Virtual Tools for the Evaluation of Breast Imaging: State-of-the Science and Future Directions

The beginning of this century saw the development of simulation methods for the evaluation of breast imaging, motivated by the limitations of conventional clinical trials. This has led to the formation of AAPM Task Group on Virtual Tools for the Validation of 3D/4D X-ray Breast Imaging Systems TG234, gathering researchers from academia, industry, and government, interested in the development, testing, and adoption of these tools. TG234 is currently finalizing its report. The report has been designed as an experiential guide through the steps of simulating breast anatomy, image acquisition, image interpretation, and analysis. TG234 activities include disseminating the idea of virtual clinical trials through numerous focused conference sessions and AAPM annual meeting symposia. This paper reflects our desire to initiate wider discussion about the future directions in the development of virtual tools for the design and evaluation of novel breast imaging systems.