Synthesis and hydrolysis by cathepsin B of fluorogenic substrates with the general structure benzoyl-X-ARG-MCA containing non-natural basic amino acids at position X.
暂无分享,去创建一个
G. Caliendo | V. Santagada | E. Perissutti | L. Juliano | M. Juliano | R. L. Melo | L. C. Alves | R. C. Barbosa Pozzo
[1] L. Juliano,et al. Probing the specificity of cysteine proteinases at subsites remote from the active site: analysis of P4, P3, P2' and P3' variations in extended substrates. , 2000, The Biochemical journal.
[2] G. Veeneman,et al. Solution-phase and solid-phase synthesis of novel transition state inhibitors of coagulation enzymes incorporating a piperidinyl moiety. , 1999, Bioorganic & medicinal chemistry letters.
[3] Y. Imai,et al. The crystal structure of human cathepsin L complexed with E‐64 , 1997, FEBS letters.
[4] R. Ménard,et al. Potency and selectivity of the cathepsin L propeptide as an inhibitor of cysteine proteases. , 1996, Biochemistry.
[5] B. Posner,et al. Endosomal proteolysis of internalized proteins , 1996, FEBS letters.
[6] L. Juliano,et al. Synthesis of N alpha-protected aminoacyl 7-amino-4-methyl-coumarin amide by phosphorous oxychloride and preparation of specific fluorogenic substrates for papain. , 1996, Peptide research.
[7] C. P. Huber,et al. Characterization of the S Subsite Specificity of Cathepsin B (*) , 1995, The Journal of Biological Chemistry.
[8] C. P. Huber,et al. Crystal Structures of Recombinant Rat Cathepsin B and a Cathepsin B-Inhibitor Complex , 1995, The Journal of Biological Chemistry.
[9] P. Bonneau,et al. Engineering the S2 subsite specificity of human cathepsin S to a cathepsin L- and cathepsin B-like specificity. , 1994, The Journal of biological chemistry.
[10] J. Palmer,et al. Cysteine proteinase inhibitors decrease articular cartilage and bone destruction in chronic inflammatory arthritis. , 1994, Arthritis and rheumatism.
[11] W. F. Hoffman,et al. A simple and inexpensive synthesis of 4-(aminomethyl)-L-phenylalanine , 1993 .
[12] C. P. Huber,et al. Characterization of cathepsin B specificity by site-directed mutagenesis. Importance of Glu245 in the S2-P2 specificity for arginine and its role in transition state stabilization. , 1993, The Journal of biological chemistry.
[13] R. Ménard,et al. Engineering of papain: selective alteration of substrate specificity by site-directed mutagenesis. , 1991, Biochemistry.
[14] Robert Huber,et al. The refined 2.15 A X‐ray crystal structure of human liver cathepsin B: the structural basis for its specificity. , 1991, The EMBO journal.
[15] J. Bozell,et al. Transition-metal-assisted asymmetric synthesis of amino acid analogs. A new synthesis of optically pure D- and L-pyridylalanines , 1991 .
[16] C. Acosta,et al. SYNTHESIS OF cis AND trans-4-AMINOCYCLOHEXYL-D-ALANINE DERIVATIVES AND DETERMINATION OF THEIR STEREOCHEMISTRY , 1991 .
[17] R. Ménard,et al. A protein engineering study of the role of aspartate 158 in the catalytic mechanism of papain. , 1990, Biochemistry.
[18] L. Juliano,et al. Ionization constants and thermodynamic parameters of histidine and derivatives , 1983 .
[19] L. Juliano,et al. Ionization of methyl derivatives of imidazole, histidine, thyreotropin releasing factor, and related compounds. , 1976, Journal of the American Chemical Society.
[20] L. Juliano,et al. Conformation of angiotensin II in aqueous solution. Titration of several peptide analogs and homologs. , 1974, Biochemistry.
[21] G. N. Wilkinson. Statistical estimations in enzyme kinetics. , 1961, The Biochemical journal.
[22] M. Mcgrath. The lysosomal cysteine proteases. , 1999, Annual review of biophysics and biomolecular structure.
[23] N. Rawlings,et al. Proteinases 1: lysosomal cysteine proteinases. , 1995, Protein profile.
[24] Bonnie F. Sloane,et al. Chapter 12 – Regulation of Lysosomal Endopeptidases in Malignant Neoplasia , 1994 .
[25] R. Ménard,et al. Catalytic mechanism in papain family of cysteine peptidases. , 1994, Methods in enzymology.
[26] A. Barrett. [57] Cystatin, the egg white inhibitor of cysteine proteinases , 1981 .
[27] Alan J. Barrett,et al. [41] Cathepsin B, cathepsin H, and cathepsin L , 1981 .