Intelligent biology and medicine in 2015: advancing interdisciplinary education, collaboration, and data science

We summarize the 2015 International Conference on Intelligent Biology and Medicine (ICIBM 2015) and the editorial report of the supplement to BMC Genomics. The supplement includes 20 research articles selected from the manuscripts submitted to ICIBM 2015. The conference was held on November 13–15, 2015 at Indianapolis, Indiana, USA. It included eight scientific sessions, three tutorials, four keynote presentations, three highlight talks, and a poster session that covered current research in bioinformatics, systems biology, computational biology, biotechnologies, and computational medicine.

[1]  Yufei Huang,et al.  Detection of high variability in gene expression from single-cell RNA-seq profiling , 2016, BMC Genomics.

[2]  Guanglong Jiang,et al.  Comprehensive comparison of molecular portraits between cell lines and tumors in breast cancer , 2016, BMC Genomics.

[3]  Jie Zhang,et al.  A matrix rank based concordance index for evaluating and detecting conditional specific co-expressed gene modules , 2016, BMC Genomics.

[4]  Weixing Feng,et al.  Identification of rifampin-regulated functional modules and related microRNAs in human hepatocytes based on the protein interaction network , 2016, BMC Genomics.

[5]  Yunlong Liu,et al.  Statistical modeling for sensitive detection of low-frequency single nucleotide variants , 2016, BMC Genomics.

[6]  Yufei Huang,et al.  A hierarchical model for clustering m6A methylation peaks in MeRIP-seq data , 2016, BMC Genomics.

[7]  Timothy P. L. Smith,et al.  Whole genomic sequence analysis of Bacillus infantis: defining the genetic blueprint of strain NRRL B-14911, an emerging cardiopathogenic microbe , 2016, BMC Genomics.

[8]  Sarath Chandra Janga,et al.  Benchmarking of de novo assembly algorithms for Nanopore data reveals optimal performance of OLC approaches , 2016, BMC Genomics.

[9]  Rong Xu,et al.  Towards precision medicine-based therapies for glioblastoma: interrogating human disease genomics and mouse phenotypes , 2016, BMC Genomics.

[10]  A. Dunker,et al.  Lipopolysaccharide treatment induces genome-wide pre-mRNA splicing pattern changes in mouse bone marrow stromal stem cells , 2016, BMC Genomics.

[11]  Jie Zhang,et al.  Integrative analysis of somatic mutations and transcriptomic data to functionally stratify breast cancer patients , 2016, BMC Genomics.

[12]  Lizhong Ding,et al.  Read-Split-Run: an improved bioinformatics pipeline for identification of genome-wide non-canonical spliced regions using RNA-Seq data , 2016, BMC Genomics.

[13]  J. Chen,et al.  A method for identifying discriminative isoform-specific peptides for clinical proteomics application , 2016, BMC Genomics.

[14]  QuanQiu Wang,et al.  A genomics-based systems approach towards drug repositioning for rheumatoid arthritis , 2016, BMC Genomics.

[15]  Zhongming Zhao,et al.  Concordance of copy number loss and down-regulation of tumor suppressor genes: a pan-cancer study , 2016, BMC Genomics.

[16]  Weixing Feng,et al.  Improving alignment accuracy on homopolymer regions for semiconductor-based sequencing technologies , 2016, BMC Genomics.

[17]  E. Serpedin,et al.  CrossLink: a novel method for cross-condition classification of cancer subtypes , 2016, BMC Genomics.

[18]  Wenguang Zhang,et al.  Whole blood transcriptional profiling comparison between different milk yield of Chinese Holstein cows using RNA-seq data , 2016, BMC Genomics.

[19]  Zhongming Zhao,et al.  An integrative genomics approach for identifying novel functional consequences of PBRM1 truncated mutations in clear cell renal cell carcinoma (ccRCC) , 2016, BMC genomics.

[20]  Yufeng Wang,et al.  Genomic data mining reveals a rich repertoire of transport proteins in Streptomyces , 2016, BMC Genomics.