Time-dependent cellular and transcriptional changes in the osteoblast lineage associated with sclerostin antibody treatment in ovariectomized rats.
暂无分享,去创建一个
Yudong D. He | C. Afshari | P. Nioi | R. Hu | I. Pyrah | R. Boyce | T. Wronski | M. Ominsky | Danielle L Brown | Scott Taylor | Efrain Pacheco | S. Buntich | J. Aguirre | Yudong He | Danielle L. Brown
[1] M. Stolina,et al. Differential temporal effects of sclerostin antibody and parathyroid hormone on cancellous and cortical bone and quantitative differences in effects on the osteoblast lineage in young intact rats. , 2015, Bone.
[2] Yudong D. He,et al. Transcriptional Profiling of Laser Capture Microdissected Subpopulations of the Osteoblast Lineage Provides Insight Into the Early Response to Sclerostin Antibody in Rats , 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[3] D. Kohn,et al. WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling* , 2015, The Journal of Biological Chemistry.
[4] D. Burr,et al. Osteocytes mediate the anabolic actions of canonical Wnt/β-catenin signaling in bone , 2015, Proceedings of the National Academy of Sciences.
[5] T. Mikkelsen,et al. The Regulatory Landscape of Osteogenic Differentiation , 2014, Stem cells.
[6] P. Kostenuik,et al. Temporal changes in systemic and local expression of bone turnover markers during six months of sclerostin antibody administration to ovariectomized rats. , 2014, Bone.
[7] P. Kostenuik,et al. Progressive increases in bone mass and bone strength in an ovariectomized rat model of osteoporosis after 26 weeks of treatment with a sclerostin antibody. , 2014, Endocrinology.
[8] Xuan-Yin Chen,et al. Let-7g reverses malignant phenotype of osteosarcoma cells by targeting Aurora-B. , 2014, International journal of clinical and experimental pathology.
[9] Y. Katayama,et al. Regulation of hematopoiesis in endosteal microenvironments , 2014, International Journal of Hematology.
[10] Cesar Libanati,et al. Romosozumab in postmenopausal women with low bone mineral density , 2014, The New England journal of medicine.
[11] Andreas Krämer,et al. Causal analysis approaches in Ingenuity Pathway Analysis , 2013, Bioinform..
[12] Jeffrey L. Wrana,et al. Signal integration in TGF-β, WNT, and Hippo pathways , 2013, F1000prime reports.
[13] W. Richards,et al. Sclerostin and Dickkopf-1 as therapeutic targets in bone diseases. , 2012, Endocrine reviews.
[14] Hai Qing,et al. Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[15] N. Kim,et al. MiRNA-34 intrinsically links p53 tumor suppressor and Wnt signaling , 2012, Cell cycle.
[16] Nam-Gyun Kim,et al. p53 and MicroRNA-34 Are Suppressors of Canonical Wnt Signaling , 2011, Science Signaling.
[17] Lynda F. Bonewald,et al. Sclerostin Stimulates Osteocyte Support of Osteoclast Activity by a RANKL-Dependent Pathway , 2011, PloS one.
[18] E. Posvar,et al. Single‐dose, placebo‐controlled, randomized study of AMG 785, a sclerostin monoclonal antibody , 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[19] H. Saya,et al. c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis , 2010, Oncogene.
[20] H. Smeets,et al. Wnt5b stimulates adipogenesis by activating PPARgamma, and inhibiting the beta-catenin dependent Wnt signaling pathway together with Wnt5a. , 2009, Biochemical and biophysical research communications.
[21] H. Kwak,et al. GM-CSF Regulates Fusion of Mononuclear Osteoclasts into Bone-Resorbing Osteoclasts by Activating the Ras/ERK Pathway1 , 2009, The Journal of Immunology.
[22] Steve Horvath,et al. WGCNA: an R package for weighted correlation network analysis , 2008, BMC Bioinformatics.
[23] P. Williams. A single dose , 2008, BDJ.
[24] T. Yuan,et al. The Retinoblastoma Protein Tumor Suppressor Is Important for Appropriate Osteoblast Differentiation and Bone Development , 2008, Molecular Cancer Research.
[25] Matthew R Allen,et al. Mechanical Stimulation of Bone in Vivo Reduces Osteocyte Expression of Sost/Sclerostin* , 2008, Journal of Biological Chemistry.
