RANKL expression specifically observed in vivo promotes epithelial mesenchymal transition and tumor progression.
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[1] Robert A. Weinberg,et al. The basics of epithelial-mesenchymal transition. , 2009, The Journal of clinical investigation.
[2] D. Tarin,et al. Integrin αvβ3/c-src “Oncogenic Unit” Promotes Anchorage-independence and Tumor Progression , 2009, Nature Medicine.
[3] Raghu Kalluri,et al. The basics of epithelial-mesenchymal transition. , 2009, The Journal of clinical investigation.
[4] J. Pollard,et al. Microenvironmental regulation of metastasis , 2009, Nature Reviews Cancer.
[5] Sendurai A Mani,et al. The Epithelial-to-Mesenchymal Transition and Cancer Stem Cells: A Coalition Against Cancer Therapies , 2009, Journal of Mammary Gland Biology and Neoplasia.
[6] Lesley A. Mathews,et al. Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature , 2009, Clinical & Experimental Metastasis.
[7] Y. Ohba,et al. Integral role of transcription factor 8 in the negative regulation of tumor angiogenesis. , 2009, Cancer research.
[8] Y. Ohba,et al. Transcription factor 8 activates R-Ras to regulate angiogenesis. , 2009, Biochemical and biophysical research communications.
[9] J. Penninger,et al. RANK/RANKL: Regulators of Immune Responses and Bone Physiology , 2008, Annals of the New York Academy of Sciences.
[10] A. Puisieux,et al. Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition , 2008, PloS one.
[11] J. Massagué,et al. TGFβ in Cancer , 2008, Cell.
[12] Robert A. Weinberg,et al. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. , 2008, Developmental cell.
[13] Wenjun Guo,et al. The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells , 2008, Cell.
[14] Y. Ohba,et al. PTHrP promotes malignancy of human oral cancer cell downstream of the EGFR signaling. , 2008, Biochemical and biophysical research communications.
[15] S. Choi,et al. Molecular Pathogenesis of Oral Squamous Cell Carcinoma: Implications for Therapy , 2008, Journal of dental research.
[16] C. Van Waes,et al. Role of activated nuclear factor‐κB in the pathogenesis and therapy of squamous cell carcinoma of the head and neck , 2007, Head & neck.
[17] J. Grandis,et al. NF-κB Gene Signatures and p53 Mutations in Head and Neck Squamous Cell Carcinoma , 2007, Clinical Cancer Research.
[18] John M. Wright,et al. Signal Transduction Pathways Involved in Epithelial-Mesenchymal Transition in Oral Cancer Compared with Other Cancers , 2007, Cells Tissues Organs.
[19] N. Takano,et al. Establishment of a murine model of bone invasion by oral squamous cell carcinoma. , 2007, Oral oncology.
[20] M. Sporn,et al. The tumour microenvironment as a target for chemoprevention , 2007, Nature Reviews Cancer.
[21] H. Yoshida,et al. Epithelial-mesenchymal transition induced by the stromal cell-derived factor-1/CXCR4 system in oral squamous cell carcinoma cells. , 2006, International journal of oncology.
[22] A. G. Herreros,et al. Snail-dependent and -independent Epithelial-Mesenchymal Transition in Oral Squamous Carcinoma Cells , 2006, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[23] G. Weinstein,et al. Identification of a Gene Signature for Rapid Screening of Oral Squamous Cell Carcinoma , 2006, Clinical Cancer Research.
[24] B. Wollenberg,et al. Role of cytokines in head and neck squamous cell carcinoma , 2006, Expert review of anticancer therapy.
[25] Robert A. Weinberg,et al. Stromal Fibroblasts in Cancer: A Novel Tumor-Promoting Cell Type , 2006, Cell cycle.
[26] G. Ogden,et al. Incidence of oral and oropharyngeal cancer in United Kingdom (1990-1999) -- recent trends and regional variation. , 2006, Oral oncology.
[27] Y. Shintani,et al. Phosphoinositide-3 kinase-Rac1-c-Jun NH2-terminal kinase signaling mediates collagen I-induced cell scattering and up-regulation of N-cadherin expression in mouse mammary epithelial cells. , 2006, Molecular biology of the cell.
[28] Lisa M. Ebert,et al. Directions in the immune targeting of cancer: Lessons learned from the cancer‐testis Ag NY‐ESO‐1 , 2006, Immunology and cell biology.
[29] A. Suri. Cancer testis antigens – their importance in immunotherapy and in the early detection of cancer , 2006, Expert opinion on biological therapy.
[30] J. Thiery,et al. Complex networks orchestrate epithelial–mesenchymal transitions , 2006, Nature Reviews Molecular Cell Biology.
[31] K. Verschueren,et al. Involvement of Ets-1 transcription factor in inducing matrix metalloproteinase-2 expression by epithelial-mesenchymal transition in human squamous carcinoma cells. , 2006, International journal of oncology.
[32] G. Berx,et al. The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program. , 2005, Cancer research.
[33] J. Joyce,et al. Therapeutic Targeting of the Tumor Microenvironment. , 2021, Cancer discovery.
