Microneedles for delivery of anticancer therapeutics: recent trends and technologies

[1]  Guilan Quan,et al.  Microneedle-assisted vaccination combined with autophagy regulation for antitumor immunotherapy. , 2023, Journal of controlled release : official journal of the Controlled Release Society.

[2]  Yuhao Li,et al.  Research progress of advanced microneedle drug delivery system and its application in biomedicine. , 2023, Colloids and surfaces. B, Biointerfaces.

[3]  Mohd Imran,et al.  Cancer theranostics employing microneedles: Experimental and patented strategies , 2023, Journal of Drug Delivery Science and Technology.

[4]  Zhiai Xu,et al.  Engineered microneedle systems for topical cancer therapy , 2023, Applied Materials Today.

[5]  K. Kuotsu,et al.  Novel synergistic approaches of protein delivery through physical enhancement for transdermal microneedle drug delivery: A review , 2023, Journal of Drug Delivery Science and Technology.

[6]  S. Ramakrishna,et al.  Microneedles for Efficient and Precise Drug Delivery in Cancer Therapy , 2023, Pharmaceutics.

[7]  W. Cui,et al.  Recent advances in long-acting drug delivery systems for anticancer drug. , 2023, Advanced drug delivery reviews.

[8]  Yuqi Zhang,et al.  Microneedle-based transdermal detection and sensing devices. , 2023, Lab on a chip.

[9]  Miles A. Miller,et al.  Polymeric microneedles enable simultaneous delivery of cancer immunomodulatory drugs and detection of skin biomarkers , 2023, Theranostics.

[10]  Y. Anissimov,et al.  Intradermal injection of lidocaine with a microneedle device to provide rapid local anaesthesia for peripheral intravenous cannulation: A randomised open-label placebo-controlled clinical trial , 2022, PloS one.

[11]  P. Shende,et al.  Potential of transpapillary route for artesunate-loaded microneedles against breast cancer cell line , 2022, Colloids and Surfaces A: Physicochemical and Engineering Aspects.

[12]  H. Harn,et al.  Separable double-layered microneedle-based transdermal codelivery of DOX and LPS for synergistic immunochemotherapy of a subcutaneous glioma tumor , 2021, Chemical Engineering Journal.

[13]  Yuanjin Zhao,et al.  Bioinspired adhesive microneedle patch with gemcitabine encapsulation for pancreatic cancer treatment , 2021, Chemical Engineering Journal.

[14]  P. Prewett,et al.  An overview of microneedle applications, materials, and fabrication methods , 2021, Beilstein journal of nanotechnology.

[15]  Yixian Zhou,et al.  Intelligent and spatiotemporal drug release based on multifunctional nanoparticle-integrated dissolving microneedle system for synergetic chemo-photothermal therapy to eradicate melanoma. , 2021, Acta biomaterialia.

[16]  P. Kesharwani,et al.  Recent advances in microneedles-based drug delivery device in the diagnosis and treatment of cancer. , 2021, Journal of controlled release : official journal of the Controlled Release Society.

[17]  Wenjun Shan,et al.  Enhanced cancer immunotherapy by microneedle patch-assisted delivery of HBc VLPs based cancer vaccine , 2021 .

[18]  Michael R Hamblin,et al.  Diagnostic and drug release systems based on microneedle arrays in breast cancer therapy. , 2021, Journal of controlled release : official journal of the Controlled Release Society.

[19]  S. Desai,et al.  A Comprehensive Review of Microneedles: Types, Materials, Processes, Characterizations and Applications , 2021, Polymers.

[20]  H. Ashraf,et al.  Design, fabrication, and characterisation of a silicon microneedle array for transdermal therapeutic delivery using a single step wet etch process. , 2021, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[21]  Yufang Zhu,et al.  Recent advances in microneedles for tumor therapy and diagnosis , 2021 .

[22]  Zhihong Li,et al.  Recent advances on fabrication of microneedles on the flexible substrate , 2021, Journal of Micromechanics and Microengineering.

