DNA-microarray analysis of brain cancer: molecular classification for therapy

[1]  S. Horvath,et al.  Gene Expression Profiling of Gliomas Strongly Predicts Survival , 2004, Cancer Research.

[2]  G. Rao,et al.  Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice , 2004, Oncogene.

[3]  S. Gabriel,et al.  EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy , 2004, Science.

[4]  Patricia L. Harris,et al.  Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. , 2004, The New England journal of medicine.

[5]  Sridhar Ramaswamy,et al.  Translating cancer genomics into clinical oncology. , 2004, The New England journal of medicine.

[6]  Ash A. Alizadeh,et al.  Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes. , 2004, The New England journal of medicine.

[7]  Edison T Liu,et al.  Microarrays and clinical investigations. , 2004, The New England journal of medicine.

[8]  R. Tibshirani,et al.  Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia. , 2004, The New England journal of medicine.

[9]  R. Verhaak,et al.  Prognostically useful gene-expression profiles in acute myeloid leukemia. , 2004, The New England journal of medicine.

[10]  T. Ideker Systems biology 101—what you need to know , 2004, Nature Biotechnology.

[11]  T. Higashiyama,et al.  Classification of Human Breast Cancer Using Gene Expression Profiling as a Component of the Survival Predictor Algorithm , 2004, Clinical Cancer Research.

[12]  Rebecca A Betensky,et al.  Combining gene expression profiles and clinical parameters for risk stratification in medulloblastomas. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[13]  M. Rubin,et al.  Prostate Pathology of Genetically Engineered Mice: Definitions and Classification. The Consensus Report from the Bar Harbor Meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee , 2004, Cancer Research.

[14]  Amar Gajjar,et al.  Clinical, histopathologic, and molecular markers of prognosis: toward a new disease risk stratification system for medulloblastoma. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[15]  W. Gerald,et al.  Gene expression profiling predicts clinical outcome of prostate cancer. , 2004, The Journal of clinical investigation.

[16]  Todd R Golub,et al.  Gene expression–based high-throughput screening(GE-HTS) and application to leukemia differentiation , 2004, Nature Genetics.

[17]  A. Barabasi,et al.  Network biology: understanding the cell's functional organization , 2004, Nature Reviews Genetics.

[18]  R. Tibshirani,et al.  Gene expression profiling identifies clinically relevant subtypes of prostate cancer. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[19]  Ash A. Alizadeh,et al.  Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds , 2004, PLoS biology.

[20]  Jose J. Galvez,et al.  Validation: The New Challenge for Pathology , 2004, Toxicologic pathology.

[21]  S. Bergmann,et al.  Similarities and Differences in Genome-Wide Expression Data of Six Organisms , 2003, PLoS biology.

[22]  Eric P. Hoffman,et al.  The PEPR GeneChip data warehouse, and implementation of a dynamic time series query tool (SGQT) with graphical interface , 2004, Nucleic Acids Res..

[23]  Daniel H. Geschwind,et al.  Cancerous stem cells can arise from pediatric brain tumors , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[24]  W. Gerald,et al.  Value of Histopathology in Predicting Microsatellite Instability in Hereditary Nonpolyposis Colorectal Cancer and Sporadic Colorectal Cancer , 2003, The American journal of surgical pathology.

[25]  P. Shannon,et al.  Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.

[26]  F. Doetsch,et al.  The glial identity of neural stem cells , 2003, Nature Neuroscience.

[27]  Harvey R Herschman,et al.  Molecular Imaging: Looking at Problems, Seeing Solutions , 2003, Science.

[28]  Daniel Pinkel,et al.  Genomic microarrays in human genetic disease and cancer. , 2003, Human molecular genetics.

[29]  Eytan Domany,et al.  Classification of human astrocytic gliomas on the basis of gene expression: a correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes. , 2003, Cancer research.

[30]  Joshua M. Stuart,et al.  A Gene-Coexpression Network for Global Discovery of Conserved Genetic Modules , 2003, Science.

[31]  U. Alon Biological Networks: The Tinkerer as an Engineer , 2003, Science.

[32]  Steve Buckingham,et al.  Bioinformatics: Programmed for success , 2003, Nature.

[33]  Heather L. Miller,et al.  A molecular fingerprint for medulloblastoma. , 2003, Cancer research.

[34]  Alan Ruttenberg,et al.  Computational knowledge integration in biopharmaceutical research , 2003, Briefings Bioinform..

