et al. A genetic model for colorectal tumorigenesis , 1990, Cell.
[48] Kathleen R. Cho,et al. Identification of a chromosome 18q gene that is altered in colorectal cancers. , 1990, Science.
[49] H. J. Evans,et al. High frequency of APC loss in sporadic colorectal carcinoma due to breaks clustered in 5q21-22. , 1989, Oncogene.
[50] K. Sugio,et al. Loss of constitutional heterozygosity in colorectal tumors from patients with familial polyposis coli and those with nonpolyposis colorectal carcinoma. , 1989, Cancer research.
[51] A. Feinberg,et al. MULTIPLE GENETIC ALTERATIONS IN DISTAL AND PROXIMAL COLORECTAL CANCER , 1989, The Lancet.
[52] D. Ledbetter,et al. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. , 1989, Science.
[53] C. Marshall,et al. A study of ras gene mutations in colonic adenomas from familial polyposis coli patients. , 1988, Oncogene.
[54] T. Smyrk,et al. Hereditary nonpolyposis colorectal cancer--Lynch syndromes I and II. , 1988, Gastroenterology clinics of North America.
[55] Y. Nakamura,et al. Genetic alterations during colorectal-tumor development. , 1988, The New England journal of medicine.
[56] G. Bolis. Randomised comparison of cisplatin with Cyclophosphamide/Cisplatin and with Cyclophosphamide/Doxorubicin/Cisplatin in advanced ovarian cancer , 1988 .
[57] Y. Nakamura,et al. The gene for familial polyposis coli maps to the long arm of chromosome 5. , 1987, Science.
[58] J. Mecklin. Frequency of hereditary colorectal carcinoma. , 1987, Gastroenterology.
[59] W. Cavenee,et al. Genetics of cancer predisposition. , 1987, Cancer research.
[60] B. Vogelstein,et al. Clonal analysis of human colorectal tumors. , 1987, Science.
[61] I. Herskowitz. Functional inactivation of genes by dominant negative mutations , 1987, Nature.
[62] F. C. Lucibello,et al. Localization of the gene for familial adenomatous polyposis on chromosome 5 , 1987, Nature.
[63] A. Sandberg,et al. Gardner syndrome in a man with an interstitial deletion of 5q. , 1986, American journal of medical genetics.
[64] R. Elston,et al. Hereditary nonpolyposis colorectal cancer (lynch syndromes I and II). I. Clinical description of resource , 1985, Cancer.
[65] A. Knudson. Hereditary cancer, oncogenes, and antioncogenes. , 1985, Cancer research.
[66] D. Lane,et al. T antigen is bound to a host protein in SY40-transformed cells , 1979, Nature.
[67] Taylor Murray,et al. Cancer statistics, 1999 , 1999, CA: a cancer journal for clinicians.
[68] L. Aaltonen,et al. A novel approach to estimate the proportion of hereditary nonpolyposis colorectal cancer of total colorectal cancer burden. , 1994, Cancer detection and prevention.
[69] D. Wynford‐Thomas,et al. In vitro transformation of epithelial cells by ras oncogenes. , 1993, Epithelial cell biology.
[70] William E. Grizzle,et al. Detection of high incidence of K-ras oncogenes during human colon tumorigenesis , 1987, Nature.
[71] B. Vogelstein,et al. Prevalence of ras gene mutations in human colorectal cancers , 1987, Nature.