[23]  Shubiao Zhang,et al.  Microneedles for gene and drug delivery in skin cancer therapy. , 2021, Journal of controlled release : official journal of the Controlled Release Society.

[24]  W. Jiskoot,et al.  mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability , 2021, International Journal of Pharmaceutics.

[25]  T. M. Belete The Current Status of Gene Therapy for the Treatment of Cancer , 2021, Biologics : targets & therapy.

[26]  B. Mazzolai,et al.  Engineering Microneedle Patches for Improved Penetration: Analysis, Skin Models and Factors Affecting Needle Insertion , 2021, Nano-micro letters.

[27]  Guilan Quan,et al.  Recent advances in microneedles-mediated transdermal delivery of protein and peptide drugs , 2021, Acta pharmaceutica Sinica. B.

[28]  J. Jung,et al.  Microneedle for transdermal drug delivery: current trends and fabrication , 2021, Journal of Pharmaceutical Investigation.

[29]  A. Jemal,et al.  Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries , 2021, CA: a cancer journal for clinicians.

[30]  S. De Martino,et al.  One-Shot Fabrication of Polymeric Hollow Microneedles by Standard Photolithography , 2021, Polymers.

[31]  Maelíosa T. C. McCrudden,et al.  Enhancement strategies for transdermal drug delivery systems: current trends and applications , 2021, Drug Delivery and Translational Research.

[32]  R. Tade,et al.  Emerging era of microneedle array for pharmaceutical and biomedical applications: recent advances and toxicological perspectives , 2021, Future Journal of Pharmaceutical Sciences.

[33]  Sajjad Rahmani Dabbagh,et al.  3D-printed microneedles in biomedical applications , 2020, iScience.

[34]  Jie Wang,et al.  Preparation of Microneedle Array Mold Based on MEMS Lithography Technology , 2020, Micromachines.

[35]  Guilan Quan,et al.  Microneedle-mediated Transdermal Drug Delivery for Treating Diverse Skin Diseases. , 2020, Acta biomaterialia.

[36]  T. Okitsu,et al.  Flexible and porous microneedles of PDMS for continuous glucose monitoring , 2020, Biomedical Microdevices.

[37]  D. V. Gowda,et al.  Microneedles Drug Delivery Systems for Treatment of Cancer: A Recent Update , 2020, Pharmaceutics.

[38]  J. Hadžiabdić,et al.  Microneedles: Characteristics, Materials, Production Methods and Commercial Development , 2020, Micromachines.

[39]  Zhiqiang Lin,et al.  The microneedles carrying cisplatin and IR820 to perform synergistic chemo-photodynamic therapy against breast cancer , 2020, Journal of Nanobiotechnology.

[40]  Wei Xue,et al.  Dextran methacrylate hydrogel microneedles loaded with doxorubicin and trametinib for continuous transdermal administration of melanoma. , 2020, Carbohydrate polymers.

[41]  Mahima Singh,et al.  A review of recent advances in microneedle technology for transdermal drug delivery , 2020, Journal of Drug Delivery Science and Technology.

[42]  Yingjie Yu,et al.  Microneedles loaded with anti-PD-1-cisplatin nanoparticles for synergistic cancer immuno-chemotherapy. , 2020, Nanoscale.

[43]  S. Ahadian,et al.  Biodegradable microneedle patch for transdermal gene delivery. , 2020, Nanoscale.

[44]  M. Ashfaq,et al.  Recent advances on microneedle arrays-mediated technology in cancer diagnosis and therapy , 2020, Drug Delivery and Translational Research.

[45]  Uttam Kumar Mandal,et al.  Transdermal drug delivery system through polymeric microneedle: A recent update , 2020 .

[46]  Jong Seung Kim,et al.  Emerging combination strategies with phototherapy in cancer nanomedicine. , 2020, Chemical Society reviews.

[47]  Bo Hu,et al.  Therapeutic siRNA: state of the art , 2020, Signal Transduction and Targeted Therapy.

