Role of Phosphoinositide 3-Kinase and Endocytosis in Nerve Growth Factor-Induced Extracellular Signal-Regulated Kinase Activation via Ras and Rap1
暂无分享,去创建一个
E. Mccleskey | S. Grewal | P. Stork | R. D. York | P. Stenberg | Randall D. York | Edwin W. McCleskey | Philip J. S. Stork | Savraj S. Grewal | Derek C. Molliver | Paula E. Stenberg | D. Molliver | E. McCleskey
[1] M. Weber,et al. Partial purification of a mitogen-activated protein kinase kinase activator from bovine brain. Identification as B-Raf or a B-Raf-associated activity. , 1994, The Journal of biological chemistry.
[2] C. Marshall,et al. Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation , 1995, Cell.
[3] M. Quon,et al. Protein Kinase C-ζ and Phosphoinositide-dependent Protein Kinase-1 Are Required for Insulin-induced Activation of ERK in Rat Adipocytes* , 1999, The Journal of Biological Chemistry.
[4] R. Buscà,et al. Ras mediates the cAMP‐dependent activation of extracellular signal‐regulated kinases (ERKs) in melanocytes , 2000, The EMBO journal.
[5] D. Sarbassov,et al. Insulin receptor substrate-1 and phosphatidylinositol 3-kinase regulate extracellular signal-regulated kinase-dependent and -independent signaling pathways during myogenic differentiation. , 1998, Molecular endocrinology.
[6] D. Alessi,et al. Mitogen‐ and stress‐activated protein kinase‐1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB , 1998, The EMBO journal.
[7] S. Meakin,et al. The Signaling Adapter FRS-2 Competes with Shc for Binding to the Nerve Growth Factor Receptor TrkA , 1999, The Journal of Biological Chemistry.
[8] H. Yao,et al. cAMP Activates MAP Kinase and Elk-1 through a B-Raf- and Rap1-Dependent Pathway , 1997, Cell.
[9] S. DeArmond,et al. Nerve Growth Factor Signaling in Caveolae-like Domains at the Plasma Membrane* , 1999, The Journal of Biological Chemistry.
[10] F. L. Watson,et al. Trk Receptors Function As Rapid Retrograde Signal Carriers in the Adult Nervous System , 1997, The Journal of Neuroscience.
[11] S. Nakashima,et al. Effect of wortmannin and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) on N-formyl-methionyl-leucyl-phenylalanine-induced phospholipase D activation in differentiated HL60 cells: possible involvement of phosphatidylinositol 3-kinase in phospholipase D activation. , 1997, Biochemical pharmacology.
[12] A. Shaywitz,et al. CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. , 1999, Annual review of biochemistry.
[13] D. Holtzman,et al. Differential Effects of cAMP in Neurons and Astrocytes , 1999, The Journal of Biological Chemistry.
[14] J. Downward,et al. Role of Phosphoinositide 3-Kinase in Activation of Ras and Mitogen-Activated Protein Kinase by Epidermal Growth Factor , 1999, Molecular and Cellular Biology.
[15] L. Cantley,et al. Conditional Inhibition of the Mitogen-activated Protein Kinase Cascade by Wortmannin , 1997, The Journal of Biological Chemistry.
[16] M. Waterfield,et al. Signalling through phosphoinositide 3-kinases: the lipids take centre stage. , 1999, Current opinion in cell biology.
[17] C. Marshall,et al. Differential Regulation of Raf-1, A-Raf, and B-Raf by Oncogenic Ras and Tyrosine Kinases* , 1997, The Journal of Biological Chemistry.
[18] C. Der,et al. The Ras branch of small GTPases: Ras family members don't fall far from the tree. , 2000, Current opinion in cell biology.
[19] S. Grewal,et al. Extracellular-signal-regulated kinase signalling in neurons , 1999, Current Opinion in Neurobiology.
[20] W. Fantl,et al. Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase. , 1995, Science.
[21] Keigo Nishida,et al. Gab1 Acts as an Adapter Molecule Linking the Cytokine Receptor gp130 to ERK Mitogen-Activated Protein Kinase , 1998, Molecular and Cellular Biology.
[22] A. Riccio,et al. An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons. , 1997, Science.
[23] D. Bar-Sagi,et al. A Lipid-Anchored Grb2-Binding Protein That Links FGF-Receptor Activation to the Ras/MAPK Signaling Pathway , 1997, Cell.
[24] G. Landreth,et al. The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras , 1994, Molecular and cellular biology.
[25] D. Adam,et al. Inhibition of Receptor Internalization by Monodansylcadaverine Selectively Blocks p55 Tumor Necrosis Factor Receptor Death Domain Signaling* , 1999, The Journal of Biological Chemistry.
