Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome
暂无分享,去创建一个
J. Diffley | Alessandro Costa | J. Locke | A. Nans | P. Eickhoff | M. Douglas | P. Goswami | F. Abid Ali | A. Purkiss | A. Janska | A. Early | A. Cheung | Agnieszka Janska
[1] S. Boulton,et al. POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication , 2018, Molecular cell.
[2] R. Xu,et al. A mechanism for preventing asymmetric histone segregation onto replicating DNA strands , 2018, Science.
[3] Alessandro Costa,et al. The mechanism of eukaryotic CMG helicase activation , 2018, Nature.
[4] J. Diffley,et al. Cryo-EM structure of a licensed DNA replication origin , 2017, Nature Communications.
[5] R. Martienssen,et al. Coordinated regulation of heterochromatin inheritance by Dpb3–Dpb4 complex , 2017, Proceedings of the National Academy of Sciences.
[6] B. Stillman,et al. Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model , 2017, Proceedings of the National Academy of Sciences.
[7] J. Diffley,et al. Cdt1 stabilizes an open MCM ring for helicase loading , 2017, Nature Communications.
[8] J. Diffley,et al. CMG–Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome , 2017, Proceedings of the National Academy of Sciences.
[9] D. Agard,et al. MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy , 2017, Nature Methods.
[10] M. Botchan,et al. Mechanisms for initiating cellular DNA replication , 2017, Science.
[11] Hao Wu,et al. Open-ringed structure of the Cdt1–Mcm2–7 complex as a precursor of the MCM double hexamer , 2017, Nature Structural &Molecular Biology.
[12] S. Bell,et al. Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase , 2017, Genes & development.
[13] M. O’Donnell,et al. Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation , 2017, Proceedings of the National Academy of Sciences.
[14] J. Diffley,et al. How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication , 2017, Molecular cell.
[15] Wolfgang Baumeister,et al. Using the Volta phase plate with defocus for cryo-EM single particle analysis , 2016, bioRxiv.
[16] L. Pellegrini,et al. New Insights into the Mechanism of DNA Duplication by the Eukaryotic Replisome. , 2016, Trends in biochemical sciences.
[17] Rafael Fernandez-Leiro,et al. A pipeline approach to single-particle processing in RELION , 2016, bioRxiv.
[18] Sjors H. W. Scheres,et al. Unravelling biological macromolecules with cryo-electron microscopy , 2016, Nature.
[19] S. Bell,et al. Chromosome Duplication in Saccharomyces cerevisiae , 2016, Genetics.
[20] Alessandro Costa,et al. The MCM Helicase Motor of the Eukaryotic Replisome. , 2016, Journal of molecular biology.
[21] J. Diffley,et al. MCM: one ring to rule them all. , 2016, Current opinion in structural biology.
[22] J. Diffley,et al. Phosphopeptide binding by Sld3 links Dbf4‐dependent kinase to MCM replicative helicase activation , 2016, The EMBO journal.
[23] Jin Chuan Zhou,et al. Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate , 2016, Nature Communications.
[24] M. O’Donnell,et al. Structure of the eukaryotic replicative CMG helicase and pumpjack motion , 2016, Nature Structural &Molecular Biology.
[25] B. Chait,et al. The architecture of a eukaryotic replisome , 2015, Nature Structural &Molecular Biology.
[26] Y. Shirakihara,et al. The quaternary structure of the eukaryotic DNA replication proteins Sld7 and Sld3. , 2015, Acta crystallographica. Section D, Biological crystallography.
[27] Kai Zhang,et al. Gctf: Real-time CTF determination and correction , 2015, bioRxiv.
[28] N. Grigorieff,et al. CTFFIND4: Fast and accurate defocus estimation from electron micrographs , 2015, bioRxiv.
[29] T. Tahirov,et al. Crystal Structure of the Human Pol α B Subunit in Complex with the C-terminal Domain of the Catalytic Subunit* , 2015, The Journal of Biological Chemistry.
[30] J. Diffley,et al. Regulated Eukaryotic DNA Replication Origin Firing with Purified Proteins , 2015, Nature.
[31] M. Botchan,et al. Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement , 2015, Proceedings of the National Academy of Sciences.
[32] M. O’Donnell,et al. CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication , 2014, Proceedings of the National Academy of Sciences.
[33] J. Diffley,et al. Origin Licensing Requires ATP Binding and Hydrolysis by the MCM Replicative Helicase , 2014, Molecular cell.
[34] S. Bell,et al. Multiple functions for Mcm2-7 ATPase motifs during replication initiation. , 2014, Molecular cell.
[35] E. Johansson,et al. Structural basis for processive DNA synthesis by yeast DNA polymerase ɛ , 2013, Nature Structural &Molecular Biology.