[34] S. Hashimoto,et al. Effect of YM529 on a Model of Mandibular Invasion by Oral Squamous Cell Carcinoma in Mice , 2005, Clinical Cancer Research.
[35] B. Schmidt,et al. Tongue and tonsil carcinoma , 2005, Cancer.
[36] H. Saya,et al. Mechanism and biological significance of CD44 cleavage , 2004, Cancer science.
[37] A. Popovtzer,et al. Squamous Cell Carcinoma of the Oral Tongue in Young Patients , 2004, The Laryngoscope.
[38] G. Roodman. Mechanisms of bone metastasis. , 2004, Discovery medicine.
[39] N. Johnson,et al. An analysis of risk factors for oral cancer in young people: a case-control study. , 2004, Oral oncology.
[40] P. Gaffney,et al. Identification of a Gene Expression Signature Associated with Recurrent Disease in Squamous Cell Carcinoma of the Head and Neck , 2004, Cancer Research.
[41] Jean Paul Thiery,et al. Epithelial-mesenchymal transitions in development and pathologies. , 2003, Current opinion in cell biology.
[42] M. Maio,et al. Epigenetic targets for immune intervention in human malignancies , 2003, Oncogene.
[43] J. Shah,et al. Cyclooxygenase‐2: A novel molecular target for the prevention and treatment of head and neck cancer , 2002, Head & neck.
[44] G. Mundy. Metastasis: Metastasis to bone: causes, consequences and therapeutic opportunities , 2002, Nature Reviews Cancer.
[45] J. Thiery. Epithelial–mesenchymal transitions in tumour progression , 2002, Nature Reviews Cancer.
[46] Y. M. Lee,et al. TNF-related Activation-induced Cytokine (TRANCE) Induces Angiogenesis through the Activation of Src and Phospholipase C (PLC) in Human Endothelial Cells* , 2002, The Journal of Biological Chemistry.
[47] P. Reichart,et al. Identification of risk groups for oral precancer and cancer and preventive measures , 2001, Clinical Oral Investigations.
[48] Elise C. Kohn,et al. The microenvironment of the tumour–host interface , 2001, Nature.
[49] J. Myers,et al. Cancer of the oral cavity. , 2000, Current problems in surgery.
[50] A. G. Herreros,et al. The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells , 2000, Nature Cell Biology.
[51] Francisco Portillo,et al. The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression , 2000, Nature Cell Biology.
[52] R. Todd,et al. Epidermal growth factor receptor (EGFR) biology and human oral cancer. , 1999, Histology and histopathology.
[53] N. Udagawa,et al. A new member of tumor necrosis factor ligand family, ODF/OPGL/TRANCE/RANKL, regulates osteoclast differentiation and function. , 1999, Biochemical and biophysical research communications.
[54] D. Lacey,et al. Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation , 1998, Cell.
[55] K Yano,et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[56] A. Israël,et al. IκB proteins: structure, function and regulation , 1997 .
[57] S. Haskill,et al. Integrin-mediated Tyrosine Phosphorylation and Cytokine Message Induction in Monocytic Cells , 1995, The Journal of Biological Chemistry.
[58] C. Ostberg,et al. Fibronectin attachment activates the NF-kappa B p50/p65 heterodimer in fibroblasts and smooth muscle cells. , 1994, The Journal of biological chemistry.
[59] C. Rosen,et al. Antisense oligonucleotides to the p65 subunit of NF-kappa B block CD11b expression and alter adhesion properties of differentiated HL-60 granulocytes , 1993 .
[60] T. Coleman,et al. Evidence for differential functions of the p50 and p65 subunits of NF-kappa B with a cell adhesion model , 1993, Molecular and cellular biology.
[61] Yamamura Ken-ichi,et al. Efficient selection for high-expression transfectants with a novel eukaryotic vector , 1991 .
[62] H. Niwa,et al. Efficient selection for high-expression transfectants with a novel eukaryotic vector. , 1991, Gene.
[63] L. Orci,et al. Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors , 1991, Cell.
[64] H. Hiratsuka,et al. Mode of invasion, bleomycin sensitivity, and clinical course in squamous cell carcinoma of the oral cavity , 1983, Cancer.
[65] G. Fletcher,et al. Cancer of the oral cavity , 1970 .
[66] Izhak Haviv,et al. Co-evolution of tumor cells and their microenvironment. , 2009, Trends in genetics : TIG.
[67] Josef Gotzmann,et al. Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis. , 2004, Mutation research.
[68] P. Herrlich,et al. CD44: From adhesion molecules to signalling regulators , 2003, Nature Reviews Molecular Cell Biology.
[69] N. Kamata,et al. Reverse correlation of E-cadherin and snail expression in oral squamous cell carcinoma cells in vitro. , 2001, Oral oncology.
[70] A. Israël,et al. I kappa B proteins: structure, function and regulation. , 1997, Seminars in cancer biology.
[71] E. Jimi,et al. Role of 1 alpha,25-dihydroxyvitamin D3 in osteoclast differentiation and function. , 1997, Methods in enzymology.
[72] E. Hay. An overview of epithelio-mesenchymal transformation. , 1995, Acta anatomica.
[73] J. MontalvoScull. Incidence of oral and oropharyngeal cancer , 1978 .