A literature review of autograft and allograft anterior cruciate ligament reconstruction

Knee anterior cruciate ligament reconstructive surgery has significantly evolved and now includes the option of using an allograft. This has resulted in numerous studies evaluating the advantages and disadvantages of allografts. The purpose of this literature review is to evaluate this research and present important findings to allow the selection of the most appropriate graft source when considering allograft versus autograft reconstruction.

[1]  J. Gillquist,et al.  Arthroscopic reconstruction of the anterior cruciate ligament. , 1988, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[2]  Cyril B. Frank,et al.  Current Concepts Review - The Science of Reconstruction of the Anterior Cruciate Ligament* , 1997 .

[3]  D. Lintner,et al.  Patellar tendon defect during the first year after anterior cruciate ligament reconstruction: appearance on serial magnetic resonance imaging. , 1998, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[4]  T. Carter,et al.  Isokinetic evaluation of anterior cruciate ligament reconstruction: hamstring versus patellar tendon. , 1999, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[5]  J. Tibone,et al.  Patellar tendon length change after anterior cruciate ligament reconstruction using the midthird patellar tendon , 1993, The American journal of sports medicine.

[6]  K. Shino,et al.  Maturation of allograft tendons transplanted into the knee. An arthroscopic and histological study. , 1988, The Journal of bone and joint surgery. British volume.

[7]  F. Noyes,et al.  The effects of 4 Mrad of gamma irradiation on the initial mechanical properties of bone-patellar tendon-bone grafts. , 1994, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[8]  J. McCarroll,et al.  Fracture of the patella during a golf swing following reconstruction of the anterior cruciate ligament , 1983, The American journal of sports medicine.

[9]  R. Marcus,et al.  Comparison of anterior cruciate ligament reconstructions using patellar tendon autograft or allograft. , 1996, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[10]  G. Poehling,et al.  Arthroscopic reconstruction of the anterior cruciate ligament using allograft tendon. , 1988, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[11]  B. Cohn,et al.  The effects of in situ freezing on the anterior cruciate ligament. An experimental study in goats. , 1991, The Journal of bone and joint surgery. American volume.

[12]  H. Tullos,et al.  Reconstitution of the Patellar Tendon Donor Site After Graft Harvest , 1995, Clinical orthopaedics and related research.

[13]  L. Pinczewski,et al.  Endoscopic reconstruction for isolated anterior cruciate ligament rupture , 1998 .

[14]  F. Noyes,et al.  Bone-patellar ligament-bone and fascia lata allografts for reconstruction of the anterior cruciate ligament. , 1990, The Journal of bone and joint surgery. American volume.

[15]  J W Katz,et al.  The diagnostic accuracy of ruptures of the anterior cruciate ligament comparing the Lachman test, the anterior drawer sign, and the pivot shift test in acute and chronic knee injuries , 1986, The American journal of sports medicine.

[16]  Spencer K Y Chang,et al.  Anterior cruciate ligament reconstruction: allograft versus autograft. , 2003, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[17]  Suh Jeung‐Tak,et al.  Reconstruction of Anterior Cruciate Ligament with Human Allograft , 2002 .

[18]  D. B. O’Neill,et al.  Arthroscopically Assisted Reconstruction of the Anterior Cruciate Ligament: A Follow-up Report , 2001, The Journal of bone and joint surgery. American volume.

[19]  D. W. Jackson,et al.  Biologic Incorporation of Allograft Anterior Cruciate Ligament Replacements , 1996, Clinical orthopaedics and related research.

[20]  R. Warren,et al.  Replacement of the anterior cruciate ligament using a patellar tendon allograft. An experimental study. , 1986, The Journal of bone and joint surgery. American volume.

[21]  K. Shino,et al.  Reconstruction of the anterior cruciate ligament by allogeneic tendon graft. An operation for chronic ligamentous insufficiency. , 1986, The Journal of bone and joint surgery. British volume.

[22]  P. Indelicato,et al.  The results of fresh-frozen patellar tendon allografts for chronic anterior cruciate ligament deficiency of the knee , 1992, The American journal of sports medicine.

