Ultrasensitive regulation of anapleurosis via allosteric activation of PEP carboxylase

[1]  U. Sauer,et al.  Large-scale 13C-flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli , 2011, Molecular systems biology.

[2]  Daniel Amador-Noguez,et al.  Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer. , 2010, Analytical chemistry.

[3]  Judith B. Zaugg,et al.  Bacterial adaptation through distributed sensing of metabolic fluxes , 2010, Molecular systems biology.

[4]  T. Cooper,et al.  The quaternary structure of pyruvate kinase type 1 from Escherichia coli at low nanomolar concentrations. , 2010, Biochimie.

[5]  J. Rabinowitz,et al.  Absolute Metabolite Concentrations and Implied Enzyme Active Site Occupancy in Escherichia coli , 2009, Nature chemical biology.

[6]  A. Joachimiak,et al.  Structural and Biochemical Characterization of the Type II Fructose-1,6-bisphosphatase GlpX from Escherichia coli* , 2009, Journal of Biological Chemistry.

[7]  Matthias Reuss,et al.  In vivo dynamics of glycolysis in Escherichia coli shows need for growth‐rate dependent metabolome analysis , 2008, Biotechnology progress.

[8]  J. Rabinowitz,et al.  Analytical strategies for LC-MS-based targeted metabolomics. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[9]  J. Rabinowitz,et al.  Absolute quantitation of intracellular metabolite concentrations by an isotope ratio-based approach , 2008, Nature Protocols.

[10]  J. Rabinowitz,et al.  Kinetic flux profiling for quantitation of cellular metabolic fluxes , 2008, Nature Protocols.

[11]  Ru Wei,et al.  The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth , 2008, Nature.

[12]  J. Rabinowitz,et al.  Differentiating metabolites formed from de novo synthesis versus macromolecule decomposition. , 2007, Journal of the American Chemical Society.

[13]  J. Rabinowitz,et al.  Acidic acetonitrile for cellular metabolome extraction from Escherichia coli. , 2007, Analytical chemistry.

[14]  Adam M. Feist,et al.  A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information , 2007, Molecular systems biology.

[15]  Pei Yee Ho,et al.  Multiple High-Throughput Analyses Monitor the Response of E. coli to Perturbations , 2007, Science.

[16]  Masaru Tomita,et al.  Inhibitory effect of phosphoenolpyruvate on glycolytic enzymes in Escherichia coli. , 2007, Research in microbiology.

[17]  M. Mann,et al.  In-gel digestion for mass spectrometric characterization of proteins and proteomes , 2006, Nature Protocols.

[18]  Matthew J. Brauer,et al.  Conservation of the metabolomic response to starvation across two divergent microbes , 2006, Proceedings of the National Academy of Sciences.

[19]  H. Mori,et al.  Molecular Basis of Formaldehyde Detoxification , 2006, Journal of Biological Chemistry.

[20]  H. Mori,et al.  Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection , 2006, Molecular systems biology.

[21]  H. Mori,et al.  Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological research. , 2006, DNA research : an international journal for rapid publication of reports on genes and genomes.

[22]  Uwe Sauer,et al.  The PEP-pyruvate-oxaloacetate node as the switch point for carbon flux distribution in bacteria. , 2005, FEMS microbiology reviews.

[23]  R. Christopherson,et al.  Dihydroorotase from Escherichia coli: loop movement and cooperativity between subunits. , 2005, Journal of molecular biology.

[24]  Masaaki Kotera,et al.  Maize Phosphoenolpyruvate Carboxylase , 2005, Journal of Biological Chemistry.

[25]  M. Araúzo-Bravo,et al.  Effect of a pyruvate kinase (pykF-gene) knockout mutation on the control of gene expression and metabolic fluxes in Escherichia coli. , 2004, FEMS microbiology letters.

[26]  Y. Kai,et al.  Phosphoenolpyruvate carboxylase: a new era of structural biology. , 2004, Annual review of plant biology.

[27]  Hirotada Mori,et al.  Effect of zwf gene knockout on the metabolism of Escherichia coli grown on glucose or acetate. , 2004, Metabolic engineering.

[28]  M. Araúzo-Bravo,et al.  Metabolic flux analysis of pykF gene knockout Escherichia coli based on 13C-labeling experiments together with measurements of enzyme activities and intracellular metabolite concentrations , 2004, Applied Microbiology and Biotechnology.

