Blockade of the Tumor Necrosis Factor-Related Apoptosis Inducing Ligand Death Receptor DR5 Prevents β-Amyloid Neurotoxicity
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M. Memo | P. Spano | D. Uberti | L. Benussi | R. Ghidoni | M. Pizzi | F. Facchetti | M. Benarese | I. Sarnico | G. Binetti | G. Ferrari-Toninelli | S. Bonini | G. Ferrari‐Toninelli
[1] M. Naoi,et al. Overexpression of amyloid precursor protein induces susceptibility to oxidative stress in human neuroblastoma SH-SY5Y cells , 2006, Journal of Neural Transmission.
[2] M. Coletta,et al. Aβ(31–35) peptide induce apoptosis in PC 12 cells: Contrast with Aβ(25–35) peptide and examination of underlying mechanisms , 2005, Neurochemistry International.
[3] G. Dawson,et al. Novel aspects of accumulation dynamics and Aβ composition in transgenic models of AD , 2004, Neurobiology of Aging.
[4] R. Reiter,et al. Kinetics of the neuroinflammation-oxidative stress correlation in rat brain following the injection of fibrillar amyloid-β onto the hippocampus in vivo , 2004, Journal of Neuroimmunology.
[5] M. Memo,et al. TRAIL is expressed in the brain cells of Alzheimer's disease patients , 2004, Neuroreport.
[6] Jialin Zheng,et al. TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia , 2004, Journal of Neuroimmunology.
[7] T. Pozzan,et al. The presenilin 2 M239I mutation associated with familial Alzheimer's disease reduces Ca2+ release from intracellular stores , 2004, Neurobiology of Disease.
[8] F. Heppner,et al. Current Concepts and Future Prospects for Alzheimer Disease Vaccines , 2004, Alzheimer disease and associated disorders.
[9] P. Secchiero,et al. Tumour necrosis factor‐related apoptosis‐inducing ligand sequentially activates pro‐survival and pro‐apoptotic pathways in SK‐N‐MC neuronal cells , 2003, Journal of neurochemistry.
[10] M. Tabaton,et al. Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis. , 2003, Free radical biology & medicine.
[11] Mamoru Ito,et al. Tumor necrosis factor-related apoptosis-inducing ligand induces neuronal death in a murine model of HIV central nervous system infection , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[12] Q. Peng,et al. Pycnogenol® protects neurons from amyloid-β peptide-induced apoptosis , 2002 .
[13] R. Mohs,et al. Consortium to establish a registry for Alzheimer's disease (CERAD) clinical and neuropsychological assessment of Alzheimer's disease. , 2002, Psychopharmacology bulletin.
[14] I. Bechmann,et al. Lack of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand But Presence of Its Receptors in the Human Brain , 2002, The Journal of Neuroscience.
[15] W Pieter Medendorp,et al. Rotational Remapping in Human Spatial Memory during Eye and Head Motion , 2002, The Journal of Neuroscience.
[16] Z. Wang,et al. Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity , 2001, Nature Medicine.
[17] C. Culmsee,et al. A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid β‐peptide , 2001 .
[18] M. Memo,et al. Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path? , 2001, Trends in Neurosciences.
[19] X. Wu,et al. Peg3/Pw1 promotes p53-mediated apoptosis by inducing Bax translocation from cytosol to mitochondria. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[20] I. Bechmann,et al. Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL) , 2000, The Lancet.
[21] H. Vanderstichele,et al. Aging Increased Amyloid Peptide and Caused Amyloid Plaques in Brain of Old APP/V717I Transgenic Mice by a Different Mechanism than Mutant Presenilin1 , 2000, The Journal of Neuroscience.
[22] S. Aizawa,et al. Role of p53 in DNA strand break‐induced apoptosis in organotypic slice culture from the mouse cerebellum , 2000, Journal of neuroscience research.
[23] T. Shea,et al. Beta-amyloid-induced calcium influx induces apoptosis in culture by oxidative stress rather than tau phosphorylation. , 2000, Brain research. Molecular brain research.
[24] D. Moechars,et al. Premature death in transgenic mice that overexpress a mutant amyloid precursor protein is preceded by severe neurodegeneration and apoptosis , 1999, Neuroscience.
[25] E. Alnemri,et al. Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor. , 1999, Cancer research.
[26] I. Herr,et al. CD95 Ligand (Fas-L/APO-1L) and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Mediate Ischemia-Induced Apoptosis in Neurons , 1999, The Journal of Neuroscience.
[27] Mark D. Johnson,et al. Evidence for involvement of Bax and p53, but not caspases, in radiation‐induced cell death of cultured postnatal hippocampal neurons , 1998, Journal of neuroscience research.
[28] D. Green. Apoptotic Pathways The Roads to Ruin , 1998, Cell.
[29] Xiaodong Wang,et al. Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors , 1998, Cell.