[23]  R. Buzzi,et al.  Patellofemoral problems after intraarticular anterior cruciate ligament reconstruction. , 1993, Clinical orthopaedics and related research.

[24]  C. Yates,et al.  Magnetic resonance imaging evaluation of the patellar tendon after use of its central one-third for anterior cruciate ligament reconstruction , 1992, The American journal of sports medicine.

[25]  J. Karlsson,et al.  The localization of the infrapatellar nerves in the anterior knee region with special emphasis on central third patellar tendon harvest: a dissection study on cadaver and amputated specimens. , 1999, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[26]  D. W. Jackson,et al.  Intraarticular reaction associated with the use of freeze-dried, ethylene oxide-sterilized bone-patella tendon-bone allografts in the reconstruction of the anterior cruciate ligament , 1990, The American journal of sports medicine.

[27]  W. Hartman,et al.  Comparison of perioperative morbidity of anterior cruciate ligament autografts versus allografts. , 1993, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[28]  T. Malinin,et al.  A study of retrieved allografts used to replace anterior cruciate ligaments. , 2002, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[29]  P. Than,et al.  Comparative study of autograft or allograft in primary anterior cruciate ligament reconstruction , 2004, International Orthopaedics.

[30]  C. Vangsness,et al.  Gamma Irradiation: Effects on Biomechanical Properties of Human Bone-Patellar Tendon-Bone Allografts , 1995, The American journal of sports medicine.

[31]  L. Engebretsen,et al.  A prospective, randomized study of three surgical techniques for treatment of acute ruptures of the anterior cruciate ligament , 1990, The American journal of sports medicine.

[32]  J. Uribe,et al.  Intra-articular anterior cruciate ligament reconstruction using patellar tendon allograft in the skeletally immature patient. , 2002, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[33]  M. Järvinen,et al.  Ultrasonographic and Power Doppler Evaluation of the Patellar Tendon Ten Years after Harvesting Its Central Third for Reconstruction of the Anterior Cruciate Ligament , 2004, The American journal of sports medicine.

[34]  D. Drez,et al.  Anterior cruciate ligament reconstruction using freeze-dried, ethylene oxide-sterilized, bone-patellar tendon-bone allografts , 1991, The American journal of sports medicine.

[35]  M. Naughton,et al.  Analysis of outcomes of anterior cruciate ligament repair with 5-year follow-up: allograft versus autograft. , 2003, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[36]  J. Karlsson,et al.  Patellar tendon or semitendinosus tendon autografts for anterior cruciate ligament reconstruction: a prospective, randomized study with a 7-Year follow-up. , 2003, The American journal of sports medicine.

[37]  M. Meyers,et al.  Allograft Failure in Cruciate Ligament Reconstruction , 1995, The American journal of sports medicine.

[38]  M. Asselmeier,et al.  A review of allograft processing and sterilization techniques and their role in transmission of the human immunodeficiency virus , 1993, The American journal of sports medicine.

[39]  D. B. O’Neill,et al.  Arthroscopically Assisted Reconstruction of the Anterior Cruciate Ligament. A Prospective Randomized Analysis of Three Techniques* , 1996, The Journal of bone and joint surgery. American volume.

[40]  C. A. Rockwood,et al.  THE AMERICAN Academy of Orthopaedic Surgeons. , 1988, The Journal of bone and joint surgery. American volume.

[41]  B. Reider,et al.  An in vitro analysis of patellofemoral contact areas and pressures following procurement of the central one-third patellar tendon , 1993, The American journal of sports medicine.

[42]  A. Schepsis,et al.  Allograft use in ACL reconstruction , 1999 .

[43]  S. Howell,et al.  Scientific justification and technique for anterior cruciate ligament reconstruction using autogenous and allogeneic soft-tissue grafts. , 2003, The Orthopedic clinics of North America.

[44]  K. Sell,et al.  Studies on the antigenicity of bone. I. Freeze-dried and deep-frozen bone allografts in rabbits. , 1976, The Journal of bone and joint surgery. American volume.

[45]  T. Wickiewicz,et al.  Arthroscopically assisted reconstruction of the anterior cruciate ligament with use of autogenous patellar-ligament grafts. Results after twenty-four to forty-two months. , 1993, The Journal of bone and joint surgery. American volume.

