Lipopolysaccharide alters the blood–brain barrier transport of amyloid β protein: A mechanism for inflammation in the progression of Alzheimer’s disease

[1]  S. M. Robinson,et al.  Effects of triglycerides, obesity, and starvation on ghrelin transport across the blood–brain barrier , 2008, Peptides.

[2]  A. Granholm,et al.  Endotoxin induces a delayed loss of TH-IR neurons in substantia nigra and motor behavioral deficits. , 2008, Neurotoxicology.

[3]  W. Banks,et al.  Starvation and triglycerides reverse the obesity-induced impairment of insulin transport at the blood-brain barrier. , 2008, Endocrinology.

[4]  D. Strickland,et al.  LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies. , 2008, Physiological reviews.

[5]  R. Deane,et al.  The role of the cell surface LRP and soluble LRP in blood-brain barrier Abeta clearance in Alzheimer's disease. , 2008, Current pharmaceutical design.

[6]  W. Banks,et al.  Nitric oxide isoenzymes regulate lipopolysaccharide-enhanced insulin transport across the blood-brain barrier. , 2008, Endocrinology.

[7]  J. Nutt,et al.  Strategies to advance translational research into brain barriers , 2008, The Lancet Neurology.

[8]  Michael S. Wolfe,et al.  Presenilin: Running with Scissors in the Membrane , 2007, Cell.

[9]  D. Holtzman,et al.  Transport Pathways for Clearance of Human Alzheimer's Amyloid β-Peptide and Apolipoproteins E and J in the Mouse Central Nervous System , 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[10]  F. Crews,et al.  Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration , 2007, Glia.

[11]  J. Silverman,et al.  Cardiovascular risk factors for Alzheimer's disease. , 2007, The American journal of geriatric cardiology.

[12]  W. Banks,et al.  Release of cytokines by brain endothelial cells: A polarized response to lipopolysaccharide , 2006, Brain, Behavior, and Immunity.

[13]  D. Praticò,et al.  Novel therapeutic opportunities for Alzheimer's disease: focus on nonsteroidal anti‐inflammatory drugs , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[14]  D. Butterfield,et al.  Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Abeta region of amyloid precursor protein. , 2005, Brain research. Molecular brain research.

[15]  P Couvreur,et al.  Puromycin‐based purification of rat brain capillary endothelial cell cultures. Effect on the expression of blood–brain barrier‐specific properties , 2005, Journal of neurochemistry.

[16]  W. Banks,et al.  Effect of lipopolysaccharide on the transport of pituitary adenylate cyclase activating polypeptide across the blood–brain barrier , 2005, Experimental Neurology.

[17]  D. Butterfield,et al.  Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain , 2004, Neuroscience.

[18]  R. Deane,et al.  RAGE (Yin) Versus LRP (Yang) Balance Regulates Alzheimer Amyloid &bgr;-Peptide Clearance Through Transport Across the Blood–Brain Barrier , 2004, Stroke.

[19]  R. Deane,et al.  Method for measurement of the blood–brain barrier permeability in the perfused mouse brain: application to amyloid-β peptide in wild type and Alzheimer’s Tg2576 mice , 2004, Journal of Neuroscience Methods.

[20]  D. Butterfield,et al.  Antisense directed at the Aβ region of APP decreases brain oxidative markers in aged senescence accelerated mice , 2004, Brain Research.

[21]  Peter J. Lenting,et al.  LRP/Amyloid β-Peptide Interaction Mediates Differential Brain Efflux of Aβ Isoforms , 2004, Neuron.

[22]  W. Banks,et al.  Effects of lipopolysaccharide on leptin transport across the blood–brain barrier , 2004, Brain Research.

[23]  B. Zlokovic.  Clearing amyloid through the blood–brain barrier , 2004, Journal of neurochemistry.

[24]  S. M. Robinson,et al.  Triglycerides induce leptin resistance at the blood-brain barrier. , 2004, Diabetes.

[25]  S. M. Robinson,et al.  Efflux of human and mouse amyloid β proteins 1–40 and 1–42 from brain: impairment in a mouse model of alzheimer's disease , 2003, Neuroscience.

[26]  D. Borchelt,et al.  Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid β peptide in APPswe transgenic mice , 2003, Neurobiology of Disease.

[27]  Ann Marie Schmidt,et al.  RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain , 2003, Nature Medicine.

[28]  D. Butterfield,et al.  The antioxidants α‐lipoic acid and N‐acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice , 2003, Journal of neurochemistry.

[29]  J. Hardy,et al.  The Amyloid Hypothesis of Alzheimer ’ s Disease : Progress and Problems on the Road to Therapeutics , 2009 .

[30]  V. Perry,et al.  Peripheral infection evokes exaggerated sickness behaviour in pre-clinical murine prion disease , 2002, Neuroscience.