[48]  A. Cordeiro,et al.  Microneedle-Based Delivery: An Overview of Current Applications and Trends , 2020, Pharmaceutics.

[49]  P. Zhang,et al.  Rapidly dissolving microneedle patch for synergistic gene and photothermal therapy of subcutaneous tumor. , 2020, Journal of materials chemistry. B.

[50]  Z. Qian,et al.  Near-infrared responsive 5-fluorouracil and indocyanine green loaded MPEG-PCL nanoparticle integrated with dissolvable microneedle for skin cancer therapy , 2020, Bioactive materials.

[51]  J. Guan,et al.  Nanoparticle-based drug delivery systems for cancer therapy , 2020, Smart materials in medicine.

[52]  Wei Zhang,et al.  Local extraction and detection of early stage breast cancers through a microneedle and nano-Ag/MBL film based painless and blood-free strategy. , 2020, Materials science & engineering. C, Materials for biological applications.

[53]  Xin Pan,et al.  Construction of a Core-shell Microneedle System to Achieve Targeted Co-delivery of Checkpoint Inhibitors for Melanoma Immunotherapy. , 2020, Acta biomaterialia.

[54]  Shufen Cui,et al.  Polymeric microneedles for controlled transdermal drug delivery. , 2019, Journal of controlled release : official journal of the Controlled Release Society.

[55]  Peng Zhang,et al.  Cutaneous Microenvironment Responsive Microneedle Patch For Rapid Gene Release to Treat Subdermal Tumor. , 2019, Journal of controlled release : official journal of the Controlled Release Society.

[56]  Youngcheol Chae,et al.  A CMOS VEGF Sensor for Cancer Diagnosis Using a Peptide Aptamer-Based Functionalized Microneedle , 2019, IEEE Transactions on Biomedical Circuits and Systems.

[57]  J. Sheridan,et al.  Simple and customizable method for fabrication of high-aspect ratio microneedle molds using low-cost 3D printing , 2019, Microsystems & Nanoengineering.

[58]  Shubhmita Bhatnagar,et al.  Microneedle-based drug delivery: materials of construction , 2019, Journal of Chemical Sciences.

[59]  G. Wei,et al.  Recent progress in drug delivery , 2019, Acta pharmaceutica Sinica. B.

[60]  P. Singh,et al.  A review on parenteral delivery of peptides and proteins , 2019, Drug development and industrial pharmacy.

[61]  Andrew Reid,et al.  3D printed microneedle patches using stereolithography (SLA) for intradermal insulin delivery. , 2019, Materials science & engineering. C, Materials for biological applications.

[62]  Shuwang He,et al.  Recent progress of micro-needle formulations: Fabrication strategies and delivery applications , 2019, Journal of Drug Delivery Science and Technology.

[63]  Ming Kong,et al.  Enhanced transdermal lymphatic delivery of doxorubicin via hyaluronic acid based transfersomes/microneedle complex for tumor metastasis therapy. , 2019, International journal of biological macromolecules.

[64]  P. Kantoff,et al.  Phase III Trial of PROSTVAC in Asymptomatic or Minimally Symptomatic Metastatic Castration-Resistant Prostate Cancer , 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[65]  Shubhmita Bhatnagar,et al.  Dissolvable microneedle patch containing doxorubicin and docetaxel is effective in 4T1 xenografted breast cancer mouse model. , 2019, International journal of pharmaceutics.

[66]  M. Prausnitz,et al.  Rapidly separable microneedle patch for the sustained release of a contraceptive , 2019, Nature Biomedical Engineering.

[67]  Rachel S. Riley,et al.  Delivery technologies for cancer immunotherapy , 2019, Nature Reviews Drug Discovery.

[68]  Archana Akalkotkar,et al.  Evaluation of a Particulate Breast Cancer Vaccine Delivered via Skin , 2019, The AAPS Journal.

