Time trends and demography of mortality after fractured neck of femur in an English population, 1968–98: database study

Abstract Objectives To investigate time trends in mortality after admission to hospital for fractured neck of femur from 1968 to 1998, and to report on the effects of demographic factors on mortality. Design Analysis of hospital inpatient statistics for fractured neck of femur, incorporating linkage to death certificates. Setting Four counties in southern England. Subjects 32 590 people aged 65 years or over admitted to hospital with fractured neck of femur between 1968 and 1998. Main outcome measures Case fatality rates at 30, 90, and 365 days after admission, and standardised mortality ratios at monthly intervals up to one year after admission. Results Case fatality rates declined between the 1960s and the early 1980s, but there was no appreciable fall thereafter. They increased sharply with increasing age: for example, fatality rates at 30 days in 1984–98 increased from 4% in men aged 64–69 years to 31% in those aged ≥ 90. They were higher in men than women, and in social classes IV and V than in classes I and II. In the first month after fracture, standardised mortality ratios in women were 16 times higher, and those in men 12 times higher, than mortality in the same age group in the general population. Conclusions The high mortality rates, and the fact that they have not fallen over the past 20 years, reinforce the need for measures to prevent osteoporosis and falls and their consequences in elderly people. Whether post-fracture mortality has fallen to an irreducible minimum, or whether further decline is possible, is unclear.

[1]  D. Prudham,et al.  A prospective study of fractured proximal femur: factors predisposing to survival. , 1979, Age and ageing.

[2]  A. Majeed,et al.  Trends in hospital admissions for fractures of the hip and femur in England, 1989-1990 to 1997-1998. , 2001, Journal of public health medicine.

[3]  M. Schroll,et al.  Stroke incidence, case fatality, and mortality in the WHO MONICA project. World Health Organization Monitoring Trends and Determinants in Cardiovascular Disease. , 1995, Stroke.

[4]  J. Raymakers,et al.  Mortality and causes of death after hip fractures in The Netherlands. , 1992, The Netherlands journal of medicine.

[5]  T. Spector,et al.  Trends in admissions for hip fracture in England and Wales, 1968-85. , 1990, BMJ.

[6]  C. Palmer,et al.  Differences in mortality after fracture of hip: the East Anglian audit , 1995, British medical journal.

[7]  H. Tunstall-Pedoe,et al.  Contribution of trends in survival and coronary-event rates to changes in coronary heart disease mortality: 10-year results from 37 WHO MONICA project populations. Monitoring trends and determinants in cardiovascular disease. , 1999, Lancet.

[8]  P. Heuschmann,et al.  Variations in Stroke Incidence and Survival in 3 Areas of Europe , 2000, Stroke.

[9]  M. Vessey,et al.  RISING INCIDENCE OF FRACTURE OF THE PROXIMAL FEMUR , 1985, The Lancet.

[10]  R. Norton,et al.  Mortality after hip fracture: regional variations in New Zealand. , 1999, The New Zealand medical journal.

[11]  Pekka Kannus,et al.  Hip fractures in Finland between 1970 and 1997 and predictions for the future , 1999, The Lancet.

[12]  H. Tunstall-Pedoe,et al.  Contribution of trends in survival and coronar y-event rates to changes in coronary heart disease mortality: 10-year results from 37 WHO MONICA Project populations , 1999, The Lancet.

[13]  J. Falch,et al.  Secular increase and geographical differences in hip fracture incidence in Norway. , 1993, Bone.

[14]  Stephen E Roberts,et al.  Mortality after admission to hospital with fractured neck of femur: database study , 2002, BMJ : British Medical Journal.

[15]  N R Hicks,et al.  Coronary event and case fatality rates in an English population: results of the Oxford myocardial infarction incidence study , 1998, Heart.

[16]  G. Bourke,et al.  Predictors of first hip fracture and mortality post fracture in older women , 2001, Irish journal of medical science.

[17]  M. Goldacre,et al.  Elective total hip replacement: incidence, emergency readmission rate, and postoperative mortality. , 1991, BMJ.

[18]  A. Ahlbom,et al.  Age- and sex-specific incidence of femoral neck and trochanteric fractures. An analysis based on 20,538 fractures in Stockholm County, Sweden, 1972-1981. , 1987, Clinical orthopaedics and related research.

[19]  M Weatherall,et al.  One year follow up of patients with fracture of the proximal femur. , 1994, The New Zealand medical journal.

[20]  M. Goldacre,et al.  Secular trends in proximal femoral fracture, Oxford record linkage study area and England 1968-86. , 1997, Journal of epidemiology and community health.

[21]  D. Gilmore,et al.  Outcome following proximal femoral fracture in the elderly female. , 1991, The Ulster medical journal.

[22]  M. Parker,et al.  Mortality and morbidity after hip fractures. , 1993, BMJ.

[23]  Terje P. Hagen,et al.  What is best and at what cost , 2002 .

[24]  J. Eisman,et al.  Mortality after all major types of osteoporotic fracture in men and women: an observational study , 1999, The Lancet.