[46]  Rosenberg Td,et al.  Extensor mechanism function after patellar tendon graft harvest for anterior cruciate ligament reconstruction. , 1992 .

[47]  F. Barber.  Should allografts be used for routine anterior cruciate ligament reconstructions? , 2003, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[48]  C B Frank,et al.  The science of reconstruction of the anterior cruciate ligament. , 1997, The Journal of bone and joint surgery. American volume.

[49]  T. Nguyen,et al.  Graft selection in reconstruction of the anterior cruciate ligament. , 2001, The Journal of bone and joint surgery. British volume.

[50]  J. Karlsson,et al.  Comparison of Traditional and Subcutaneous Patellar Tendon Harvest , 2000, The American journal of sports medicine.

[51]  B. Bach,et al.  Arthroscopic Anterior Cruciate Ligament Reconstruction: A Metaanalysis Comparing Patellar Tendon and Hamstring Tendon Autografts , 2003, The American journal of sports medicine.

[52]  G. Finerman,et al.  MRI and morphology of the insertion of the patellar tendon after graft harvesting. , 1996, The Journal of bone and joint surgery. British volume.

[53]  K. Schulte,et al.  Anterior Cruciate Ligament Surgery 1996: State of the Art? , 1996, Clinical orthopaedics and related research.

[54]  J. Karlsson,et al.  Does the Patellar Tendon Normalize after Harvesting Its Central Third? , 2004, The American journal of sports medicine.

[55]  E. Grood,et al.  A comparison of patellar tendon autograft and allograft used for anterior cruciate ligament reconstruction in the goat model , 1993, The American journal of sports medicine.

[56]  J. Bonamo,et al.  Rupture of the patellar ligament after use of its central third for anterior cruciate reconstruction. A report of two cases. , 1984, The Journal of bone and joint surgery. American volume.

[57]  M. D. Shaieb,et al.  A Prospective Randomized Comparison of Patellar Tendon versus Semitendinosus and Gracilis Tendon Autografts for Anterior Cruciate Ligament Reconstruction * , 2002, The American journal of sports medicine.

[58]  F. Noyes,et al.  Reconstruction of the Anterior Cruciate Ligament with Human Allograft. Comparison of Early and Later Results* , 1996, The Journal of bone and joint surgery. American volume.

[59]  K. Shino,et al.  Replacement of the anterior cruciate ligament by an allogeneic tendon graft. An experimental study in the dog. , 1984, The Journal of bone and joint surgery. British volume.

[60]  J. Richmond,et al.  Patellar versus hamstring tendons in anterior cruciate ligament reconstruction: A meta-analysis. , 2001, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[61]  D. Dandy,et al.  Patellar tendon length after anterior cruciate ligament reconstruction. , 1994, The Journal of bone and joint surgery. British volume.

[62]  Paolo Aglietti,et al.  Patellar Tendon Versus Doubled Semitendinosus and Gracilis Tendons for Anterior Cruciate Ligament Reconstruction , 1994, The American journal of sports medicine.

[63]  D L Butler,et al.  The effects of processing techniques on the mechanical properties of bone-anterior cruciate ligament-bone allografts , 1988, The American journal of sports medicine.

[64]  D. Caborn,et al.  Allograft anterior tibialis tendon with bioabsorbable interference screw fixation in anterior cruciate ligament reconstruction. , 2002, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[65]  J. Hollis,et al.  A biomechanical comparison of three lower extremity tendons for ligamentous reconstruction about the knee. , 2003, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[66]  T. Rosenberg,et al.  Extensor mechanism function after patellar tendon graft harvest for anterior cruciate ligament reconstruction , 1992, The American journal of sports medicine.

[67]  K. Kaneda,et al.  Quantitative evaluation of knee instability and muscle strength after anterior cruciate ligament reconstruction using patellar and quadriceps tendon , 1992, The American journal of sports medicine.

[68]  D. Deehan,et al.  Endoscopic reconstruction of the anterior cruciate ligament with an ipsilateral patellar tendon autograft , 2000 .