[26] K. Coombes,et al. Identification of Cell Cycle Regulatory Genes as Principal Targets of p53-mediated Transcriptional Repression* , 2006, Journal of Biological Chemistry.
[27] Stephen N. Jones,et al. Osteoblast differentiation and skeletal development are regulated by Mdm2–p53 signaling , 2006, The Journal of cell biology.
[28] Z. Weng,et al. A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome , 2006, Cell.
[29] Qiang Wu,et al. p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling , 2006, The Journal of cell biology.
[30] J. Reeve,et al. The FASEB Journal express article 10.1096/fj.05-4221fje. Published online August 25, 2005. ©2005 FASEB , 2022 .
[31] J. Wysolmerski,et al. TOPGAL Mice Show That the Canonical Wnt Signaling Pathway Is Active During Bone Development and Growth and Is Activated by Mechanical Loading In Vitro , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[32] Hans Clevers,et al. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. , 2005, Developmental cell.
[33] Asif J. Chaudhry,et al. Ras-Raf-Arf Signaling Critically Depends on the Dmp1 Transcription Factor , 2005, Molecular and Cellular Biology.
[34] M. Justice,et al. A twist code determines the onset of osteoblast differentiation. , 2004, Developmental cell.
[35] John A Latham,et al. Osteocyte control of bone formation via sclerostin, a novel BMP antagonist , 2003, The EMBO journal.
[36] M. West,et al. Distinct gene expression phenotypes of cells lacking Rb and Rb family members. , 2003, Cancer research.
[37] M. van Lohuizen,et al. The T-box Repressors TBX2 and TBX3Specifically Regulate the Tumor Suppressor Genep14 ARF via a Variant T-site in the Initiator* , 2002, The Journal of Biological Chemistry.
[38] T. Volkert,et al. E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints. , 2002, Genes & development.
[39] Toshitaka Nakamura,et al. Disruption of the p53 Gene Results in Preserved Trabecular Bone Mass and Bone Formation After Mechanical Unloading , 2002, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[40] Charles J. Sherr,et al. The INK4a/ARF network in tumour suppression , 2001, Nature Reviews Molecular Cell Biology.
[41] N. Athanasou,et al. The effect of macrophage-colony stimulating factor and other humoral factors (interleukin-1, -3, -6, and -11, tumor necrosis factor-alpha, and granulocyte macrophage-colony stimulating factor) on human osteoclast formation from circulating cells. , 2001, Bone.
[42] T. Takano-Yamamoto,et al. A three-dimensional distribution of osteocyte processes revealed by the combination of confocal laser scanning microscopy and differential interference contrast microscopy. , 2001, Bone.
[43] Marc J. van de Vijver,et al. Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19ARF) and is amplified in a subset of human breast cancers , 2000, Nature Genetics.
[44] Jian Wang,et al. Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53 , 2000, Oncogene.
[45] R. Eisenman,et al. c-Myc enhances protein synthesis and cell size during B lymphocyte development. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[46] L. Kedes,et al. Twist is a potential oncogene that inhibits apoptosis. , 1999, Genes & development.
[47] A. Sparks,et al. Identification of c-MYC as a target of the APC pathway. , 1998, Science.
[48] A. Wetterwald,et al. Role of CSF‐1 in bone and bone marrow development , 1997, Molecular reproduction and development.
[49] M. Forwood,et al. Inducible cyclo‐oxygenase (COX‐2) mediates the induction of bone formation by mechanical loading in vivo , 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[50] R. Mehta,et al. Skeletal effects of calcitonin in ovariectomized rats. , 1991, Endocrinology.
[51] H. Frost. Bone “mass” and the “mechanostat”: A proposal , 1987, The Anatomical record.
[52] H. Gundersen. Stereology of arbitrary particles * , 1986, Journal of microscopy.
[53] D. C. Sterio. The unbiased estimation of number and sizes of arbitrary particles using the disector , 1984, Journal of microscopy.
[54] T. Bellido. Osteocyte-Driven Bone Remodeling , 2013, Calcified Tissue International.
[55] Luquan Wang,et al. Generation of p53 target database via integration of microarray and global p53 DNA-binding site analysis. , 2004, Methods in molecular biology.