Predictive Value of UGT1A1 Polymorphisms in Irinotecan-Induced Toxicity and Therapeutic Efficacy in Colorectal Cancer Patients
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Xianglin Yuan | H. Qiu | Bo Liu | Ben Zhao | Lu Wang | Mingsheng Zhang | Qianqian Yu | Xiaoqi Nie | Qian-xia Li | Zhi-huan Li | Chen Gong | Xin Liao | Qian-qian Yu
[1] C. Tournigand,et al. FOLFIRI Followed by FOLFOX6 or the Reverse Sequence in Advanced Colorectal Cancer: A Randomized GERCOR Study , 2023, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[2] K. Higuchi,et al. Association between UGT1A1 gene polymorphism and safety and efficacy of irinotecan monotherapy as the third-line treatment for advanced gastric cancer , 2019, Gastric Cancer.
[3] A. Barnadas,et al. Pharmacogenetic clinical randomised phase II trial to evaluate the efficacy and safety of FOLFIRI with high-dose irinotecan (HD-FOLFIRI) in metastatic colorectal cancer patients according to their UGT1A 1 genotype , 2018, British Journal of Cancer.
[4] Astrid Gall,et al. Ensembl 2019 , 2018, Nucleic Acids Res..
[5] A. Jemal,et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries , 2018, CA: a cancer journal for clinicians.
[6] F. Huang,et al. UGT1A1*6 and UGT1A1*28 polymorphisms are correlated with irinotecan‐induced toxicity: A meta‐analysis , 2018, Asia-Pacific journal of clinical oncology.
[7] C. Xie,et al. UGT1A polymorphisms associated with worse outcome in colorectal cancer patients treated with irinotecan-based chemotherapy , 2018, Cancer Chemotherapy and Pharmacology.
[8] L. Boni,et al. DPYD and UGT1A1 genotyping to predict adverse events during first-line FOLFIRI or FOLFOXIRI plus bevacizumab in metastatic colorectal cancer , 2017, Oncotarget.
[9] Jiao-Er Zhang,et al. UGT1A1*6 polymorphisms are correlated with irinotecan-induced neutropenia: a systematic review and meta-analysis , 2017, Cancer Chemotherapy and Pharmacology.
[10] W. Duan,et al. Predictive Value of UGT1A1*28 Polymorphism In Irinotecan-based Chemotherapy , 2017, Journal of Cancer.
[11] Marco Peters,et al. Irinotecan-induced toxicity pharmacogenetics: an umbrella review of systematic reviews and meta-analyses , 2016, The Pharmacogenomics Journal.
[12] F. Innocenti,et al. Genotype-Guided Dosing Study of FOLFIRI plus Bevacizumab in Patients with Metastatic Colorectal Cancer , 2016, Clinical Cancer Research.
[13] A. Jemal,et al. Cancer treatment and survivorship statistics, 2016 , 2016, CA: a cancer journal for clinicians.
[14] N. Zhou,et al. UGT1A1 gene polymorphism is associated with toxicity and clinical efficacy of irinotecan-based chemotherapy in patients with advanced colorectal cancer , 2016, Cancer Chemotherapy and Pharmacology.
[15] H. Qiu,et al. Predictive effects of bilirubin on response of colorectal cancer to irinotecan-based chemotherapy. , 2016, World journal of gastroenterology.
[16] D. Pezet,et al. High Resectability Rate of Initially Unresectable Colorectal Liver Metastases After UGT1A1-Adapted High-Dose Irinotecan Combined with LV5FU2 and Cetuximab: A Multicenter Phase II Study (ERBIFORT) , 2016, Annals of Surgical Oncology.
[17] Y. Sasaki,et al. Irinotecan, a key chemotherapeutic drug for metastatic colorectal cancer. , 2015, World journal of gastroenterology.
[18] L. Dean. Irinotecan Therapy and UGT1A1 Genotype , 2015 .
[19] M. Loriot,et al. UGT1A1 genotype and irinotecan therapy: general review and implementation in routine practice , 2015, Fundamental & clinical pharmacology.
[20] M. Peake,et al. Stage at diagnosis and early mortality from cancer in England , 2015, British Journal of Cancer.
[21] Soma Das,et al. Dose-finding and pharmacokinetic study to optimize the dosing of irinotecan according to the UGT1A1 genotype of patients with cancer. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[22] J. Pignon,et al. The effect of the UGT1A1*28 allele on survival after irinotecan-based chemotherapy: a collaborative meta-analysis , 2014, The Pharmacogenomics Journal.
