Systemic lupus erythematosus is not genetically linked to the beta chain of the T cell receptor.

The genomic DNA polymorphism of the beta chain of the T cell receptor was examined. The restriction fragment length polymorphism distribution was similar in systemic lupus erythematosus patients, their relatives, and normal controls. Our observations suggest that these genes are not coinherited with genes responsible for systemic lupus erythematosus.

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