[31]  W. Banks,et al.  Alzheimer’s disease through the eye of a mouse Acceptance lecture for the 2001 Gayle A. Olson and Richard D. Olson prize , 2002, Peptides.

[32]  D. Butterfield,et al.  Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide. , 2001, Trends in molecular medicine.

[33]  A. Dunn,et al.  Behavioral Effects of Cytokines , 2001, Brain, Behavior, and Immunity.

[34]  M. Croft,et al.  Signaling through OX40 (CD134) breaks peripheral T-cell tolerance , 2001, Nature Medicine.

[35]  W. Banks,et al.  Effect of LPS on the permeability of the blood–brain barrier to insulin , 2001, Brain Research.

[36]  D. Holtzman,et al.  Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. , 2000, The Journal of clinical investigation.

[37]  W. Banks,et al.  Partial saturation and regional variation in the blood-to-brain transport of leptin in normal weight mice. , 2000, American journal of physiology. Endocrinology and metabolism.

[38]  N. Inestrosa,et al.  Expression of α2‐macroglobulin receptor/low density lipoprotein receptor‐related protein (LRP) in rat microglial cells , 2000, Journal of neuroscience research.

[39]  W. Banks,et al.  Adsorptive Endocytosis of HIV-1gp120 by Blood–Brain Barrier Is Enhanced by Lipopolysaccharide , 1999, Experimental Neurology.

[40]  K. Nakadate,et al.  Brain Endothelial Cells Express Cyclooxygenase-2 during Lipopolysaccharide-Induced Fever: Light and Electron Microscopic Immunocytochemical Studies , 1998, The Journal of Neuroscience.

[41]  W. Banks,et al.  The putative blood-brain barrier transporter for the beta-amyloid binding protein apolipoprotein j is saturated at physiological concentrations. , 1997, Life sciences.

[42]  B. Zlokovic.  Cerebrovascular transport of Alzheimer's amyloid beta and apolipoproteins J and E: possible anti-amyloidogenic role of the blood-brain barrier. , 1996, Life Science.

[43]  L. Mucke,et al.  Comparison of Neurodegenerative Pathology in Transgenic Mice Overexpressing V717F β-Amyloid Precursor Protein and Alzheimer’s Disease , 1996, The Journal of Neuroscience.

[44]  C. Patlak,et al.  Fate of Cerebrospinal Fluid‐Borne Amyloid β‐Peptide: Rapid Clearance into Blood and Appreciable Accumulation by Cerebral Arteries , 1996, Journal of neurochemistry.

[45]  E. Matsubara,et al.  Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[46]  B. Zlokovic,et al.  Blood-brain barrier uptake of the 40 and 42 amino acid sequences of circulating Alzheimer's amyloid β in guinea pigs , 1996, Neuroscience Letters.

[47]  A. Moor,et al.  Lymphocyte adhesion to brain capillary endothelial cells in vitro , 1994, Journal of Neuroimmunology.

[48]  P. Quesenberry,et al.  Regulation of macrophage alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein by lipopolysaccharide and interferon-gamma. , 1993, The Journal of clinical investigation.

[49]  J. Tillement,et al.  Drug Transfer Across the Blood‐Brain Barrier: Correlation Between In Vitro and In Vivo Models , 1992 .

[50]  L. Drewes,et al.  Cultured human and canine endothelial cells from brain microvessels , 1988, Brain Research Bulletin.

[51]  W. Banks,et al.  Differential effect of aluminum on the blood-brain barrier transport of peptides, technetium and albumin. , 1988, The Journal of pharmacology and experimental therapeutics.

[52]  S. Rapoport,et al.  Kinetics of Neutral Amino Acid Transport Across the Blood‐Brain Barrier , 1987, Journal of neurochemistry.

[53]  Ronald G. Blasberg,et al.  Transport of α-Aminoisobutyric Acid across Brain Capillary and Cellular Membranes , 1983 .

[54]  C S Patlak,et al.  Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data , 1983, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[55]  M. Ashburner,et al.  Drosophila: the genetics of two major larval proteins , 1978, Cell.

[56]  S. M. Robinson,et al.  Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-beta protein, and impairs cognition. , 2009, Journal of Alzheimer's disease : JAD.

[57]  F. Joó,et al.  Production of pure primary rat cerebral endothelial cell culture: a comparison of different methods. , 1997, Neurobiology.

[58]  D. Selkoe,et al.  Passage of human amyloid β-protein 1–40 across the murine blood-brain barrier , 1994 .

[59]  C. Eastman,et al.  Ontogeny of insulin binding in different regions of the rat brain. , 1990, Developmental neuroscience.

[60]  W. Banks,et al.  Quantifying carrier-mediated transport of peptides from the brain to the blood. , 1989, Methods in enzymology.

[61]  S. Colowick,et al.  Methods in Enzymology , Vol , 1966 .