[30] Bruce A. Yankner,et al. Aging renders the brain vulnerable to amyloid β-protein neurotoxicity , 1998, Nature Medicine.
[31] John C. Lee,et al. Osteoprotegerin Is a Receptor for the Cytotoxic Ligand TRAIL* , 1998, The Journal of Biological Chemistry.
[32] M. Memo,et al. Induction of tumour‐suppressor phosphoprotein p53 in the apoptosis of cultured rat cerebellar neurones triggered by excitatory amino acids , 1998, The European journal of neuroscience.
[33] C. Smith,et al. The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. , 1997, Immunity.
[34] S. Srinivasula,et al. Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade , 1997, Cell.
[35] Henning Walczak,et al. TRAIL‐R2: a novel apoptosis‐mediating receptor for TRAIL , 1997, The EMBO journal.
[36] R. Gentz,et al. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. , 1997, Science.
[37] W I Wood,et al. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. , 1997, Science.
[38] V. Rotter,et al. Involvement of p53 in cell differentiation and development. , 1997, Biochimica et biophysica acta.
[39] M. Baudry,et al. Induction of Tumor Suppressor p53 and DNA Fragmentation in Organotypic Hippocampal Cultures Following Excitotoxin Treatment , 1997, Experimental Neurology.
[40] Arul M. Chinnaiyan,et al. The Receptor for the Cytotoxic Ligand TRAIL , 1997, Science.
[41] R. Neve,et al. Age-Dependent Neuronal and Synaptic Degeneration in Mice Transgenic for the C Terminus of the Amyloid Precursor Protein , 1996, The Journal of Neuroscience.
[42] D. Selkoe,et al. Amyloid β-Protein and the Genetics of Alzheimer's Disease* , 1996, The Journal of Biological Chemistry.
[43] S. Marsters,et al. Induction of Apoptosis by Apo-2 Ligand, a New Member of the Tumor Necrosis Factor Cytokine Family* , 1996, The Journal of Biological Chemistry.
[44] M. Peter,et al. Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor. , 1995, The EMBO journal.
[45] C. Gray,et al. Neurodegeneration mediated by glutamate and β-amyloid peptide: a comparison and possible interaction , 1995, Brain Research.
[46] R. Crumrine,et al. Attenuation of p53 Expression Protects against Focal Ischemic Damage in Transgenic Mice , 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[47] C. Cotman,et al. Rapid Communication: Ca2+ Channel Blockers Attenuate β‐Amyloid Peptide Toxicity to Cortical Neurons in Culture , 1994 .
[48] Carl W. Cotman,et al. Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[49] T. Lion,et al. Parental origin of chromosomes involved in the translocation t(9;22) , 1992, Nature.
[50] D. Selkoe,et al. Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids , 1992, Nature.
[51] D. Selkoe,et al. Amyloid β-peptide is produced by cultured cells during normal metabolism , 1992, Nature.
[52] C. Cotman,et al. β-Amyloid neurotoxicity: A discussion of in vitro findings , 1992, Neurobiology of Aging.
[53] D. Selkoe,et al. Mass spectrometry of purified amyloid beta protein in Alzheimer's disease. , 1992, The Journal of biological chemistry.
[54] M. Mattson,et al. beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[55] S. M. Sumi,et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD) , 1991, Neurology.
[56] L. Villa-komaroff,et al. Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease. , 1989, Science.
[57] M. Coletta,et al. Abeta(31-35) peptide induce apoptosis in PC 12 cells: contrast with Abeta(25-35) peptide and examination of underlying mechanisms. , 2005, Neurochemistry international.
[58] H. Levine. The Amyloid Hypothesis and the clearance and degradation of Alzheimer's beta-peptide. , 2004, Journal of Alzheimer's disease : JAD.
[59] M. Memo,et al. Neutralization of TRAIL death pathway protects human neuronal cell line from β-amyloid toxicity , 2003, Cell Death and Differentiation.
[60] A. Kowalska. Amyloid precursor protein gene mutations responsible for early-onset autosomal dominant Alzheimer's disease. , 2003, Folia neuropathologica.
[61] Q. Peng,et al. Pycnogenol protects neurons from amyloid-beta peptide-induced apoptosis. , 2002, Brain research. Molecular brain research.
[62] C. Geula,et al. Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity. , 1998, Nature medicine.
[63] I. Krantz,et al. KILLER/DR5 is a DNA damage–inducible p53–regulated death receptor gene , 1997, Nature Genetics.
[64] C. Cotman,et al. Ca2+ channel blockers attenuate beta-amyloid peptide toxicity to cortical neurons in culture. , 1994, Journal of neurochemistry.
[65] D. Teplow,et al. Amyloid beta-peptide is produced by cultured cells during normal metabolism. , 1992, Nature.
[66] Thomas Wisniewski,et al. Magnetic Resonance in Medicine 51:794–798 (2004) MRI Assessment of Neuropathology in a Transgenic Mouse Model of Alzheimer’s Disease , 2022 .