[69]  M. Hull,et al.  A biomechanical evaluation of anterior and posterior tibialis tendons as suitable single-loop anterior cruciate ligament grafts. , 2002, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[70]  E. Groves.  OPERATION FOR THE REPAIR OF THE CRUCIAL LIGAMENTS. , 1917 .

[71]  Dale M. Daniel,et al.  Patellofemoral problems after anterior cruciate ligament reconstruction , 1989, The American journal of sports medicine.

[72]  Matthew T Provencher,et al.  Anterior cruciate ligament surgery. , 2008, Orthopedics.

[73]  T. Ochi,et al.  Effect of Gamma Irradiation on Remodeling Process of Tendon Allograft , 2003, Clinical Orthopaedics and Related Research.

[74]  H. Griffiths,et al.  Morphologic changes in the human patellar tendon after bone-tendon-bone anterior cruciate ligament reconstruction. , 1993, Clinical orthopaedics and related research.

[75]  R. K. Peterson,et al.  Allograft versus autograft patellar tendon anterior cruciate ligament reconstruction: A 5-year follow-up. , 2001, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[76]  Deborah M Boni,et al.  Hamstring tendon graft for anterior cruciate ligament reconstruction. , 2002, AORN journal.

[77]  W. Shelton,et al.  Autograft versus allograft anterior cruciate ligament reconstruction. , 1997, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[78]  P. Kannus,et al.  Bone-patellar tendon-bone reconstruction of the anterior cruciate ligament , 1999, International Orthopaedics.

[79]  W. Kaltenbrunner,et al.  Shortening of the patellar tendon after anterior cruciate ligament reconstruction. , 1998, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[80]  R. Johnson,et al.  Five- to ten-year follow-up evaluation after reconstruction of the anterior cruciate ligament. , 1984, Clinical orthopaedics and related research.

[81]  L. Pinczewski,et al.  Arthroscopic reconstruction of the anterior cruciate ligament with patellar-tendon autograft and interference screw fixation. The results at seven years. , 1999, The Journal of bone and joint surgery. British volume.

[82]  M. Dunn,et al.  Development of cell-seeded patellar tendon allografts for anterior cruciate ligament reconstruction. , 2004, Tissue engineering.

[83]  R. Haut,et al.  Biomechanical and histological observations of the dog patellar tendon after removal of its central one-third , 1990, The American journal of sports medicine.

[84]  W A Weijs,et al.  Mechanics of the patellar articulation. Effects of patellar ligament length studied with a mathematical model. , 1987, Acta orthopaedica Scandinavica.

[85]  D. Kuechle,et al.  Allograft anterior cruciate ligament reconstruction in patients over 40 years of age. , 2002, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[86]  M. Brown,et al.  Bone transplantation and human immunodeficiency virus. An estimate of risk of acquired immunodeficiency syndrome (AIDS). , 1989, Clinical orthopaedics and related research.

[87]  O. Sherman,et al.  Anterior cruciate ligament reconstruction: which graft is best? , 2004, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[88]  Freddie H. Fu,et al.  Quadriceps strength and functional capacity after anterior cruciate ligament reconstruction , 1993, The American journal of sports medicine.

[89]  J. Bellemans,et al.  Graft selection in anterior cruciate ligament reconstruction – prospective analysis of patellar tendon autografts compared with allografts , 1997, International Orthopaedics.

[90]  R. Marder,et al.  Prospective evaluation of arthroscopically assisted anterior cruciate ligament reconstruction , 1991, The American journal of sports medicine.

[91]  M. Järvinen,et al.  The Incidence of Patellofemoral Osteoarthritis and Associated Findings 7 Years after Anterior Cruciate Ligament Reconstruction with a Bone-Patellar Tendon-Bone Autograft , 2001, The American journal of sports medicine.

[92]  John C. McCarroll,et al.  Isolated Autogenous Bone-Patellar Tendon-Bone Graft Site Morbidity , 1994, The American journal of sports medicine.

[93]  R. Warren,et al.  Tendon-healing in a bone tunnel. A biomechanical and histological study in the dog. , 1993, The Journal of bone and joint surgery. American volume.