[69]  Chuanbin Wu,et al.  Coated microneedles mediated intradermal delivery of octaarginine/BRAF siRNA nanocomplexes for anti‐melanoma treatment , 2018, International journal of pharmaceutics.

[70]  Massimo Libra,et al.  Evolution of Cancer Pharmacological Treatments at the Turn of the Third Millennium , 2018, Front. Pharmacol..

[71]  Xi Xie,et al.  Microneedle-Mediated Delivery of Lipid-Coated Cisplatin Nanoparticles for Efficient and Safe Cancer Therapy. , 2018, ACS applied materials & interfaces.

[72]  Ji Hoon Jeong,et al.  Smart vaccine delivery based on microneedle arrays decorated with ultra-pH-responsive copolymers for cancer immunotherapy. , 2018, Biomaterials.

[73]  Jung-Hwan Park,et al.  Insertion‐responsive microneedles for rapid intradermal delivery of canine influenza vaccine , 2018, Journal of controlled release : official journal of the Controlled Release Society.

[74]  Yong Taik Lim,et al.  Enhanced Cancer Vaccination by In Situ Nanomicelle-Generating Dissolving Microneedles. , 2018, ACS nano.

[75]  Kanghyun Kim,et al.  Fabrication of Polymer Microstructures of Various Angles via Synchrotron X-Ray Lithography Using Simple Dimensional Transformation , 2018, Materials.

[76]  Joseph M. DeSimone,et al.  Spatially controlled coating of continuous liquid interface production microneedles for transdermal protein delivery , 2018, Journal of controlled release : official journal of the Controlled Release Society.

[77]  Yuqi Zhang,et al.  Punching and Electroporation for Enhanced Transdermal Drug Delivery , 2018, Theranostics.

[78]  Suyong Kim,et al.  Comparative Study of Two Droplet‐Based Dissolving Microneedle Fabrication Methods for Skin Vaccination , 2018, Advanced healthcare materials.

[79]  Shichang Zhao,et al.  Composite-dissolving microneedle patches for chemotherapy and photothermal therapy in superficial tumor treatment. , 2018, Biomaterials science.

[80]  P. Kumari,et al.  Zein Microneedles for Localized Delivery of Chemotherapeutic Agents to Treat Breast Cancer: Drug Loading, Release Behavior, and Skin Permeation Studies , 2018, AAPS PharmSciTech.

[81]  J. McBride,et al.  DNA vaccination for cervical cancer: Strategic optimisation of RALA mediated gene delivery from a biodegradable microneedle system , 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[82]  Zhen Gu,et al.  Polymeric microneedles for transdermal protein delivery☆ , 2018, Advanced drug delivery reviews.

[83]  Aydin Sadeqi,et al.  Low-cost and cleanroom-free fabrication of microneedles , 2018, Microsystems & Nanoengineering.

[84]  D. Weissman,et al.  mRNA vaccines — a new era in vaccinology , 2018, Nature Reviews Drug Discovery.

[85]  Ji Hoon Jeong,et al.  Microneedle arrays coated with charge reversal pH‐sensitive copolymers improve antigen presenting cells‐homing DNA vaccine delivery and immune responses , 2018, Journal of controlled release : official journal of the Controlled Release Society.

[86]  Koen van der Maaden,et al.  Hollow microneedle‐mediated micro‐injections of a liposomal HPV E743–63 synthetic long peptide vaccine for efficient induction of cytotoxic and T‐helper responses , 2018, Journal of controlled release : official journal of the Controlled Release Society.

[87]  Z. Qian,et al.  Microneedles-Based Transdermal Drug Delivery Systems: A Review. , 2017, Journal of biomedical nanotechnology.

[88]  Zhen Gu,et al.  A melanin-mediated cancer immunotherapy patch , 2017, Science Immunology.

[89]  Peng Chen,et al.  A Swellable Microneedle Patch to Rapidly Extract Skin Interstitial Fluid for Timely Metabolic Analysis , 2017, Advanced materials.

