Anti-inflammatory effects of spermidine in lipopolysaccharide-stimulated BV2 microglial cells

[1]  J. Pezzuto,et al.  NFκB: a promising target for natural products in cancer chemoprevention , 2010, Phytotherapy research : PTR.

[2]  M. Schwartz,et al.  Systemic inflammatory cells fight off neurodegenerative disease , 2010, Nature Reviews Neurology.

[3]  T. Kilpatrick,et al.  Role of Cytokines as Mediators and Regulators of Microglial Activity in Inflammatory Demyelination of the CNS , 2010, NeuroMolecular Medicine.

[4]  D. Baker,et al.  Inflammation in neurodegenerative diseases , 2010, Immunology.

[5]  Frank Sinner,et al.  Induction of autophagy by spermidine promotes longevity , 2009, Nature Cell Biology.

[6]  Makoto Hashimoto,et al.  Possible roles of microglial cells for neurotoxicity in clinical neurodegenerative diseases and experimental animal models. , 2009, Inflammation & allergy drug targets.

[7]  T. Tennikova,et al.  Synthetic polycation: polynucleotide interactions determined using liquid chromatography with short monolithic columns. , 2009, Journal of Separation Science.

[8]  Marina A. Lynch,et al.  The Multifaceted Profile of Activated Microglia , 2009, Molecular Neurobiology.

[9]  R. McManus,et al.  NF-κB regulation: the nuclear response , 2009, Journal of cellular and molecular medicine.

[10]  P. Gasque,et al.  The Multiple Roles of the Innate Immune System in the Regulation of Apoptosis and Inflammation in the Brain , 2009, Journal of neuropathology and experimental neurology.

[11]  Shin-Young Park,et al.  Effect of sildenafil citrate on interleukin-1β-induced nitric oxide synthesis and iNOS expression in SW982 cells , 2008, Experimental & Molecular Medicine.

[12]  D. Fitzgerald,et al.  Role of the innate immune system in autoimmune inflammatory demyelination. , 2008, Current medicinal chemistry.

[13]  W. Yeh,et al.  LPS/TLR4 signal transduction pathway. , 2008, Cytokine.

[14]  Seung-Up Kim,et al.  Activation of nicotinic acetylcholine receptor prevents the production of reactive oxygen species in fibrillar β amyloid peptide (1-42)-stimulated microglia , 2008, Experimental & Molecular Medicine.

[15]  Zhiwei Wang,et al.  NF-κB Signaling Pathway and Its Therapeutic Implications in Human Diseases , 2008, International reviews of immunology.

[16]  N. Flamand,et al.  Characterization of prostaglandin E2 generation through the cyclooxygenase (COX)-2 pathway in human neutrophils. , 2007, Biochimica et biophysica acta.

[17]  C. Dong,et al.  Regulatory mechanisms of mitogen-activated kinase signaling , 2007, Cellular and Molecular Life Sciences.

[18]  S. Rivest,et al.  Neuroprotective role of the innate immune system by microglia , 2007, Neuroscience.

[19]  L. Alhonen,et al.  Oxidative stress and inflammation in the pathogenesis of activated polyamine catabolism-induced acute pancreatitis , 2007, Amino Acids.

[20]  A. C. Hunter.  Molecular hurdles in polyfectin design and mechanistic background to polycation induced cytotoxicity. , 2006, Advanced drug delivery reviews.

[21]  N. Nam.  Naturally occurring NF-kappaB inhibitors. , 2006, Mini reviews in medicinal chemistry.

[22]  T. Möller,et al.  Microglia Biology in Health and Disease , 2006, Journal of Neuroimmune Pharmacology.

[23]  I. Kang,et al.  Activation of adenosine A3 receptor suppresses lipopolysaccharide-induced TNF-α production through inhibition of PI 3-kinase/Akt and NF-κB activation in murine BV2 microglial cells , 2006, Neuroscience Letters.

[24]  Gang Wang,et al.  Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity , 2006, Nature Medicine.

[25]  U. Bachrach.  Naturally occurring polyamines: interaction with macromolecules. , 2005, Current protein & peptide science.

[26]  R. Banati,et al.  [Microglia--biology and relevance to disease]. , 2005, Ugeskrift for læger.

[27]  L. Minghetti.  Cyclooxygenase‐2 (COX‐2) in Inflammatory and Degenerative Brain Diseases , 2004, Journal of neuropathology and experimental neurology.

[28]  L. J. Eldik,et al.  Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1β production , 2004, Neurobiology of Aging.

[29]  M. Giovannini,et al.  Experimental brain inflammation and neurodegeneration as model of Alzheimer's disease: protective effects of selective COX-2 inhibitors. , 2003, International journal of immunopathology and pharmacology.

[30]  P. Lin,et al.  The biological activities of new polyamine derivatives as potential therapeutic agents. , 2003, Biochemical Society Transactions.

[31]  T. Thomas,et al.  Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications , 2001, Cellular and Molecular Life Sciences CMLS.

[32]  M. Caivano.  Role of MAP kinase cascades in inducing arginine transporters and nitric oxide synthetase in RAW264 macrophages , 1998, FEBS letters.

[33]  K. Igarashi,et al.  Polyamine lowered the hepatic lipid peroxide level in rats. , 1988, Research communications in chemical pathology and pharmacology.

[34]  K. Igarashi,et al.  Possible mechanism of inhibition by polyamines of lipid peroxidation in rat liver microsomes. , 1981, Research communications in chemical pathology and pharmacology.

[35]  K. Igarashi,et al.  Inhibition by polyamines of lipid peroxide formation in rat liver microsomes. , 1979, Biochemical and biophysical research communications.

[36]  Younghee Lee,et al.  Protection of burn-induced skin injuries by the flavonoid kaempferol. , 2010, BMB reports.

[37]  R. Maccioni,et al.  Neuroinflammation: implications for the pathogenesis and molecular diagnosis of Alzheimer's disease. , 2008, Archives of medical research.

[38]  M. Sabater-Molina,et al.  Biological significance of dietary polyamines. , 2007, Nutrition.

[39]  Kazuhide Inoue.  The function of microglia through purinergic receptors: neuropathic pain and cytokine release. , 2006, Pharmacology & therapeutics.

[40]  A. Szuba,et al.  The role of chemokines in human cardiovascular pathology: enhanced biological insights. , 2002, Atherosclerosis.

[41]  S. Murphy.  Production of nitric oxide by glial cells: Regulation and potential roles in the CNS , 2000, Glia.