[23] Yali Lv,et al. Associations between UGT1A1*6 or UGT1A1*6/*28 polymorphisms and irinotecan-induced neutropenia in Asian cancer patients , 2014, Cancer Chemotherapy and Pharmacology.
[24] Ming Li,et al. UGT1A1*6 polymorphisms are correlated with irinotecan-induced toxicity: a system review and meta-analysis in Asians , 2014, Cancer Chemotherapy and Pharmacology.
[25] Qing Xu,et al. Analysis of UGT1A1*28 genotype and SN-38 pharmacokinetics for irinotecan-based chemotherapy in patients with advanced colorectal cancer: results from a multicenter, retrospective study in Shanghai , 2013, Journal of Cancer Research and Clinical Oncology.
[26] L. Shen,et al. UGT1A1*6/*28 polymorphisms could predict irinotecan-induced severe neutropenia not diarrhea in Chinese colorectal cancer patients , 2013, Medical Oncology.
[27] Xiang Liu,et al. Association of UGT1A1*28 polymorphisms with irinotecan-induced toxicities in colorectal cancer: a meta-analysis in Caucasians , 2013, The Pharmacogenomics Journal.
[28] Geoffrey Liu,et al. Association between UGT1A1*28 Polymorphisms and Clinical Outcomes of Irinotecan-Based Chemotherapies in Colorectal Cancer: A Meta-Analysis in Caucasians , 2013, PloS one.
[29] E. Bandrés,et al. Role of primary miRNA polymorphic variants in metastatic colon cancer patients treated with 5-fluorouracil and irinotecan , 2011, The Pharmacogenomics Journal.
[30] S. Gruber,et al. Clinical implications of UGT1A1*28 genotype testing in colorectal cancer patients , 2011, Cancer.
[31] A. Carrato,et al. UGT1A and TYMS genetic variants predict toxicity and response of colorectal cancer patients treated with first-line irinotecan and fluorouracil combination therapy , 2010, British Journal of Cancer.
[32] C. Strassburg. Gilbert-Meulengracht’s syndrome and pharmacogenetics: is jaundice just the tip of the iceberg? , 2010, Drug metabolism reviews.
[33] J. Crowley,et al. Phase III trial of irinotecan/cisplatin compared with etoposide/cisplatin in extensive-stage small-cell lung cancer: clinical and pharmacogenomic results from SWOG S0124. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[34] S. Litwin,et al. Pharmacokinetic analysis of irinotecan plus bevacizumab in patients with advanced solid tumors , 2009, Cancer Chemotherapy and Pharmacology.
[35] Jin-Hwang Liu,et al. UGT1A1*28 polymorphism predicts irinotecan‐induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma , 2008, Cancer.
[36] Teruhiko Yoshida,et al. Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28 , 2007, Pharmacogenetics and genomics.
[37] J. Panetta,et al. UGT1A1 promoter genotype correlates with SN-38 pharmacokinetics, but not severe toxicity in patients receiving low-dose irinotecan. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[38] Shih-Ming Huang,et al. Molecular pathogenesis of Gilbert's syndrome: decreased TATA-binding protein binding affinity of UGT1A1 gene promoter , 2007, Pharmacogenetics and genomics.
[39] M. Narabayashi,et al. Pharmacogenetic impact of polymorphisms in the coding region of the UGT1A1 gene on SN‐38 glucuronidation in Japanese patients with cancer , 2006, Cancer science.
[40] Giuseppe Toffoli,et al. The role of UGT1A1*28 polymorphism in the pharmacodynamics and pharmacokinetics of irinotecan in patients with metastatic colorectal cancer. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[41] V. Georgoulias,et al. Irinotecan (CPT-11) in Combination With Infusional 5-Fluorouracil and Leucovorin (de Gramont Regimen) as First-Line Treatment in Patients With Advanced Colorectal Cancer: A Multicenter Phase II Study , 2002, American journal of clinical oncology.
[42] H. Saka,et al. Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis. , 2000, Cancer research.
[43] E. Beutler,et al. Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism? , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[44] M. Ratain,et al. Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. , 1998, The Journal of clinical investigation.
[45] W. Rubinstein,et al. Irinotecan Therapy and UGT1A1 Genotype -- Medical Genetics Summaries , 2012 .
[46] M. Stauch,et al. Phase III trial of irinotecan plus infusional 5-fluorouracil/folinic acid versus irinotecan plus oxaliplatin as first-line treatment of advanced colorectal cancer. , 2011, European journal of cancer.
[47] Yoshiro Saito,et al. Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D. , 2003, Drug metabolism and disposition: the biological fate of chemicals.