[26] S. Schmid,et al. Redundant and Distinct Functions for Dynamin-1 and Dynamin-2 Isoforms , 1998, The Journal of cell biology.
[27] S. Kuroda,et al. Purification of a Ras-dependent Mitogen-activated Protein Kinase Kinase Kinase from Bovine Brain Cytosol and Its Identification as a Complex of B-Raf and 14-3-3 Proteins (*) , 1995, The Journal of Biological Chemistry.
[28] H. Iba,et al. Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway. , 1998, Journal of cell science.
[29] T. Pestina,et al. Abnormal subcellular distribution of myosin and talin in Wistar Furth rat platelets. , 1995, Blood.
[30] M. Radeke,et al. Presence or absence of TrKA protein distinguishes subsets of small sensory neurons with unique cytochemical characteristics and dorsal horn projections , 1995, The Journal of comparative neurology.
[31] D J Glass,et al. Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. , 1999, Science.
[32] G. Panayotou,et al. Phosphoinositide 3-kinases: a conserved family of signal transducers. , 1997, Trends in biochemical sciences.
[33] J. de Gunzburg,et al. Association of the Ras-antagonistic Rap1/Krev-1 proteins with the Golgi complex. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[34] R. Abraham,et al. A Phosphatidylinositol 3-Kinase-dependent Pathway That Differentially Regulates c-Raf and A-Raf* , 1999, The Journal of Biological Chemistry.
[35] B. Geiger,et al. Alternative Intracellular Routing of ErbB Receptors May Determine Signaling Potency* , 1998, The Journal of Biological Chemistry.
[36] P. Hawkins,et al. Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase. , 1996, Journal of cell science.
[37] S. Bartlett,et al. Signalling events regulating the retrograde axonal transport of 125 I−βNerve growth factor in vivo , 1998, Brain Research.
[38] N. Miyasaka,et al. CrkL Mediates Ras-dependent Activation of the Raf/ERK Pathway through the Guanine Nucleotide Exchange Factor C3G in Hematopoietic Cells Stimulated with Erythropoietin or Interleukin-3* , 1999, The Journal of Biological Chemistry.
[39] W. Kolch,et al. Nerve Growth Factor-mediated Activation of the Mitogen-activated Protein (MAP) Kinase Cascade Involves a Signaling Complex Containing B-Raf and HSP90* , 1996, The Journal of Biological Chemistry.
[40] K. Guan,et al. Growth factor induced MEK activation is primarily mediated by an activator different from c-raf. , 1994, Biochemistry.
[41] J. Bos,et al. Rapid Ca2+‐mediated activation of Rap1 in human platelets , 1997, The EMBO journal.
[42] J. Blenis,et al. Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases , 1997, Oncogene.
[43] R. Lefkowitz,et al. The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor. , 2000, The Journal of biological chemistry.
[44] M. von Zastrow,et al. Dissociation of Functional Roles of Dynamin in Receptor-mediated Endocytosis and Mitogenic Signal Transduction* , 1999, The Journal of Biological Chemistry.
[45] D. Swanson,et al. AP1 Proteins Mediate the cAMP Response of the Dopamine β-Hydroxylase Gene* , 1998, The Journal of Biological Chemistry.
[46] Bevil R. Conway,et al. Cell Surface Trk Receptors Mediate NGF-Induced Survival While Internalized Receptors Regulate NGF-Induced Differentiation , 2000, The Journal of Neuroscience.
[47] A. King,et al. Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak , 2000, Current Biology.
[48] J. Bonifacino,et al. Co-localization of the TSC2 product tuberin with its target Rap1 in the Golgi apparatus. , 1996, Oncogene.
[49] K. Moelling,et al. Phosphorylation and regulation of Raf by Akt (protein kinase B). , 1999, Science.
[50] K. Nakamura,et al. Parietal cell MAP kinases: multiple activation pathways. , 1996, The American journal of physiology.
[51] G. Evan,et al. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB , 1997, Nature.
[52] M. Ehlers,et al. NGF-stimulated retrograde transport of trkA in the mammalian nervous system , 1995, The Journal of cell biology.
[53] W. Sellers,et al. Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[54] R. Lefkowitz,et al. The β2-Adrenergic Receptor Mediates Extracellular Signal-regulated Kinase Activation via Assembly of a Multi-receptor Complex with the Epidermal Growth Factor Receptor* , 2000, The Journal of Biological Chemistry.
[55] J. Groffen,et al. Enhancement of Guanine-Nucleotide Exchange Activity of C3G for Rap1 by the Expression of Crk, CrkL, and Grb2* , 1997, The Journal of Biological Chemistry.
[56] M. Caron,et al. Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase* , 1998, The Journal of Biological Chemistry.
