High efficacy of anti DBL4ɛ-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women.

[1]  C. Lim,et al.  Chondroitin Sulfate A-Adhering Plasmodium falciparum-Infected Erythrocytes Express Functionally Important Antibody Epitopes Shared by Multiple Variants , 2010, The Journal of Immunology.

[2]  T. Richie,et al.  The RTS,S malaria vaccine. , 2010, Vaccine.

[3]  A. Salanti,et al.  Can any lessons be learned from the ambiguous glycan binding of PfEMP1 domains? , 2010, Trends in parasitology.

[4]  T. Theander,et al.  Full-Length Recombinant Plasmodium falciparum VAR2CSA Binds Specifically to CSPG and Induces Potent Parasite Adhesion-Blocking Antibodies , 2010, Journal of molecular biology.

[5]  B. Gamain,et al.  Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA , 2010, Proceedings of the National Academy of Sciences.

[6]  T. Theander,et al.  Several domains from VAR2CSA can induce Plasmodium falciparum adhesion-blocking antibodies , 2010, Malaria Journal.

[7]  M. Higgins,et al.  Structural Comparison of Two CSPG-Binding DBL Domains from the VAR2CSA Protein Important in Malaria during Pregnancy , 2009, Journal of molecular biology.

[8]  T. Theander,et al.  Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites. , 2009, International journal for parasitology.

[9]  M. Lemnge,et al.  Epidemiology of malaria in an area prepared for clinical trials in Korogwe, north-eastern Tanzania , 2009, Malaria Journal.

[10]  T. Theander,et al.  Induction of Adhesion-Inhibitory Antibodies against Placental Plasmodium falciparum Parasites by Using Single Domains of VAR2CSA , 2009, Infection and Immunity.

[11]  T. Theander,et al.  VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes. , 2008, The Journal of infectious diseases.

[12]  B. Gamain,et al.  Var2CSA DBL6-epsilon domain expressed in HEK293 induces limited cross-reactive and blocking antibodies to CSA binding parasites , 2008, Malaria Journal.

[13]  Ole Lund,et al.  Structural Insight into Epitopes in the Pregnancy-Associated Malaria Protein VAR2CSA , 2008, PLoS pathogens.

[14]  Joel H. Janes,et al.  Structural polymorphism and diversifying selection on the pregnancy malaria vaccine candidate VAR2CSA. , 2007, Molecular and biochemical parasitology.

[15]  B. Gamain,et al.  Characterization of anti-var2CSA-PfEMP1 cytoadhesion inhibitory mouse monoclonal antibodies. , 2006, Microbes and infection.

[16]  M. Molyneux,et al.  Transcribed var Genes Associated with Placental Malaria in MalawianWomen , 2006, Infection and Immunity.

[17]  Philip Awadalla,et al.  Global genetic diversity and evolution of var genes associated with placental and severe childhood malaria. , 2006, Molecular and biochemical parasitology.

[18]  Stephen J Rogerson,et al.  VAR2CSA is the principal ligand for chondroitin sulfate A in two allogeneic isolates of Plasmodium falciparum. , 2006, Molecular and biochemical parasitology.

[19]  G. Domingo,et al.  Plasmodium falciparum: chondroitin sulfate A is the major receptor for adhesion of parasitized erythrocytes in the placenta. , 2006, Experimental parasitology.

[20]  T. Theander,et al.  Dynamics of anti-VAR2CSA immunoglobulin G response in a cohort of senegalese pregnant women. , 2006, The Journal of infectious diseases.

[21]  M. Molyneux,et al.  Placental Malaria Induces Variant-Specific Antibodies of the Cytophilic Subtypes Immunoglobulin G1 (IgG1) and IgG3 That Correlate with Adhesion Inhibitory Activity , 2005, Infection and Immunity.

[22]  Michael Lanzer,et al.  A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A , 2005, EMBO reports.

[23]  T. Theander,et al.  High level of var2csa transcription by Plasmodium falciparum isolated from the placenta. , 2005, The Journal of infectious diseases.

[24]  B. Gamain,et al.  Identification of multiple chondroitin sulfate A (CSA)-binding domains in the var2CSA gene transcribed in CSA-binding parasites. , 2005, The Journal of infectious diseases.

[25]  P. Deloron,et al.  Variable adhesion abilities and overlapping antigenic properties in placental Plasmodium falciparum isolates. , 2004, The Journal of infectious diseases.