[29]  O. Fiehn.  Metabolomics – the link between genotypes and phenotypes , 2004, Plant Molecular Biology.

[30]  D. Kern,et al.  The role of dynamics in allosteric regulation. , 2003, Current opinion in structural biology.

[31]  U. Sauer,et al.  A Novel Metabolic Cycle Catalyzes Glucose Oxidation and Anaplerosis in Hungry Escherichia coli* , 2003, Journal of Biological Chemistry.

[32]  Steady-state kinetics and molecular evolution of Escherichia coli MenD [(1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase], an anomalous thiamin diphosphate-dependent decarboxylase-carboligase. , 2003, Biochemistry.

[33]  Y. Kai,et al.  Phosphoenolpyruvate carboxylase: three-dimensional structure and molecular mechanisms. , 2003, Archives of biochemistry and biophysics.

[34]  K. Shimizu,et al.  Global metabolic regulation analysis for Escherichia coli K12 based on protein expression by 2-dimensional electrophoresis and enzyme activity measurement , 2003, Applied Microbiology and Biotechnology.

[35]  Katy C. Kao,et al.  Global Expression Profiling of Acetate-grown Escherichia coli * , 2002, The Journal of Biological Chemistry.

[36]  E. Stadtman.  The Story of Glutamine Synthetase Regulation , 2001, The Journal of Biological Chemistry.

[37]  M. Reuss,et al.  In vivo analysis of metabolic dynamics in Saccharomyces cerevisiae : I. Experimental observations. , 1997, Biotechnology and bioengineering.

[38]  H. Salleh,et al.  Essential cysteines in 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase from Escherichia coli: analysis by chemical modification and site-directed mutagenesis. , 1996, Biochemistry.

[39]  C. Walsh,et al.  Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin. , 1996, Biochemistry.

[40]  K. Herrmann.  The Shikimate Pathway as an Entry to Aromatic Secondary Metabolism , 1995, Plant physiology.

[41]  E. Eisenstein,et al.  Cooperative binding of the feedback modifiers isoleucine and valine to biosynthetic threonine deaminase from Escherichia coli. , 1994, The Journal of biological chemistry.

[42]  S. Jackowski,et al.  Kinetics and regulation of pantothenate kinase from Escherichia coli. , 1994, The Journal of biological chemistry.

[43]  D. Koshland,et al.  Branch point control by the phosphorylation state of isocitrate dehydrogenase. A quantitative examination of fluxes during a regulatory transition. , 1985, The Journal of biological chemistry.

[44]  N. Fujita,et al.  Phosphoenolpyruvate carboxylase of Escherichia coli. Specificity of some compounds as activators at the site for fructose 1,6-bisphosphate, one of the allosteric effectors. , 1984, Journal of biochemistry.

[45]  M. Takahashi,et al.  Fluorescence studies of threonine-promoted conformational transitions in aspartokinase I using the substrate analogue 2'(3')-O-(2,4,6-trinitrophenyl)adenosine 5'-triphosphate. , 1983, The Journal of biological chemistry.

[46]  K. Izui,et al.  Regulation of Escherichia coli phosphoenolpyruvate carboxylase by multiple effectors in vivo. II. Kinetic studies with a reaction system containing physiological concentrations of ligands. , 1981, Journal of biochemistry.

[47]  K. Izui,et al.  Regulation of Escherichia coli phosphoenolpyruvate carboxylase by multiple effectors in vivo. Estimation of the activities in the cells grown on various compounds. , 1980, Journal of biochemistry.

[48]  H. Reeves,et al.  Phosphorylation of Isocitrate dehydrogenase of Escherichia coli. , 1979, Science.

[49]  R. Silverstein,et al.  Concerted regulation in vitro of phosphoenolpyruvate carboxylase from Escherichia coli. , 1973, The Journal of biological chemistry.

[50]  G. Markus,et al.  Phosphoenolpyruvate carboxylase of Escherichia coli. Purification and some properties. , 1972, The Journal of biological chemistry.

[51]  Bruce N. Ames,et al.  Compounds Which Serve as the Sole Source of Carbon or Nitrogen for Salmonella typhimurium LT-2 , 1969, Journal of bacteriology.

[52]  B. Sanwal,et al.  Regulation of the activity of phosphoenolypyruvate carboxylase by fructose diphosphate. , 1966, Biochemical and biophysical research communications.