[90]  Feng Xu,et al.  Recent advances of controlled drug delivery using microfluidic platforms☆ , 2017, Advanced drug delivery reviews.

[91]  K. Ita Dissolving microneedles for transdermal drug delivery: Advances and challenges. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[92]  Jin-Ching Lee,et al.  Self-Assembly DNA Polyplex Vaccine inside Dissolving Microneedles for High-Potency Intradermal Vaccination , 2017, Theranostics.

[93]  Koen van der Maaden,et al.  Mesoporous Silica Nanoparticle-Coated Microneedle Arrays for Intradermal Antigen Delivery , 2017, Pharmaceutical Research.

[94]  M. Newton,et al.  Pilot study of safety and feasibility of DNA microseeding for treatment of spontaneous canine melanoma , 2017, Veterinary medicine and science.

[95]  Shanshan Qi,et al.  Co-delivery nanoparticles of anti-cancer drugs for improving chemotherapy efficacy , 2017, Drug delivery.

[96]  S. Pillai,et al.  Future Prospects for Scaffolding Methods and Biomaterials in Skin Tissue Engineering: A Review , 2016, International journal of molecular sciences.

[97]  I. Shimoyama,et al.  Scalable fabrication of microneedle arrays via spatially controlled UV exposure , 2016, Microsystems & Nanoengineering.

[98]  A. Jose,et al.  Transcutaneous iontophoretic delivery of STAT3 siRNA using layer-by-layer chitosan coated gold nanoparticles to treat melanoma. , 2016, Colloids and surfaces. B, Biointerfaces.

[99]  M. Meltzer,et al.  Assessing the Potential Cost-Effectiveness of Microneedle Patches in Childhood Measles Vaccination Programs: The Case for Further Research and Development , 2016, Drugs in R&D.

[100]  Joseph M. DeSimone,et al.  Single-Step Fabrication of Computationally Designed Microneedles by Continuous Liquid Interface Production , 2016, PloS one.

[101]  L. Tostanoski,et al.  In Vivo Expansion of Melanoma-Specific T Cells Using Microneedle Arrays Coated with Immune-Polyelectrolyte Multilayers , 2016, ACS biomaterials science & engineering.

[102]  Archana Akalkotkar,et al.  Evaluation of microparticulate ovarian cancer vaccine via transdermal route of delivery. , 2016, Journal of controlled release : official journal of the Controlled Release Society.

[103]  L. R. Aps,et al.  Bacterial spores as particulate carriers for gene gun delivery of plasmid DNA. , 2016, Journal of biotechnology.

[104]  R. Teague,et al.  Adapting Cancer Immunotherapy Models for the Real World. , 2016, Trends in immunology.

[105]  Ryan F. Donnelly,et al.  Microneedle arrays as transdermal and intradermal drug delivery systems: Materials science, manufacture and commercial development , 2016 .

[106]  Hui Li,et al.  Microneedles As a Delivery System for Gene Therapy , 2016, Front. Pharmacol..

[107]  Zhen Gu,et al.  Enhanced Cancer Immunotherapy by Microneedle Patch-Assisted Delivery of Anti-PD1 Antibody. , 2016, Nano letters.

[108]  Xuesi Chen,et al.  Co-delivery of chemotherapeutics and proteins for synergistic therapy. , 2016, Advanced drug delivery reviews.

[109]  B. Stoeber,et al.  Development and Validation of an Artificial Mechanical Skin Model for the Study of Interactions between Skin and Microneedles , 2016 .

[110]  Li Zhang,et al.  Transdermal Delivery of siRNA through Microneedle Array , 2016, Scientific Reports.

[111]  Yeu‐Chun Kim,et al.  Biomedical applications of microneedles in therapeutics: recent advancements and implications in drug delivery , 2016, Expert opinion on drug delivery.

[112]  H. McCarthy,et al.  Microneedles: an innovative platform for gene delivery , 2015, Drug Delivery and Translational Research.