[57] Eric R Kandel,et al. MAP Kinase Translocates into the Nucleus of the Presynaptic Cell and Is Required for Long-Term Facilitation in Aplysia , 1997, Neuron.
[58] Anthony J. Muslin,et al. Disruption of the 14-3-3 Binding Site within the B-Raf Kinase Domain Uncouples Catalytic Activity from PC12 Cell Differentiation* , 2000, The Journal of Biological Chemistry.
[59] J. Olefsky,et al. Nerve growth factor processing and trafficking events following TrkA-mediated endocytosis. , 1998, Endocrinology.
[60] D. Ginty,et al. Characterization of an NGF–P-TrkA Retrograde-Signaling Complex and Age-Dependent Regulation of TrkA Phosphorylation in Sympathetic Neurons , 1999, The Journal of Neuroscience.
[61] Simon C Watkins,et al. The Recruitment of Raf-1 to Membranes Is Mediated by Direct Interaction with Phosphatidic Acid and Is Independent of Association with Ras* , 2000, The Journal of Biological Chemistry.
[62] S. McMahon,et al. Immunocytochemical Localization of trkA Receptors in Chemically Identified Subgroups of Adult Rat Sensory Neurons , 1995, The European journal of neuroscience.
[63] N. Kimura,et al. Characterization of 17-beta-estradiol-dependent and -independent somatostatin receptor subtypes in rat anterior pituitary. , 1989, The Journal of biological chemistry.
[64] James R. Woodgett,et al. Protein kinases: Six degrees of separation? , 2000, Current Biology.
[65] T. Morimoto,et al. Endomembrane Trafficking of Ras The CAAX Motif Targets Proteins to the ER and Golgi , 1999, Cell.
[66] S. Schmid,et al. Regulation of signal transduction by endocytosis. , 2000, Current opinion in cell biology.
[67] I. Pastan,et al. Amantadine and dansylcadaverine inhibit vesicular stomatitis virus uptake and receptor-mediated endocytosis of alpha 2-macroglobulin. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[68] M. Zerial,et al. Association of Rap1a and Rap1b proteins with late endocytic/phagocytic compartments and Rap2a with the Golgi complex. , 1994, Journal of cell science.
[69] Lewis C. Cantley,et al. The Role of Phosphoinositide 3-Kinase Lipid Products in Cell Function* , 1999, The Journal of Biological Chemistry.
[70] H. Schaeffer,et al. Mitogen-Activated Protein Kinases: Specific Messages from Ubiquitous Messengers , 1999, Molecular and Cellular Biology.
[71] X. F. Zhang,et al. Raf meets Ras: completing the framework of a signal transduction pathway. , 1994, Trends in biochemical sciences.
[72] P. Barker,et al. p75 Neurotrophin Receptor Expression on Adult Human Oligodendrocytes: Signaling without Cell Death in Response to NGF , 1998, The Journal of Neuroscience.
[73] W. Mobley,et al. A signaling organelle containing the nerve growth factor-activated receptor tyrosine kinase, TrkA. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[74] J. Craig,et al. Recruitment of CREB Binding Protein Is Sufficient for CREB-Mediated Gene Activation , 2000, Molecular and Cellular Biology.
[75] A. Cuello,et al. A TrkA-selective, Fast Internalizing Nerve Growth Factor-Antibody Complex Induces Trophic but Not Neuritogenic Signals* , 1998, The Journal of Biological Chemistry.
[76] R. Campenot,et al. Retrograde Transport and Steady-State Distribution of 125I-Nerve Growth Factor in Rat Sympathetic Neurons in Compartmented Cultures , 1997, The Journal of Neuroscience.
[77] R. Lefkowitz,et al. Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[78] J. Brugge,et al. Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation , 1997, Molecular and cellular biology.
[79] E. Mccleskey,et al. Rap1 mediates sustained MAP kinase activation induced by nerve growth factor , 1998, Nature.
[80] H. Enslen,et al. Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity. , 1994, Genes & development.
[81] Richard G. W. Anderson,et al. Physical Association with Ras Enhances Activation of Membrane-bound Raf (RafCAAX)* , 1997, The Journal of Biological Chemistry.
[82] C. Desbois-Mouthon,et al. Insulin differentially regulates SAPKs/JNKs and ERKs in CHO cells overexpressing human insulin receptors. , 1998, Biochemical and biophysical research communications.
[83] David R. Kaplan,et al. Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt , 1997, Science.
[84] A. Lenferink,et al. Differential endocytic routing of homo‐ and hetero‐dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers , 1998, The EMBO journal.
[85] M. Scheid,et al. Phosphatidylinositol 3-OH Kinase Activity Is Not Required for Activation of Mitogen-activated Protein Kinase by Cytokines* , 1996, The Journal of Biological Chemistry.
