Improved 3D phase contrast MRI with off‐resonance corrected dual echo VIPR

Phase contrast (PC) magnetic resonance imaging with a three‐dimensional, radially undersampled acquisition allows for the acquisition of high resolution angiograms and velocimetry in dramatically reduced scan times. However, such an acquisition is sensitive to blurring and artifacts from off‐resonance and trajectory errors. A dual‐echo trajectory is proposed with a novel trajectory calibration from prescan data coupled with a multi‐frequency reconstruction to correct for these errors. Comparisons of phantom data and in vivo results from volunteer, and patients with arteriovenous malformations patients are presented with and without these corrections and show significant improvement of image quality when both corrections are applied. The results demonstrate significantly improved visualization of vessels, allowing for highly accelerated PC acquisitions without sacrifice in image quality. Magn Reson Med 60:1329–1336, 2008. © 2008 Wiley‐Liss, Inc.

[1]  Michael Markl,et al.  Multicoil Dixon chemical species separation with an iterative least‐squares estimation method , 2004, Magnetic resonance in medicine.

[2]  J. Pauly,et al.  A homogeneity correction method for magnetic resonance imaging with time-varying gradients. , 1991, IEEE transactions on medical imaging.

[3]  A Macovski,et al.  Multifrequency interpolation for fast off‐resonance correction , 1997, Magnetic resonance in medicine.

[4]  N J Pelc,et al.  Minimizing TE in moment‐nulled or flow‐encoded two‐and three‐dimensional gradient‐echo imaging , 1992, Journal of magnetic resonance imaging : JMRI.

[5]  Michael Markl,et al.  Time‐resolved three‐dimensional phase‐contrast MRI , 2003, Journal of magnetic resonance imaging : JMRI.

[6]  Hugo R. Shi,et al.  Toeplitz-based iterative image reconstruction for MRI with correction for magnetic field inhomogeneity , 2005, IEEE Transactions on Signal Processing.

[7]  S. Wolff,et al.  Baseline correction of phase contrast images improves quantification of blood flow in the great vessels. , 2007, Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance.

[8]  G. Glover,et al.  Encoding strategies for three‐direction phase‐contrast MR imaging of flow , 1991, Journal of magnetic resonance imaging : JMRI.

[9]  N J Pelc,et al.  Magnetic resonance velocity imaging using a fast spiral phase contrast sequence , 1994, Magnetic resonance in medicine.

[10]  G. Schuierer,et al.  Intracranial vascular stenosis and occlusion: comparison of 3D time-of-flight and 3D phase-contrast MR angiography , 1998, Neuroradiology.

[11]  Ian Marshall,et al.  MRI measurement of time‐resolved wall shear stress vectors in a carotid bifurcation model, and comparison with CFD predictions , 2003, Journal of magnetic resonance imaging : JMRI.

[12]  W. Manning,et al.  Simultaneous acquisition of spatial harmonics (SMASH): Fast imaging with radiofrequency coil arrays , 1997, Magnetic resonance in medicine.

[13]  Douglas C. Noll,et al.  Deblurring for non‐2D fourier transform magnetic resonance imaging , 1992, Magnetic resonance in medicine.

[14]  Walter F Block,et al.  Fat/water separation in single acquisition steady‐state free precession using multiple echo radial trajectories , 2005, Magnetic resonance in medicine.

[15]  Walter F Block,et al.  Rapid fat‐suppressed isotropic steady‐state free precession imaging using true 3D multiple‐half‐echo projection reconstruction , 2005, Magnetic resonance in medicine.

[16]  H. Thomsen,et al.  Is there a causal relation between the administration of gadolinium based contrast media and the development of nephrogenic systemic fibrosis (NSF)? , 2006, Clinical radiology.

[17]  Walter F Block,et al.  Time‐resolved contrast‐enhanced imaging with isotropic resolution and broad coverage using an undersampled 3D projection trajectory , 2002, Magnetic resonance in medicine.

[18]  J A Frank,et al.  Simple correction method for k-space trajectory deviations in MRI. , 1998, Journal of magnetic resonance.

[19]  James G Pipe,et al.  Generation and visualization of four-dimensional MR angiography data using an undersampled 3-D projection trajectory , 2006, IEEE Transactions on Medical Imaging.

[20]  Dwight G. Nishimura,et al.  Rapid gridding reconstruction with a minimal oversampling ratio , 2005, IEEE Transactions on Medical Imaging.

[21]  P. Boesiger,et al.  SENSE: Sensitivity encoding for fast MRI , 1999, Magnetic resonance in medicine.

[22]  D. Laidlaw,et al.  Three‐dimensional, time‐resolved (4D) relative pressure mapping using magnetic resonance imaging , 2000, Journal of magnetic resonance imaging : JMRI.

[23]  F. Korosec,et al.  PC VIPR: a high-speed 3D phase-contrast method for flow quantification and high-resolution angiography. , 2005, AJNR. American journal of neuroradiology.

[24]  R L Ehman,et al.  Intracranial aneurysms and vascular malformations: comparison of time-of-flight and phase-contrast MR angiography. , 1991, Radiology.

[25]  M. Bernstein,et al.  Comparison of phase‐difference and complex‐difference processing in phase‐contrast MR angiography , 1991, Journal of magnetic resonance imaging : JMRI.

[26]  Michael Markl,et al.  Time-resolved three-dimensional magnetic resonance velocity mapping of aortic flow in healthy volunteers and patients after valve-sparing aortic root replacement. , 2005, The Journal of thoracic and cardiovascular surgery.