[113]  Beatriz Clares,et al.  Enhancing topical analgesic administration: review and prospect for transdermal and transbuccal drug delivery systems. , 2015, Current pharmaceutical design.

[114]  Ryan F. Donnelly,et al.  Hydrogel-Forming Microneedles Prepared from “Super Swelling” Polymers Combined with Lyophilised Wafers for Transdermal Drug Delivery , 2014, PloS one.

[115]  Viness Pillay,et al.  Current advances in the fabrication of microneedles for transdermal delivery. , 2014, Journal of controlled release : official journal of the Controlled Release Society.

[116]  Benjamin C. Tang,et al.  Microneedle Electrodes Toward an Amperometric Glucose‐Sensing Smart Patch , 2014, Advanced healthcare materials.

[117]  Conor O'Mahony,et al.  Production of dissolvable microneedles using an atomised spray process: effect of microneedle composition on skin penetration. , 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[118]  Daniel Anderson,et al.  Delivery materials for siRNA therapeutics. , 2013, Nature materials.

[119]  Hyungil Jung,et al.  Droplet-born air blowing: novel dissolving microneedle fabrication. , 2013, Journal of controlled release : official journal of the Controlled Release Society.

[120]  Mark G. Allen,et al.  Hollow microneedles for intradermal injection fabricated by sacrificial micromolding and selective electrodeposition , 2013, Biomedical microdevices.

[121]  Christopher H Contag,et al.  Gene silencing following siRNA delivery to skin via coated steel microneedles: In vitro and in vivo proof-of-concept. , 2013, Journal of controlled release : official journal of the Controlled Release Society.

[122]  Ryan F. Donnelly,et al.  Skin Dendritic Cell Targeting via Microneedle Arrays Laden with Antigen-Encapsulated Poly-d,l-lactide-co-Glycolide Nanoparticles Induces Efficient Antitumor and Antiviral Immune Responses , 2013, ACS nano.

[123]  Nouri Nayerossadat,et al.  Viral and nonviral delivery systems for gene delivery , 2012, Advanced biomedical research.

[124]  Ryan F. Donnelly,et al.  Microneedle-mediated Transdermal and Intradermal Drug Delivery , 2012 .

[125]  José Juan Escobar-Chávez,et al.  Microneedles: A Valuable Physical Enhancer to Increase Transdermal Drug Delivery , 2011, Journal of clinical pharmacology.

[126]  P. Selvaraj,et al.  A novel microparticulate vaccine for melanoma cancer using transdermal delivery , 2011, Journal of microencapsulation.

[127]  D. Leake,et al.  Silencing of reporter gene expression in skin using siRNAs and expression of plasmid DNA delivered by a soluble protrusion array device (PAD). , 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

[128]  Ryuji Morita,et al.  Metal microneedle fabrication using twisted light with spin. , 2010, Optics express.

[129]  Hervé Bourhy,et al.  Safety and efficacy of novel dermal and epidermal microneedle delivery systems for rabies vaccination in healthy adults. , 2010, Vaccine.

[130]  Damijan Miklavcic,et al.  Hollow Microneedle Arrays for Intradermal Drug Delivery and DNA Electroporation , 2010, The Journal of Membrane Biology.

[131]  R. Donnelly,et al.  Microneedle-based drug delivery systems: Microfabrication, drug delivery, and safety , 2010, Drug delivery.

[132]  Aleksandr Ovsianikov,et al.  Two-photon polymerization of microneedles for transdermal drug delivery , 2010, Expert opinion on drug delivery.

[133]  Mark E. Davis,et al.  Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles , 2010, Nature.

[134]  M. Prausnitz,et al.  Cutaneous vaccination using microneedles coated with hepatitis C DNA vaccine , 2010, Gene Therapy.

[135]  Ryan F. Donnelly,et al.  Microneedle Arrays Allow Lower Microbial Penetration Than Hypodermic Needles In Vitro , 2009, Pharmaceutical Research.