[26]  Thor G. Theander,et al.  Evidence for the Involvement of VAR2CSA in Pregnancy-associated Malaria , 2004, The Journal of experimental medicine.

[27]  E. J. Mann,et al.  Antibodies to variant surface antigens of Plasmodium falciparum-infected erythrocytes and adhesion inhibitory antibodies are associated with placental malaria and have overlapping and distinct targets. , 2004, The Journal of infectious diseases.

[28]  Kevin Marsh,et al.  Variant surface antigen-specific IgG and protection against clinical consequences of pregnancy-associated Plasmodium falciparum malaria , 2004, The Lancet.

[29]  Joseph D. Smith,et al.  Evidence for the importance of genetic structuring to the structural and functional specialization of the Plasmodium falciparum var gene family , 2003, Molecular microbiology.

[30]  M. Fried,et al.  Antibodies That Inhibit Plasmodium falciparum Adhesion to Chondroitin Sulfate A Are Associated with Increased Birth Weight and the Gestational Age of Newborns , 2003, Infection and Immunity.

[31]  G. Fouda,et al.  Changes in the levels of chemokines and cytokines in the placentas of women with Plasmodium falciparum malaria. , 2003, The Journal of infectious diseases.

[32]  S. Lindsay,et al.  Relationship Between Altitude and Intensity of Malaria Transmission in the Usambara Mountains, Tanzania , 2003, Journal of medical entomology.

[33]  Thomas Lavstsen,et al.  Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A‐adhering Plasmodium falciparum involved in pregnancy‐associated malaria , 2003, Molecular microbiology.

[34]  L. Hviid,et al.  Expression of Variant Surface Antigens by Plasmodium falciparum Parasites in the Peripheral Blood of Clinically Immune Pregnant Women Indicates Ongoing Placental Infection , 2003, Infection and Immunity.

[35]  K. Marsh,et al.  Impaired uteroplacental blood flow in pregnancies complicated by falciparum malaria , 2002, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[36]  M. Wahlgren,et al.  Role of Nonimmune IgG Bound to PfEMP1 in Placental Malaria , 2001, Science.

[37]  M. Valiyaveettil,et al.  Structural Requirements for the Adherence ofPlasmodium falciparum-infected Erythrocytes to Chondroitin Sulfate Proteoglycans of Human Placenta* , 2000, The Journal of Biological Chemistry.

[38]  François Nosten,et al.  Maternal antibodies block malaria , 1998, Nature.

[39]  Kevin Marsh,et al.  Parasite antigens on the infected red cell surface are targets for naturally acquired immunity to malaria , 1998, Nature Medicine.

[40]  M. Fried,et al.  Maternal malaria and parasite adhesion , 1998, Journal of Molecular Medicine.

[41]  B. Nahlen,et al.  A simple perfusion technique for isolation of maternal intervillous blood mononuclear cells from human placentae. , 1997, Journal of immunological methods.

[42]  S. Rogerson,et al.  Chondroitin sulphate A as an adherence receptor for Plasmodium falciparum-infected erythrocytes. , 1997, Parasitology today.

[43]  R. Steketee,et al.  The problem of malaria and malaria control in pregnancy in sub-Saharan Africa. , 1996, The American journal of tropical medicine and hygiene.

[44]  Patrick E. Duffy,et al.  Adherence of Plasmodium falciparum to Chondroitin Sulfate A in the Human Placenta , 1996, Science.

[45]  M. Akogbeto,et al.  Malaria transmission in the lagoon area of Cotonou, Benin. , 1992, Parassitologia.

[46]  D. Warhurst,et al.  SEPARATION OF MALARIA-INFECTED ERYTHROCYTES FROM WHOLE BLOOD: USE OF A SELECTIVE HIGH-GRADIENT MAGNETIC SEPARATION TECHNIQUE , 1981, The Lancet.

[47]  W. Trager,et al.  Human malaria parasites in continuous culture. , 1976, Science.

[48]  E WILSON,et al.  Pheumothorax after thyroidectomy. , 1947, Lancet.

[49]  B. Brabin An analysis of malaria in pregnancy in Africa. , 1983, Bulletin of the World Health Organization.

[50]  M. E. Wilson,et al.  Malaria infection of the placenta in The Gambia, West Africa; its incidence and relationship to stillbirth, birthweight and placental weight. , 1983, Transactions of the Royal Society of Tropical Medicine and Hygiene.