A temible complication of ischemic stroke: pulmonary embolism

Stroke is a leading cause of death and disability and is the third highest cause of death in the western world. Medical illness after ischemic stroke contribute substantially to poor stroke outcomes. The early in-hospital complications of stroke patients are mainly: pneumonia (hospital acquired pulmonary infection), increased intracranial pressure (neuroimaging evidence of cerebral edema or brain shift syndrome with clinical deterioration), urinary tract infection, intracerebral bleeding, recurrent stroke, epileptic seizures, thrombosis or pulmonary embolism. All these complications influence the patient’s outcomes and require diagnostic and therapeutic measures. Pulmonary embolism is a major contributor to in-hospital death after stroke. Although the rate of clinically overt pulmonary embolism after stroke has been estimated to be less than 1%, pulmonary emboli account for up to 50% of early deaths after stroke. In daily practice, the clinical burden of pulmonary embolism in patient with stroke is, however, underestimated since the clinical symptoms of stroke may obscure the recognition of this complication. The aim of this article is to describe the clinical and therapeutic aspects of pulmonary embolism as complication after stroke.

[1]  T. Corrah,et al.  Diagnosis and initial management of malaria. , 2017, British journal of hospital medicine.

[2]  A. Torbicki,et al.  Management of pulmonary embolism: recent evidence and the new European guidelines , 2014, European Respiratory Journal.

[3]  P. Moceri,et al.  Patent foramen ovale and stroke in intermediate-risk pulmonary embolism. , 2014, Chest.

[4]  C. Gaudio,et al.  Treatment of Acute Pulmonary Embolism: Update on Newer Pharmacologic and Interventional Strategies , 2014, BioMed research international.

[5]  Xingquan Zhao,et al.  Risk Assessment of Deep‐Vein Thrombosis After Acute Stroke: a Prospective Study Using Clinical Factors , 2014, CNS neuroscience & therapeutics.

[6]  P. Wells,et al.  Treatment of venous thromboembolism. , 2014, JAMA.

[7]  D. Kiely,et al.  Management dilemmas in acute pulmonary embolism , 2013, Thorax.

[8]  R. Swartz,et al.  Pulmonary Embolism in Ischemic Stroke: Clinical Presentation, Risk Factors, and Outcome , 2013, Journal of the American Heart Association.

[9]  P. Sandercock,et al.  Effectiveness of intermittent pneumatic compression in reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial , 2013, The Lancet.

[10]  M. Wintermark,et al.  Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association , 2013, Stroke.

[11]  R. Yusen,et al.  Venous Thromboembolism Risk in Ischemic Stroke Patients Receiving Extended-Duration Enoxaparin Prophylaxis: Results From the EXCLAIM Study , 2013, Stroke.

[12]  N. Wahlgren,et al.  Intravenous Alteplase in Ischemic Stroke Patients not Fully Adhering to the Current Drug License in Central and Eastern Europe , 2012, International journal of stroke : official journal of the International Stroke Society.

[13]  Elie A Akl,et al.  Prevention of VTE in Nonsurgical Patients Antithrombotic Therapy and Prevention of Thrombosis , 9 th ed : American College of Chest Physicians Evidence-Based Clinical Practice Guidelines , 2013 .

[14]  P. Prandoni,et al.  A risk assessment model for the identification of hospitalized medical patients at risk for venous thromboembolism: the Padua Prediction Score , 2010, Journal of thrombosis and haemostasis : JTH.

[15]  Piotr Pruszczyk,et al.  Guidelines on the Diagnosis and Management of Acute Pulmonary Embolism , 2008 .

[16]  H. Sostman,et al.  Clinical characteristics of patients with acute pulmonary embolism: data from PIOPED II. , 2007, The American journal of medicine.

[17]  S. Goldhaber,et al.  Acute pulmonary embolism: part II: treatment and prophylaxis. , 2006, Circulation.

[18]  M. Caldwell,et al.  American Heart Association: Council on Cardiovascular Nursing , 2004, The Journal of cardiovascular nursing.

[19]  Jeroen J. Bax,et al.  ESC Guidelines on the diagnosis and management of acute pulmonary embolism , 2014 .

[20]  C. S. Gray,et al.  Stroke and Transient Ischaemic Attack , 2009 .