Pyrogenic synthetic amorphous silica (NM-203): Genotoxicity in rats following sub-chronic oral exposure.

[1]  F. Maranghi,et al.  Effects of sub-chronic oral exposure to pyrogenic synthetic amorphous silica (NM-203) in male and female Sprague-Dawley rats: focus on reproductive systems. , 2021, Reproductive toxicology.

[2]  Yaxin Deng,et al.  Genotoxicity evaluation of silica nanoparticles in murine: a systematic review and meta-analysis , 2021, Toxicology mechanisms and methods.

[3]  Soo-Jin Choi,et al.  Determination of Two Differently Manufactured Silicon Dioxide Nanoparticles by Cloud Point Extraction Approach in Intestinal Cells, Intestinal Barriers and Tissues , 2021, International journal of molecular sciences.

[4]  A. Oomen,et al.  Issues currently complicating the risk assessment of synthetic amorphous silica (SAS) nanoparticles after oral exposure , 2021, Nanotoxicology.

[5]  F. Maranghi,et al.  Amorphous silica nanoparticles induced spleen and liver toxicity after acute intravenous exposure in male and female rats , 2021, Toxicology and industrial health.

[6]  Rehab A. Azouz,et al.  Toxic Impacts of Amorphous Silica Nanoparticles on Liver and Kidney of Male Adult Rats: an In Vivo Study , 2020, Biological Trace Element Research.

[7]  A. Zijno,et al.  Use of a common European approach for nanomaterials’ testing to support regulation: a case study on titanium and silicon dioxide representative nanomaterials , 2020, Journal of applied toxicology : JAT.

[8]  D. Passeri,et al.  Determination of Total Silicon and SiO2 Particles Using an ICP-MS Based Analytical Platform for Toxicokinetic Studies of Synthetic Amorphous Silica , 2020, Nanomaterials.

[9]  B. Bocca,et al.  Genotoxicity, biodistribution and toxic effects of silver nanoparticles after in vivo acute oral administration , 2020 .

[10]  F. Maranghi,et al.  Hazard identification of pyrogenic synthetic amorphous silica (NM-203) after sub-chronic oral exposure in rat: A multitarget approach. , 2020, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[11]  R. Bleys,et al.  Silicon dioxide and titanium dioxide particles found in human tissues , 2020, Nanotoxicology.

[12]  P. Moos,et al.  Genotoxicity of amorphous silica nanoparticles: Status and prospects. , 2019, Nanomedicine : nanotechnology, biology, and medicine.

[13]  Paul Tobback,et al.  Re‐evaluation of silicon dioxide (E 551) as a food additive , 2018, EFSA journal. European Food Safety Authority.

[14]  D. K. Kuznetsov,et al.  A paradoxical response of the rat organism to long-term inhalation of silica-containing submicron (predominantly nanoscale) particles of a collected industrial aerosol at realistic exposure levels. , 2017, Toxicology.

[15]  J. Jimenez-Villarreal,et al.  Relationship between lymphocyte DNA fragmentation and dose of iron oxide (Fe2O3) and silicon oxide (SiO2) nanoparticles. , 2017, Genetics and molecular research : GMR.

[16]  Jae Ho Song,et al.  Biokinetics of food additive silica nanoparticles and their interactions with food components. , 2017, Colloids and surfaces. B, Biointerfaces.

[17]  T. Downs,et al.  Weak silica nanomaterial-induced genotoxicity can be explained by indirect DNA damage as shown by the OGG1-modified comet assay and genomic analysis , 2017, Mutagenesis.

[18]  Soo-Jin Choi,et al.  Bioavailability of Silica, Titanium Dioxide, and Zinc Oxide Nanoparticles in Rats. , 2016, Journal of nanoscience and nanotechnology.

[19]  Abderrahim Nemmar,et al.  Oxidative stress, inflammation, and DNA damage in multiple organs of mice acutely exposed to amorphous silica nanoparticles , 2016, International journal of nanomedicine.

[20]  M. Wiemann,et al.  In vitro and in vivo genotoxicity investigations of differently sized amorphous SiO2 nanomaterials. , 2015, Mutation research. Genetic toxicology and environmental mutagenesis.

[21]  A. Raggi,et al.  Quantitative characterization of silica nanoparticles by asymmetric flow field flow fractionation coupled with online multiangle light scattering and ICP-MS/MS detection , 2015 .

[22]  W. D. de Jong,et al.  Novel insights into the risk assessment of the nanomaterial synthetic amorphous silica, additive E551, in food , 2015, Nanotoxicology.

[23]  Valérie Fessard,et al.  Toxicity, genotoxicity and proinflammatory effects of amorphous nanosilica in the human intestinal Caco-2 cell line. , 2015, Toxicology in vitro : an international journal published in association with BIBRA.

[24]  V. Fessard,et al.  Genotoxicity of synthetic amorphous silica nanoparticles in rats following short‐term exposure, part 2: Intratracheal instillation and intravenous injection , 2015, Environmental and molecular mutagenesis.

[25]  Henriqueta Louro,et al.  Genotoxicity of synthetic amorphous silica nanoparticles in rats following short‐term exposure. Part 1: Oral route , 2015, Environmental and molecular mutagenesis.

[26]  Jong Yun Lee,et al.  Undetactable levels of genotoxicity of SiO2 nanoparticles in in vitro and in vivo tests , 2014, International journal of nanomedicine.

[27]  Y. Yoshioka,et al.  Intestinal absorption and biological effects of orally administered amorphous silica particles , 2014, Nanoscale Research Letters.

[28]  Stefan Pfuhler,et al.  Silica nanoparticles administered at the maximum tolerated dose induce genotoxic effects through an inflammatory reaction while gold nanoparticles do not. , 2012, Mutation research.

[29]  Douglas Gilliland,et al.  Amorphous silica nanoparticles do not induce cytotoxicity, cell transformation or genotoxicity in Balb/3T3 mouse fibroblasts. , 2012, Mutation research.

[30]  Claudia Fruijtier-Pölloth The toxicological mode of action and the safety of synthetic amorphous silica-a nanostructured material. , 2012, Toxicology.

[31]  H. Bouwmeester,et al.  Presence and risks of nanosilica in food products , 2011, Nanotoxicology.

[32]  Wim H de Jong,et al.  Genotoxicity evaluation of amorphous silica nanoparticles of different sizes using the micronucleus and the plasmid lacZ gene mutation assay , 2011, Nanotoxicology.

[33]  Riccardo Crebelli,et al.  Toxic and genotoxic effects of oral administration of furan in mouse liver. , 2010, Mutagenesis.

[34]  R R Tice,et al.  Recommendations for conducting the in vivo alkaline Comet assay. 4th International Comet Assay Workshop. , 2003, Mutagenesis.

[35]  R. Tice,et al.  Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing , 2000, Environmental and molecular mutagenesis.