Crystal structure and interactions of the PAS repeat region of the Drosophila clock protein PERIOD.

[1]  A. Voss,et al.  Interaction of the PAS B Domain with HSP90 Accelerates Hypoxia-Inducible Factor-1α Stabilization , 2004, Cellular Physiology and Biochemistry.

[2]  P. Nawathean,et al.  The doubletime and CKII kinases collaborate to potentiate Drosophila PER transcriptional repressor activity. , 2004, Molecular cell.

[3]  K. Gardner,et al.  Structural basis for PAS domain heterodimerization in the basic helix–loop–helix-PAS transcription factor hypoxia-inducible factor , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[4]  Kevin H. Gardner,et al.  Structural Basis of a Phototropin Light Switch , 2003, Science.

[5]  Dagmar Ringe,et al.  POVScript+: a program for model and data visualization using persistence of vision ray-tracing , 2003 .

[6]  S. Reppert,et al.  SUPPLEMENTAL EXPERIMENTAL PROCEDURES , 2012 .

[7]  P. Hegemann,et al.  Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii. , 2003, Biophysical journal.

[8]  F. Jackson,et al.  A role for CK2 in the Drosophila circadian oscillator , 2003, Nature Neuroscience.

[9]  Kevin P. Keegan,et al.  A role for casein kinase 2α in the Drosophila circadian clock , 2002, Nature.

[10]  Jared Rutter,et al.  Structure and interactions of PAS kinase N-terminal PAS domain: model for intramolecular kinase regulation. , 2002, Structure.

[11]  P. Hardin,et al.  Central and peripheral circadian oscillator mechanisms in flies and mammals. , 2002, Journal of cell science.

[12]  J. Truman,et al.  Sequential Nuclear Accumulation of the Clock Proteins Period and Timeless in the Pacemaker Neurons of Drosophila melanogaster , 2002, The Journal of Neuroscience.

[13]  E. Nishida,et al.  Control of Intracellular Dynamics of Mammalian Period Proteins by Casein Kinase I ε (CKIε) and CKIδ in Cultured Cells , 2002, Molecular and Cellular Biology.

[14]  D. Virshup,et al.  Nuclear Export of Mammalian PERIOD Proteins* , 2001, The Journal of Biological Chemistry.

[15]  C. Kyriacou,et al.  Light-dependent interaction between Drosophila CRY and the clock protein PER mediated by the carboxy terminus of CRY , 2001, Current Biology.

[16]  K. Moffat,et al.  Structure of a flavin-binding plant photoreceptor domain: Insights into light-mediated signal transduction , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[17]  Michael J. McDonald,et al.  Wild-Type Circadian Rhythmicity Is Dependent on Closely Spaced E Boxes in the Drosophila timelessPromoter , 2001, Molecular and Cellular Biology.

[18]  Paolo Sassone-Corsi,et al.  Multilevel regulation of the circadian clock , 2000, Nature Reviews Molecular Cell Biology.

[19]  F. Tamanini,et al.  Dimerization and nuclear entry of mPER proteins in mammalian cells. , 2000, Genes & development.

[20]  Michael W. Young,et al.  A TIMELESS-Independent Function for PERIOD Proteins in the Drosophila Clock , 2000, Neuron.

[21]  I. Zhulin,et al.  PAS Domains: Internal Sensors of Oxygen, Redox Potential, and Light , 1999, Microbiology and Molecular Biology Reviews.

[22]  D E McRee,et al.  XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density. , 1999, Journal of structural biology.

[23]  J. Dunlap Molecular Bases for Circadian Clocks , 1999, Cell.

[24]  M. Gilles-Gonzalez,et al.  Structure of a biological oxygen sensor: a new mechanism for heme-driven signal transduction. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[25]  Steven L. Cohen,et al.  DEPARTMENT OF PHYSIOLOGY: 2016/2017 LT/LE ORGANIZATION CHART , 2016 .

[26]  Joel D Levine,et al.  Molecular Analysis of Mammalian Timeless , 1998, Neuron.

[27]  R J Read,et al.  Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.

[28]  Michael W Young,et al.  The Drosophila Clock Gene double-time Encodes a Protein Closely Related to Human Casein Kinase Iε , 1998, Cell.

[29]  M. W. Young,et al.  double-time Is a Novel Drosophila Clock Gene that Regulates PERIOD Protein Accumulation , 1998, Cell.

[30]  L. A. Sawyer,et al.  Natural variation in a Drosophila clock gene and temperature compensation. , 1997, Science.

[31]  J. Pelletier,et al.  The murine Sim-2 gene product inhibits transcription by active repression and functional interference , 1997, Molecular and cellular biology.

[32]  J. Hogenesch,et al.  Characterization of a Subset of the Basic-Helix-Loop-Helix-PAS Superfamily That Interacts with Components of the Dioxin Signaling Pathway* , 1997, The Journal of Biological Chemistry.

[33]  Michael W Young,et al.  Regulation of Nuclear Entry of the Drosophila Clock Proteins Period and Timeless , 1996, Neuron.

[34]  Zuwei Qian,et al.  A light-entrainment mechanism for the Drosophila circadian clock , 1996, Nature.

[35]  A. Sehgal,et al.  Isolation of timeless by PER Protein Interaction: Defective Interaction Between timeless Protein and Long-Period Mutant PERL , 1995, Science.

[36]  D. Schomburg,et al.  Evaluation of protein 3-D structure prediction: comparison of modelled and X-ray structure of an alkaline serine protease. , 1995, Journal of biotechnology.

[37]  G. Borgstahl,et al.  1.4 A structure of photoactive yellow protein, a cytosolic photoreceptor: unusual fold, active site, and chromophore. , 1995, Biochemistry.

[38]  M. Rosbash,et al.  PER protein interactions and temperature compensation of a circadian clock in Drosophila , 1995, Science.

[39]  M. Rosbash,et al.  Temporally regulated nuclear entry of the Drosophila period protein contributes to the circadian clock , 1995, Neuron.

[40]  J. Thompson,et al.  CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. , 1994, Nucleic acids research.

[41]  E A Merritt,et al.  Raster3D Version 2.0. A program for photorealistic molecular graphics. , 1994, Acta crystallographica. Section D, Biological crystallography.

[42]  O. Hankinson,et al.  Identification of Functional Domains of the Aryl Hydrocarbon Receptor (*) , 1995, The Journal of Biological Chemistry.

[43]  M. Lawrence,et al.  Shape complementarity at protein/protein interfaces. , 1993, Journal of molecular biology.

[44]  Wolfgang Kabsch,et al.  Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants , 1993 .

[45]  M. Rosbash,et al.  PAS is a dimerization domain common to Drosophila Period and several transcription factors , 1993, Nature.

[46]  L. Vosshall,et al.  New short period mutations of the Drosophila clock gene per , 1992, Neuron.

[47]  K. Sharp,et al.  Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons , 1991, Proteins.

[48]  P. Kraulis A program to produce both detailed and schematic plots of protein structures , 1991 .

[49]  J. C. Hall,et al.  Interspecific comparison of the period gene of Drosophila reveals large blocks of non‐conserved coding DNA. , 1988, The EMBO journal.

[50]  R J Konopka,et al.  Clock mutants of Drosophila melanogaster. , 1971, Proceedings of the National Academy of Sciences of the United States of America.

[51]  D. P. King,et al.  Molecular genetics of circadian rhythms in mammals. , 2000, Annual review of neuroscience.

[52]  Arthur J. Rowe,et al.  Analytical ultracentrifugation in biochemistry and polymer science , 1992 .