[35]  Paul S Mischel,et al.  Gene expression profiling identifies molecular subtypes of gliomas , 2003, Oncogene.

[36]  R. Tibshirani,et al.  Repeated observation of breast tumor subtypes in independent gene expression data sets , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[37]  Paul S Mischel,et al.  Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo. , 2003, Cancer research.

[38]  Robert J. Wechsler-Reya,et al.  Transcriptional profiling of the Sonic hedgehog response: A critical role for N-myc in proliferation of neuronal precursors , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[39]  G. Mills,et al.  Loss of PTEN/MMAC1/TEP in EGF receptor-expressing tumor cells counteracts the antitumor action of EGFR tyrosine kinase inhibitors , 2003, Oncogene.

[40]  Paul Cairns,et al.  Genome-wide genetic characterization of bladder cancer: a comparison of high-density single-nucleotide polymorphism arrays and PCR-based microsatellite analysis. , 2003, Cancer research.

[41]  G. Rao,et al.  c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice. , 2003, Neoplasia.

[42]  Tim Hui-Ming Huang,et al.  Triple analysis of the cancer epigenome: an integrated microarray system for assessing gene expression, DNA methylation, and histone acetylation. , 2003, Cancer research.

[43]  Paul S Mischel,et al.  Identification of molecular subtypes of glioblastoma by gene expression profiling , 2003, Oncogene.

[44]  D. Dressman,et al.  Overexpression of the EGFR/FKBP12/HIF-2alpha pathway identified in childhood astrocytomas by angiogenesis gene profiling. , 2003, Cancer research.

[45]  Emanuel F Petricoin,et al.  Protein microarrays: meeting analytical challenges for clinical applications. , 2003, Cancer cell.

[46]  T. Golub,et al.  Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. , 2003, Cancer research.

[47]  Paul S Mischel,et al.  Molecular Analysis of Glioblastoma: Pathway Profiling and Its Implications for Patient Therapy , 2003, Cancer biology & therapy.

[48]  M. Ringnér,et al.  Molecular classification of familial non-BRCA1/BRCA2 breast cancer , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[49]  David Botstein,et al.  Variation in gene expression patterns in follicular lymphoma and the response to rituximab , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[50]  David N Louis,et al.  Oligodendroglioma: Toward Molecular Definitions in Diagnostic Neuro‐Oncology , 2003, Journal of neuropathology and experimental neurology.

[51]  Paul S Mischel,et al.  Targeted Molecular Therapy of GBM , 2003, Brain pathology.

[52]  D. Covell,et al.  Mining the NCI screening database: explorations of agents involved in cell cycle regulation. , 2003, Progress in cell cycle research.

[53]  S. Elledge,et al.  Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease , 2003, Nature Genetics.

[54]  J. Downing,et al.  Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells , 2003, Nature Genetics.

[55]  D. Slonim From patterns to pathways: gene expression data analysis comes of age , 2002, Nature Genetics.

[56]  P. Mckinnon,et al.  DNA ligase IV suppresses medulloblastoma formation. , 2002, Cancer research.

[57]  Daniel H Turnbull,et al.  Induction of medulloblastomas in mice by sonic hedgehog, independent of Gli1. , 2002, Cancer research.

[58]  James M. Olson,et al.  Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade , 2002, Science.

[59]  Mark R Gilbert,et al.  Gene expression microarray analysis reveals YKL-40 to be a potential serum marker for malignant character in human glioma. , 2002, Cancer research.

[60]  H. Agrawal Extreme self-organization in networks constructed from gene expression data. , 2002, Physical review letters.

[61]  C. Sawyers,et al.  The phosphatidylinositol 3-Kinase–AKT pathway in human cancer , 2002, Nature Reviews Cancer.

[62]  L. Staudt,et al.  The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. , 2002, The New England journal of medicine.

[63]  C. Ball,et al.  Identification of genes periodically expressed in the human cell cycle and their expression in tumors. , 2002, Molecular biology of the cell.

[64]  D. Louis,et al.  Influence of unrecognized molecular heterogeneity on randomized clinical trials. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[65]  M. Berger,et al.  Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

[66]  David J. Anderson,et al.  The bHLH Transcription Factors OLIG2 and OLIG1 Couple Neuronal and Glial Subtype Specification , 2002, Cell.