[36] J. Berger,et al. Mechanisms for initiating cellular DNA replication. , 2013, Annual review of biochemistry.
[37] K. Labib,et al. Dpb2 Integrates the Leading-Strand DNA Polymerase into the Eukaryotic Replisome , 2013, Current Biology.
[38] Rubben Torella,et al. Mechanism for priming DNA synthesis by yeast DNA Polymerase α , 2013, eLife.
[39] E. Johansson,et al. The C-terminus of Dpb2 is required for interaction with Pol2 and for cell viability , 2012, Nucleic acids research.
[40] Tatsuro S. Takahashi,et al. DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast , 2012, Molecular biology of the cell.
[41] M. Botchan,et al. ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryote , 2012, Proceedings of the National Academy of Sciences.
[42] Chris P. Ponting,et al. Cdc45: the missing RecJ ortholog in eukaryotes? , 2011, Bioinform..
[43] J. Berger,et al. The nuts and bolts of ring-translocase structure and mechanism. , 2011, Current opinion in structural biology.
[44] M. Botchan,et al. The structural basis for MCM2–7 helicase activation by GINS and Cdc45 , 2011, Nature Structural &Molecular Biology.
[45] Alan Poulter,et al. One ring to rule them all , 2010 .
[46] K. Labib. How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells? , 2010, Genes & development.
[47] S. MacNeill,et al. The eukaryotic replicative DNA polymerases take shape. , 2010, Trends in biochemical sciences.
[48] H. Araki,et al. CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol (epsilon}, and GINS in budding yeast. , 2010, Genes & development.
[49] M. Botchan,et al. Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins. , 2010, Molecular cell.
[50] Vincent B. Chen,et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution , 2010, Acta crystallographica. Section D, Biological crystallography.
[51] Jingchuan Sun,et al. A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication , 2009, Proceedings of the National Academy of Sciences.
[52] J. Diffley,et al. Eukaryotic DNA replication control: lock and load, then fire. , 2009, Current opinion in cell biology.
[53] J. Diffley,et al. Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing , 2009, Cell.
[54] Eugene V Koonin,et al. Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol ε and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors , 2009, Biology Direct.
[55] Sabine Pruggnaller,et al. A visualization and segmentation toolbox for electron microscopy. , 2008, Journal of structural biology.
[56] H. Pospiech,et al. The solution structure of the amino-terminal domain of human DNA polymerase ε subunit B is homologous to C-domains of AAA+ proteins , 2008, Nucleic acids research.
[57] S. Bell,et al. Subunit Organization of Mcm2-7 and the Unequal Role of Active Sites in ATP Hydrolysis and Viability , 2008, Molecular and Cellular Biology.
[58] Hiroyuki Araki,et al. CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast , 2007, Nature.
[59] J. Diffley,et al. Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast , 2007, Nature.
[60] L. Joshua-Tor,et al. Mechanism of DNA translocation in a replicative hexameric helicase , 2006, Nature.
[61] S. Bell,et al. Organization of the archaeal MCM complex on DNA and implications for the helicase mechanism , 2005, Nature Structural &Molecular Biology.
[62] Johannes Söding,et al. The HHpred interactive server for protein homology detection and structure prediction , 2005, Nucleic Acids Res..
[63] Conrad C. Huang,et al. UCSF Chimera—A visualization system for exploratory research and analysis , 2004, J. Comput. Chem..
[64] A. Sugino,et al. [DNA polymerase epsilon]. , 2002, Seikagaku. The Journal of Japanese Biochemical Society.
[65] Wenyi Feng,et al. Schizosaccharomyces pombe Cells Lacking the Amino-Terminal Catalytic Domains of DNA Polymerase Epsilon Are Viable but Require the DNA Damage Checkpoint Control , 2001, Molecular and Cellular Biology.
[66] D. Levy,et al. Analysis of the Essential Functions of the C-terminal Protein/Protein Interaction Domain of Saccharomyces cerevisiae pol ε and Its Unexpected Ability to Support Growth in the Absence of the DNA Polymerase Domain* , 1999, The Journal of Biological Chemistry.
[67] M. O’Donnell,et al. Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation , 2016 .
[68] E. Johansson,et al. DNA polymerase ε. , 2012, Sub-cellular biochemistry.
[69] Friedrich Förster,et al. Visual proteomics. , 2010, Methods in enzymology.
[70] Friedrich Förster,et al. Structure determination in situ by averaging of tomograms. , 2007, Methods in cell biology.
[71] Wen Jiang,et al. EMAN2: an extensible image processing suite for electron microscopy. , 2007, Journal of structural biology.
[72] Karen N. Allen,et al. research papers Acta Crystallographica Section D Biological , 2003 .