A Case of Anti-Jk(a) Whose Reactivity Was Abolished in an Enzyme Gel Test

We report a case of anti-Jk, whose reactivity was abolished in an enzyme gel test. A 56-year-old woman was admitted to our hospital because of fever, myalgia, nausea and vomiting. Anti-Jk was detected by antibody screening and an identification test using a LISS/Coombs gel card (DiaMed AG, Cressier sur Morat, Switzwerland). Its reactivity was so weak (trace 1+) that an Enzyme gel card (DiaMed AG) was added to enhance the reactivity. Unexpectedly, all reactions with the enzyme-treated cells showed negative results. The patient’s RBC phenotype was Jk(a-b+). The abdominal CT revealed a 67.5 cm sized liver abscess. Her condition improved after percutaneous catheter drainage and she was discharged on the 23 hospital day.