Physical activity as a determinant of fasting and 2‐h post‐challenge glucose: a prospective cohort analysis of the NAVIGATOR trial

To investigate whether previous physical activity levels are associated with blood glucose levels in individuals with impaired glucose tolerance in the context of an international pharmaceutical trial.

[1]  Zygimantas Cepaitis,et al.  Physical activity in the prevention of type 2 diabetes: the Finnish diabetes prevention study. , 2005, Diabetes.

[2]  Daniel Umpierre,et al.  Physical activity advice only or structured exercise training and association with HbA1c levels in type 2 diabetes: a systematic review and meta-analysis. , 2011, JAMA.

[3]  R. Califf,et al.  Prevention of diabetes and cardiovascular disease in patients with impaired glucose tolerance: rationale and design of the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial. , 2008, American heart journal.

[4]  R. Califf,et al.  A novel risk classification paradigm for patients with impaired glucose tolerance and high cardiovascular risk. , 2013, The American journal of cardiology.

[5]  R. Califf,et al.  Predictors of cardiovascular events in a contemporary population with impaired glucose tolerance: an observational analysis of the Nateglinide and Valsartan in impaired glucose tolerance outcomes research (NAVIGATOR) trial , 2012, BMJ Open.

[6]  K. Khunti,et al.  Effectiveness of a Pragmatic Education Program Designed to Promote Walking Activity in Individuals With Impaired Glucose Tolerance , 2009, Diabetes Care.

[7]  W. Kraus,et al.  Association between change in daily ambulatory activity and cardiovascular events in people with impaired glucose tolerance (NAVIGATOR trial): a cohort analysis , 2014, The Lancet.

[8]  J. Hawley.  Exercise as a therapeutic intervention for the prevention and treatment of insulin resistance , 2004, Diabetes/metabolism research and reviews.

[9]  JoAnn E Manson,et al.  Epidemiological evidence for the role of physical activity in reducing risk of type 2 diabetes and cardiovascular disease. , 2005, Journal of applied physiology.

[10]  M. Laakso,et al.  Effect of valsartan on the incidence of diabetes and cardiovascular events. , 2010, The New England journal of medicine.

[11]  L. Goodyear,et al.  Signaling mechanisms in skeletal muscle: Acute responses and chronic adaptations to exercise , 2008, IUBMB life.

[12]  P. Raskin,et al.  Report of the expert committee on the diagnosis and classification of diabetes mellitus. , 1999, Diabetes care.

[13]  Nicola J Cooper,et al.  Different strategies for screening and prevention of type 2 diabetes in adults: cost effectiveness analysis , 2008, BMJ : British Medical Journal.

[14]  Glen P. Kenny,et al.  Effects of Exercise on Glycemic Control and Body Mass in Type 2 Diabetes Mellitus: A Meta-analysis of Controlled Clinical Trials , 2001 .

[15]  B E Ainsworth,et al.  How many days of pedometer monitoring predict weekly physical activity in adults? , 2005, Preventive medicine.

[16]  R. Shephard.  Limits to the measurement of habitual physical activity by questionnaires , 2003, British journal of sports medicine.

[17]  M. Laakso,et al.  Effect of nateglinide on the incidence of diabetes and cardiovascular events. , 2010, The New England journal of medicine.

[18]  F. Hu,et al.  Physical Activity of Moderate Intensity and Risk of Type 2 Diabetes , 2007, Diabetes Care.

[19]  R. Sigal,et al.  Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: a meta‐analysis of controlled clinical trials , 2002, JAMA.