[136]  M. Prausnitz,et al.  Minimally invasive insulin delivery in subjects with type 1 diabetes using hollow microneedles. , 2009, Diabetes technology & therapeutics.

[137]  Aleksandr Ovsianikov,et al.  Fabrication of Polymer Microneedles Using a Two-Photon Polymerization and Micromolding Process , 2009, Journal of diabetes science and technology.

[138]  Mark R. Prausnitz,et al.  Effect of Microneedle Design on Pain in Human Volunteers , 2008, The Clinical journal of pain.

[139]  T. Tanner,et al.  Delivering drugs by the transdermal route: review and comment , 2008, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[140]  Yuqin Qiu,et al.  Enhancement of skin permeation of docetaxel: a novel approach combining microneedle and elastic liposomes. , 2008, Journal of controlled release : official journal of the Controlled Release Society.

[141]  J. Birchall,et al.  Gene Delivery to the Epidermal Cells of Human Skin Explants Using Microfabricated Microneedles and Hydrogel Formulations , 2008, Pharmaceutical Research.

[142]  Seiji Aoyagi,et al.  Laser fabrication of high aspect ratio thin holes on biodegradable polymer and its application to a microneedle , 2007 .

[143]  M. Prausnitz,et al.  Does Needle Size Matter? , 2007, Journal of diabetes science and technology.

[144]  C. Meinhart,et al.  Bulk Micromachined Titanium Microneedles , 2007, Journal of Microelectromechanical Systems.

[145]  Mark R Prausnitz,et al.  Coated microneedles for transdermal delivery. , 2007, Journal of controlled release : official journal of the Controlled Release Society.

[146]  L. Brown Commercial challenges of protein drug delivery , 2005, Expert opinion on drug delivery.

[147]  T. Albert,et al.  Is galvanic corrosion between titanium alloy and stainless steel spinal implants a clinical concern? , 2004, The spine journal : official journal of the North American Spine Society.

[148]  Wijaya Martanto,et al.  Transdermal Delivery of Insulin Using Microneedles in Vivo , 2004, Pharmaceutical Research.

[149]  Diane E. Sutter,et al.  Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery , 2002, Nature Medicine.

[150]  M. Allen,et al.  Microfabricated microneedles: a novel approach to transdermal drug delivery. , 1998, Journal of pharmaceutical sciences.

[151]  T. Christenson,et al.  Fabrication of assembled micromechanical components via deep X-ray lithography , 1991, [1991] Proceedings. IEEE Micro Electro Mechanical Systems.

[152]  Fubing Wang,et al.  A self-monitoring microneedle patch for light-controlled synergistic treatment of melanoma. , 2023, Bioactive materials.

[153]  B. Qiu,et al.  Flav7 + DOX co-loaded separable microneedle for light-triggered chemo-thermal therapy of superficial tumors , 2022 .

[154]  MICRONEEDLES FOR INTRADERMAL DELIVERY OF CANCER VACCINES , 2021 .

[155]  M. M. Pandey,et al.  Microneedles: A smart approach and increasing potential for transdermal drug delivery system. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[156]  T. Tzai,et al.  Transdermal Delivery of Luteinizing Hormone-releasing Hormone with Chitosan Microneedles: A Promising Tool for Androgen Deprivation Therapy. , 2017, Anticancer research.

[157]  K. Duffy,et al.  Facial allergic granulomatous reaction and systemic hypersensitivity associated with microneedle therapy for skin rejuvenation. , 2014, JAMA dermatology.

[158]  David E. Golan,et al.  Protein therapeutics: a summary and pharmacological classification , 2008, Nature Reviews Drug Discovery.

[159]  Boris N. Chichkov,et al.  Two Photon Polymerization of Polymer–Ceramic Hybrid Materials for Transdermal Drug Delivery , 2007 .

[160]  P. V. Subramanyam,et al.  ON MICRONEEDLES : AN EMERGING TRANSDERMAL DRUG DELIVERY SYSTEM , 2022 .