[86] Richard G. W. Anderson,et al. Tyrosine Kinase Receptors Concentrated in Caveolae-like Domains from Neuronal Plasma Membrane* , 1997, The Journal of Biological Chemistry.
[87] B. Kahn,et al. Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes , 1997, Molecular and cellular biology.
[88] M. Greenberg,et al. Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation of CREB , 1994, Cell.
[89] K. Nakao,et al. Differential Activation of Mitogen-Activated Protein Kinase by Insulin and Epidermal Growth Factor in 3T3-L1 Adipocytes: A Possible Involvement of PI3-Kinase in the Activation of the MAP Kinase by Insulin , 1997, Diabetes.
[90] Y. Takai,et al. Tissue and subcellular distributions of the smg-21/rap1/Krev-1 proteins which are partly distinct from those of c-ras p21s , 1990, Molecular and cellular biology.
[91] S. Pyne,et al. The platelet-derived growth factor receptor stimulation of p42/p44 mitogen-activated protein kinase in airway smooth muscle involves a G-protein-mediated tyrosine phosphorylation of Gab1. , 2000, Molecular pharmacology.
[92] P. Cohen,et al. Insulin activates protein kinase B, inhibits glycogen synthase kinase‐3 and activates glycogen synthase by rapamycin‐insensitive pathways in skeletal muscle and adipose tissue , 1997, FEBS letters.
[93] Robert B. Campenot,et al. Rapid Retrograde Tyrosine Phosphorylation of trkA and Other Proteins in Rat Sympathetic Neurons in Compartmented Cultures , 1997, The Journal of cell biology.
[94] D. Pot,et al. A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain , 1997, Molecular and cellular biology.
[95] E. Mccleskey,et al. A Memory for Extracellular Ca2+ by Speeding Recovery of P2X Receptors from Desensitization , 1998, The Journal of Neuroscience.
[96] K. Siddle,et al. Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle: implications for glucose metabolism , 1997, Diabetologia.
[97] Tomohiko Maehama,et al. The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate* , 1998, The Journal of Biological Chemistry.
[98] P. Crespo,et al. Linkage of G Protein-Coupled Receptors to the MAPK Signaling Pathway Through PI 3-Kinase γ , 1997, Science.
[99] J. Olefsky,et al. Comparison of the intracellular itineraries of insulin-like growth factor-I and insulin and their receptors in Rat-1 fibroblasts. , 1994, Endocrinology.
[100] J L Benovic,et al. Role of Clathrin-mediated Endocytosis in Agonist-induced Down-regulation of the β2-Adrenergic Receptor* , 1998, The Journal of Biological Chemistry.
[101] P. Stork,et al. β2-Adrenergic Receptor Activates Extracellular Signal-regulated Kinases (ERKs) via the Small G Protein Rap1 and the Serine/Threonine Kinase B-Raf* , 2000, The Journal of Biological Chemistry.
[102] J. Dubochet,et al. On the preparation of cryosections for immunocytochemistry. , 1984, Journal of ultrastructure research.
[103] M. Wigler,et al. The lipid phosphatase activity of PTEN is critical for its tumor supressor function. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[104] J. Lavail,et al. Endocytosis of Activated TrkA: Evidence that Nerve Growth Factor Induces Formation of Signaling Endosomes , 1996, The Journal of Neuroscience.
[105] C. Marshall,et al. New Insights into the Interaction of Ras with the Plasma Membrane , 1999, Cell.
[106] G. Condorelli,et al. Insulin-like Growth Factor-I Receptor Internalization Regulates Signaling via the Shc/Mitogen-activated Protein Kinase Pathway, but Not the Insulin Receptor Substrate-1 Pathway* , 1998, The Journal of Biological Chemistry.
[107] T. Barber,et al. Negative regulation of the serine/threonine kinase B-Raf by Akt. , 2000, The Journal of biological chemistry.
[108] S. Schmid,et al. Control of EGF Receptor Signaling by Clathrin-Mediated Endocytosis , 1996, Science.
[109] Y. Takuwa,et al. Cyclin D1 Expression Mediated by Phosphatidylinositol 3-Kinase through mTOR-p70S6K-Independent Signaling in Growth Factor-Stimulated NIH 3T3 Fibroblasts , 1999, Molecular and Cellular Biology.
[110] A. Samanta,et al. Dansyl cadaverine regulates ligand induced endocytosis of interleukin‐8 receptor in human polymorphonuclear neutrophils , 1996, FEBS Letters.
[111] J. Kornhauser,et al. Nerve Growth Factor Activates Extracellular Signal-Regulated Kinase and p38 Mitogen-Activated Protein Kinase Pathways To Stimulate CREB Serine 133 Phosphorylation , 1998, Molecular and Cellular Biology.