[67]  Tao Sun,et al.  Common Developmental Requirement for Olig Function Indicates a Motor Neuron/Oligodendrocyte Connection , 2002, Cell.

[68]  T. Golub,et al.  DNA microarrays in clinical oncology. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[69]  R. DePinho,et al.  Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. , 2002, Cancer cell.

[70]  Xiang-Dong Fu,et al.  Profiling alternative splicing on fiber-optic arrays , 2002, Nature Biotechnology.

[71]  G. Reifenberger,et al.  The WHO Classification of Tumors of the Nervous System , 2002, Journal of neuropathology and experimental neurology.

[72]  C. Sawyers Disabling Abl-perspectives on Abl kinase regulation and cancer therapeutics. , 2002, Cancer cell.

[73]  B. Druker,et al.  Perspectives on the development of a molecularly targeted agent. , 2002, Cancer cell.

[74]  T. Poggio,et al.  Prediction of central nervous system embryonal tumour outcome based on gene expression , 2002, Nature.

[75]  L. Crosby,et al.  Toxicogenomics, Drug Discovery, and the Pathologist , 2002, Toxicologic pathology.

[76]  E. Lander,et al.  MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia , 2002, Nature Genetics.

[77]  Van,et al.  A gene-expression signature as a predictor of survival in breast cancer. , 2002, The New England journal of medicine.

[78]  C. Sotiriou,et al.  Gene expression profiles derived from fine needle aspiration correlate with response to systemic chemotherapy in breast cancer , 2002, Breast Cancer Research.

[79]  T. Poggio,et al.  Multiclass cancer diagnosis using tumor gene expression signatures , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[80]  L. Greene,et al.  Regulation of Neuronal Survival and Death by E2F-Dependent Gene Repression and Derepression , 2001, Neuron.

[81]  David E. Misek,et al.  Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis. , 2001, Cancer research.

[82]  J. Mesirov,et al.  Chemosensitivity prediction by transcriptional profiling , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[83]  R. Tibshirani,et al.  Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[84]  S. Dhanasekaran,et al.  Delineation of prognostic biomarkers in prostate cancer , 2001, Nature.

[85]  M. Scott,et al.  The developmental biology of brain tumors. , 2001, Annual review of neuroscience.

[86]  M. Kurrer,et al.  Gene expression profiling of low-grade diffuse astrocytomas by cDNA arrays. , 2000, Cancer research.

[87]  O. Kallioniemi,et al.  Identification of differentially expressed genes in human gliomas by DNA microarray and tissue chip techniques. , 2000, Cancer research.

[88]  A. Butte,et al.  Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[89]  R. Albert,et al.  The large-scale organization of metabolic networks , 2000, Nature.

[90]  T. Weissman,et al.  Identification of diverse nerve growth factor-regulated genes by serial analysis of gene expression (SAGE) profiling. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[91]  Eric S. Lander,et al.  Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays , 2000, Nature Biotechnology.

[92]  Christian A. Rees,et al.  Molecular portraits of human breast tumours , 2000, Nature.

[93]  Eric C. Holland,et al.  Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice , 2000, Nature Genetics.

[94]  D. Botstein,et al.  A gene expression database for the molecular pharmacology of cancer , 2000, Nature Genetics.

[95]  D. Botstein,et al.  Large-scale identification of secreted and membrane-associated gene products using DNA microarrays , 1999, Nature Genetics.

[96]  G. Segal Re: Brain and other central nervous system cancers: recent trends in incidence and mortality. , 2000, Journal of the National Cancer Institute.

[97]  J. Hopfield,et al.  From molecular to modular cell biology , 1999, Nature.

[98]  J. Mesirov,et al.  Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. , 1999, Science.

[99]  W. Yung,et al.  Reactivation of insulin-like growth factor binding protein 2 expression in glioblastoma multiforme: a revelation by parallel gene expression profiling. , 1999, Cancer research.

[100]  Linet,et al.  RESPONSE: Re: Brain and Other Central Nervous System Cancers: Recent Trends in Incidence and Mortality. , 1999, Journal of the National Cancer Institute.

[101]  Daniel A. Lim,et al.  Subventricular Zone Astrocytes Are Neural Stem Cells in the Adult Mammalian Brain , 1999, Cell.

[102]  S. Crest Programmed for success , 1997 .

[103]  P. Bailey,et al.  A classification of the tumors of the glioma group on a histogenetic basis with a correlated study of prognosis , 1970 .