[94]  R. Marti,et al.  Pain after use of the central third of the patellar tendon for cruciate ligament reconstruction. 33 patients followed 2-3 years. , 1994, Acta orthopaedica Scandinavica.

[95]  K. Shino,et al.  Surface blood flow and histology of human anterior cruciate ligament allografts. , 1991, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[96]  R. Buzzi,et al.  Long-term study of anterior cruciate ligament reconstruction for chronic instability using the central one-third patellar tendon and a lateral extraarticular tenodesis , 1992, The American journal of sports medicine.

[97]  A. Seaber,et al.  Anterior cruciate ligament allograft transplantation , 1986, The American journal of sports medicine.

[98]  M. Andrews,et al.  Anterior Cruciate Ligament Allograft Reconstruction in the Skeletally Immature Athlete , 1994, The American journal of sports medicine.

[99]  E. Berg.  Intrinsic healing of a patellar tendon donor site defect after anterior cruciate ligament reconstruction. , 1992, Clinical orthopaedics and related research.

[100]  T. Branch,et al.  Clinical comparison of freeze-dried and fresh frozen patellar tendon allografts for anterior cruciate ligament reconstruction of the knee , 1990, The American journal of sports medicine.

[101]  K. Shino,et al.  Quantitative evaluation after arthroscopic anterior cruciate ligament reconstruction , 1993, The American journal of sports medicine.

[102]  T. Malinin,et al.  Reconstruction of anterior cruciate ligaments with bone-patellar tendon-bone and achilles tendon allografts. , 1994, Clinical orthopaedics and related research.

[103]  T. Wickiewicz,et al.  Reconstruction of the chronically insufficient anterior cruciate ligament with the central third of the patellar ligament. , 1991, The Journal of bone and joint surgery. American volume.

[104]  J. Webb.  Hamstrings and the anterior cruciate ligament deficient knee. , 2001, The Knee.

[105]  J. Karlsson,et al.  Donor-site morbidity and anterior knee problems after anterior cruciate ligament reconstruction using autografts. , 2001, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[106]  J. Andrish,et al.  A biomechanical comparison of different surgical techniques of graft fixation in anterior cruciate ligament reconstruction , 1987, The American journal of sports medicine.

[107]  T. Hortobágyi,et al.  Gait adaptations before and after anterior cruciate ligament reconstruction surgery. , 1997, Medicine and science in sports and exercise.

[108]  J. Smith,et al.  Achilles tendon allograft reconstruction of the anterior cruciate ligament-deficient knee , 1993, The American journal of sports medicine.

[109]  R. Medoff,et al.  Late Patellar Tendon Ruptures after Removal of the Central Third for Anterior Cruciate Ligament Reconstruction , 1996, The American journal of sports medicine.

[110]  G. Poehling,et al.  Cost comparison of anterior cruciate ligament reconstruction: autograft versus allograft. , 2005, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[111]  R. Caspari,et al.  Arthroscopic evaluation of allograft anterior cruciate ligament reconstruction. , 1992, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[112]  L. Hiemstra,et al.  Knee strength deficits after hamstring tendon and patellar tendon anterior cruciate ligament reconstruction. , 2000, Medicine and science in sports and exercise.

[113]  P. Indelicato,et al.  Bone Tunnel Enlargement After Anterior Cruciate Ligament Replacement , 1994, The American journal of sports medicine.

[114]  F. Noyes,et al.  Biomechanical analysis of human ligament grafts used in knee-ligament repairs and reconstructions. , 1984, The Journal of bone and joint surgery. American volume.

[115]  J. Kartus,et al.  Patellar Tendon or Semitendinosus Tendon Autografts for Anterior Cruciate Ligament Reconstruction , 2007, The American journal of sports medicine.

[116]  L. Pinczewski,et al.  Integration of hamstring tendon graft with bone in reconstruction of the anterior cruciate ligament. , 1997, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[117]  J. Irrgang,et al.  Allograft Versus Autograft Anterior Cruciate Ligament Reconstruction: 3- to 5-Year Outcome , 1996, Clinical orthopaedics and related research.